Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79868 Plumbagin GSE92742 NEU Human 24h 10uM EID0475
Types Number Response transcription factors
Up-regulation 215 POLR3C; EPAS1; PRDM14; NFKBIB; NFATC4; MED25; ETS1; SPDEF; TFAP2A; CREBL2; IRF6; ZNF74; TUB; E4F1; ZNF415; IRF3; VGLL1; NR5A1; HHEX; SNAI2; HSF1; PROP1; ZNF593; E2F4; NR2F6; ZSCAN2; PEX14; CCNH; PPARA; VDR; CD3D; NR1H2; THAP7; CEBPB; MED14; KDM4C; TP73; TTF2; AIRE; ZNF335; MED15; TAF1C; SNAPC4; RAD21; ATF3; HSF4; E2F2; CDIP1; JUP; NR0B2; KDM5C; YEATS4; VPS72; LZTR1; SRCAP; LIN28A; LYL1; PHF1; DAXX; HOXA3; ZBED2; RB1; TBX21; MNDA; PNRC1; THRB; ZNF225; ZNF350; BARX1; SUPT3H; FOXF2; NFE2; ESR1; FLI1; NKX2-2; COPS5; SOX18; TGFB1; DDIT3; ZNF165; HIRA; FOXM1; TBX5; SOX17; CRYM; HOXA6; ZFP36L2; SUPT5H; MEF2C; HOXD1; EMX1; RING1; NOC2L; ST18; HDAC9; TGFB1I1; CIC; SREBF2; ZNF250; ZNF331; FOXJ2; NR4A3; LHX3; SIX6; LOXL2; FOXH1; STAT1; NR0B1; ZNF155; RFXANK; BRDT; CEBPE; PPP1R13L; ZNF239; NKRF; NKX2-1; CEBPG; TBX1; KAT2B; PRDM10; OVOL2; TLE2; ARID5B; IRF9; ETV6; SNAI1; FOXE1; GATA6; BNC1; TAL1; CALR; ZNF835; SOX13; ZNF544; TRIP6; PBX3; ZNF34; CBX7; WDR77; IFNB1; ZNF141; FOSL1; NR5A2; ZNF444; CREB3; STAT6; TERF1; ELF3; MYC; LITAF; MED21; KLF6; ATF5; MYBL1; ZNF692; PBXIP1; PSMC3; SP100; JAK2; TAF4B; PEG3; ZNF215; HOXB2; EN1; EGR4; ARL2BP; ZNF589; CBFA2T3; NANOG; MXI1; TDP2; CDK2; ACTL6A; SSBP3; BCL11A; GATA1; CEBPD; HOXA5; ILF2; SSBP2; GFI1; NR1I3; IFI16; IRF1; PRDM1; AHR; TCF21; ETV5; TULP3; CTBP2; OSR2; KLF4; STAT4; MECOM; REL; PIR; RBPMS; BCL11B; AR; MAFF; MAFB; HDGF; ZNF557; KLF13; KLF11; TCEA1; BHLHE41; YBX3; KLF1; WT1; JUN; CREB3L1; ZFP36L1; TRIB3; SCAND1
Down-regulation 379 KDM5D; BASP1; SOX4; TOX3; DMTF1; KAT6A; ATF7IP; RBBP4; CRK; MED1; SMARCE1; RBPJ; NFIB; ZNF24; RFX5; FOXO3; CCNA2; CHD7; AATF; KAT7; RHOA; ZNF248; MTF2; TAF4; BCOR; NUP62; TCF4; IL16; PAXBP1; USP22; MED23; BACH2; ZNF3; ZKSCAN1; ZNF14; TERF2; ZMYM2; CHD9; ARID4B; MAX; SOX2; HMG20A; SMARCC1; HNRNPD; PIAS1; ZEB2; KAT6B; E2F5; DDX17; SUZ12; ZBTB18; PHF2; BAZ1B; REST; ZNF189; PATZ1; HSBP1; BRD3; NR2F1; ZKSCAN7; CUX1; CREB1; ZBTB1; BCLAF1; ZNF629; ZNF516; VEZF1; CBX5; PARP1; ZNF468; ZNF292; NCOA1; HEY1; UBP1; SIX1; VGLL4; LIMD1; CTR9; ZMIZ1; ZEB1; PSPC1; SNW1; KDM5B; NFKBIA; NAB1; CHD1; TRRAP; TBP; TAF1D; ZNF532; UBTF; NR2F2; BAZ1A; SFPQ; HLTF; PCGF2; ADNP; MSX1; MGA; CARHSP1; RLF; SETD2; EN2; BIRC2; TCF12; POU2F1; BRPF1; KMT2A; ID2; MLX; ZNF107; ETV1; SP140; ZNF443; MTF1; HDAC6; REPIN1; TRIM32; TTF1; ZNF84; RYBP; PBRM1; ZNF273; TRIM33; KDM5A; ARID1A; ZNF200; RFX7; ZNF146; TCERG1; E2F6; RNF4; MYT1L; SMAD4; BRD8; RARA; ZNF510; SETD3; PSMC3IP; ELF2; HOXB7; HSF2; ECD; ZNF267; RAN; SMARCA5; NEDD8; TP53; PIAS2; IRX5; TAF7; FOXJ3; EYA1; TRAK1; TLE4; CAMTA1; NONO; CREBZF; WWC1; TSC22D3; YWHAB; GABPB1; NFIL3; ZNF334; MEN1; ARID4A; BRD7; WIZ; ZNF430; PIAS3; RCOR3; ZNF23; BAZ2B; PAX5; RBM14; ZNF45; GTF2IRD1; HIVEP2; ZNF764; NCOA4; OLIG2; ZBTB14; MAGED1; HIPK3; ZNF506; NCOR1; PURA; RBBP5; KDM4A; CRY1; CENPF; TBL1X; RCOR1; SUV39H1; HMBOX1; ZNF177; EP400; ZMYND8; NCOR2; TSC22D1; ZFP64; CTCF; SNIP1; ZKSCAN5; FOXO1; ZNF282; SATB2; ZSCAN16; TULP4; FOXN3; ZHX2; TAF10; CDK8; PITX2; WHSC1; LPIN2; MED6; MED13; E2F3; TADA2A; MYCN; EGR3; ZNF93; JARID2; NHLH2; UBE2I; NFYC; SMAD2; EZH2; ERBB2; EDF1; PKNOX1; KDM2A; ING3; MYRF; RNF138; CLOCK; LZTS1; ZNF131; LEF1; SMARCA4; CDYL; NFYB; ASH2L; ZNF562; MLXIP; TEAD1; TBL1XR1; IRF2; SAP30; MLLT10; ZNF281; ZNF783; ZBED1; KMT5A; RERE; SPEN; ZMIZ2; ZBTB39; ASCL1; TAF9B; CTNNB1; FOSL2; ZFHX4; BTAF1; RBBP7; TSC22D2; IKBKAP; MEOX2; ZNF143; BPTF; CITED1; BMI1; ZNF711; UBE3A; FUBP1; BATF; ING2; ZNF302; NCOA6; FOXO4; ZNF12; HIC2; PPARGC1A; ING1; GMEB1; YBX1; PREB; SMAD5; ATF4; TRIM28; SOX5; GATAD2A; INSM1; ARID3B; ZBTB20; MYCBP; ZNF587; BTG1; BCL3; SF1; ZNF672; MED24; ELK3; ZNF124; ENO1; PRKDC; BCL10; MEIS1; ID4; TRIM22; SOX10; ELK1; UBE2B; ZNF212; BBX; SERTAD2; NRBF2; ZNF721; TGIF2; DACH1; RNF111; HDAC2; AFF1; ZMYND11; ZNF43; NELFB; NFAT5; HDAC1; PAX6; CERS6; PHF8; ZNF211; DDX54; ZNF426; CCNT1; ZNF44; FOXC1; ABL1; CREG1; CBFB; NFE2L1; CNOT6; HOXC6; ZBTB16; NFATC1; ZNF419; WWTR1; ZNF551; ELF5; ZIC1; ZNF266; MAF; DDX5; CHD4; ZNF148; ZBTB43; ZNF217; POU4F1; TSG101; CCNE1; NRIP1; DNAJC1; NKX3-1; SMAD1; FLNA; ID3; HLF; PBX1; CARM1; DNMT3B; CREB3L2; ZBTB38; SIAH2; ETS2; XBP1; ID1; HMG20B; ZNF586