Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79732 Plumbagin GSE92742 FIBRNPC Human 6h 10uM EID0474
Types Number Response transcription factors
Up-regulation 131 HES1; NFE2; EGR1; FOS; CSDC2; DDIT3; GATA2; WT1; GATA6; CEBPE; SPDEF; ZNF274; THAP7; CERS4; KDM5C; NKX3-1; ST18; SOX2; ZNF205; TAL1; TAF5L; ID4; CBFA2T2; ZNF136; ZNF85; RSF1; JUN; MED14; NAB2; KLF4; ZNF331; AIP; JUNB; FOXG1; MYCL; ZNF117; CD3D; ZNF43; NKRF; HLF; HOXD1; PNRC1; ELF3; EGR3; MAFF; HDAC5; MYC; HOXB1; MED17; ATF3; ID2; NFATC3; RORA; RBM39; SSBP3; KLF11; NEUROD6; IRF9; CREB3; TOX3; PBX3; ZNF195; HIC2; MXI1; ZNF32; ZNF232; HOXB2; ZFP36L1; ZNF415; IFI16; NR4A2; MYBL2; MED15; IRF6; ZNF91; PKNOX2; PCGF3; KLF10; HIPK2; FOSB; MAFB; SOX9; VDR; FOXA1; HHEX; PEG3; PFDN5; MYRF; DNMT1; SMARCA1; CUX2; TRIB3; ZNF44; ZNF239; ZNF665; JUP; NR4A3; NR4A1; PAWR; NR1H2; SALL2; NANOG; ID3; IRF1; ZNF423; LIN28A; SOX13; TP63; ZNF124; ZFPM2; NFKBIA; DLX2; BCL6; MNDA; MEIS2; NFKBIB; CRYM; BHLHE41; VPS72; INSM1; SSX1; ERBB4; CDK2; ESR1; MYBL1; CTBP2; TBX3; EHF; ARID5B; ZBED2; HOXB6
Down-regulation 119 KDM5D; RUVBL1; CCNA2; TRIM16; MTDH; RCOR1; ZFY; BASP1; SUV39H1; PARP1; UBP1; ZNF189; FOXO3; TLE1; WWTR1; NUP62; ADNP; USP22; NFIB; LIMD1; SMARCA4; SUB1; FOXJ3; BMI1; CBX3; TRRAP; BCLAF1; RNF6; MED24; REST; ATF1; SNW1; TCERG1; HLTF; TCF12; NCOA6; CENPF; BLM; RUVBL2; SMAD2; TRIP6; ATF7IP; EZH2; ELF1; HMG20A; FOXN3; CTR9; SMAD3; NRIP1; HTATIP2; TSC22D2; YWHAB; ZFHX4; BRD3; ZMYND8; TADA3; HMGA2; BRPF1; ENO1; SETD3; PAX5; TLE2; TFEB; PPARGC1A; NR2F2; ZEB1; ZBTB38; ELK3; SFPQ; STAT5B; TLE4; ZHX3; SREBF1; HNRNPD; NFATC1; ERBB2; SLC2A4RG; ARID4A; TULP4; STAT3; CBFB; RNF4; RNF141; RBM14; BATF3; HEY2; CCNC; FOXD1; ZBTB20; NELFB; CHD1; HEY1; ZEB2; CRY1; MYCBP; RBPMS; TSC22D1; RNF10; MAF; PTRF; MEF2A; HOXA5; FOSL2; MED1; PAX6; MAGED1; NCOA1; KLF9; NFE2L1; HIPK3; BCL11B; PURA; ZIC1; HOXC6; TBL1X; MSX1; HOXC10; MNAT1; CRK