Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79633 Diaminoquinazoline GSE92742 FIBRNPC Human 6h 10uM EID0473
Types Number Response transcription factors
Up-regulation 83 KDM5A; HDAC3; NEUROD1; VPS72; EGR3; KLF10; NEUROD6; NFIB; NR5A2; ETV1; PRKDC; ZNF202; MEOX1; MNT; RORA; MYT1L; BCL10; PLAGL2; SF1; NAB2; TFCP2; INSM1; BCL3; ZFPM2; ZNF410; FOXJ2; GATAD2A; ZBTB7A; ACTL6A; ZBTB16; BCL6; DDIT3; VDR; CNOT2; KLF7; WT1; CTBP1; FOXM1; MAX; SOX9; CHD4; NR2F2; SIX2; ARNTL2; TAF6; CERS4; SOX11; PBX1; UBP1; CHD7; TCF7; HMGA1; IKZF1; SIX1; FOXG1; MEIS2; ZNF304; KLF13; ZMYND8; GTF3A; PRRX1; ZFP36L1; NR2F1; EGR2; NR1D2; NRIP1; MEOX2; ZNF226; PAX5; MAGED1; JUND; NR2F6; PEG3; TWIST1; FOSB; KDM5D; MAFB; MSX1; MECOM; TSC22D1; CRK; PUF60; ZNF586
Down-regulation 106 ZNF146; KMT2B; IRF5; ZBTB25; ZNF165; HMGB3; BARX2; FOXF2; SOX4; USF2; TAF5; LMCD1; ZNF692; RUVBL2; YBX1; BTAF1; PSIP1; DPF2; BTF3; SAP30; SALL1; TSC22D2; CBFB; PHIP; PURA; AFF1; MED20; ARID4B; BATF; ZEB1; ZFHX3; FOXC1; BLM; TGIF1; TFEC; MZF1; ADNP; COPS2; HSBP1; ID3; CSDE1; FLI1; MYB; REST; PITX1; ZNF652; NFATC1; MYCL; HTATIP2; ZFP36L2; TLE2; MED13; ZBED1; MITF; ERG; JAK2; BRD2; ZNF443; TBL1XR1; ZSCAN16; CRY1; ZBTB1; PTTG1; AIP; CDYL; SOX10; TBX2; POU4F1; HLTF; LYL1; IRF4; ZNF302; MYCBP; BAZ1A; ZMYM2; TRIM29; HMGB2; ZNF544; REL; CCNC; BAZ2B; SUV39H1; CALR; CREM; HMG20B; CARHSP1; ZNF44; SMAD7; RBBP8; RUNX3; RBPMS; ZSCAN18; SATB2; TXNIP; FOXJ3; EMX2; CD3D; MEF2C; PAWR; MXI1; FOXF1; POU2AF1; GATA3; DACH1; TCFL5; E2F2