Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79604 Pyrvinium GSE92742 FIBRNPC Human 6h 10uM EID0473
Types Number Response transcription factors
Up-regulation 129 PBX3; KLF3; HABP4; ZFPM2; CAMTA1; HIVEP1; SMARCA2; HEY1; RELB; CHD1; TSC22D4; ZSCAN9; CITED1; PBXIP1; ZNF281; ZNF350; NR1D2; COPS5; ZNF354A; CDX2; MSX1; LPIN2; TSHZ2; CDK7; FOSL1; MAFF; TGS1; ZNF136; SOX17; TCF15; SMARCC2; RELA; BCL3; ETV6; CCNE1; MGA; CNBP; TCEA1; HMGXB4; HES1; CEBPD; EYA2; ASH2L; ELF3; ZNF552; DDIT3; BCL10; ZNF32; CREB3L1; PFDN5; FOXF2; ZNF93; BARX1; DDX17; PRKDC; ZNF415; JUNB; MECOM; ETS1; CBX7; ZNF813; SP140L; MYBL1; CHD7; NFKBIA; SIX1; C1QBP; DLX5; FOXJ1; ACTL6A; ZNF593; FLI1; ATF3; NKX2-1; MYC; SOX11; IL16; NR4A3; ZNF43; PRRX1; VGLL4; NAB2; SMAD1; XRCC6; MXI1; TLE2; TRIM22; NR3C2; RCOR3; EHF; HOXB7; KAT2B; ZBTB38; PEG3; ZNF331; DNAJC2; PSMC3; IFI16; E2F3; EMX2; NKX3-1; TRIP6; FOXO1; JUND; CIR1; TP63; SP100; ID3; HMGA1; ZSCAN18; CTNNB1; FOXJ3; NR4A2; ZNF394; CREM; HOXB6; DACH1; ZBTB20; EGR2; BHLHE41; ASCL1; HMG20B; RUNX1; ZNF586; TBX2; SOX9; NR2F6; LEF1; CRK
Down-regulation 121 SOX4; EP400; ZMIZ2; ZNF573; SOX3; MYCN; CITED2; RBM14; MED7; SAFB2; HOXC10; KLF10; TFEC; TAF5; HTATIP2; JARID2; ZBTB1; ZNF324; SNAPC4; PPP1R13L; SREBF2; MYB; RBPJ; MED23; POU5F1B; SMAD2; PPARGC1A; BTAF1; MAFB; NUP62; NFYB; BRD2; SAP30; KLF4; MITF; FLNA; INSR; CUX2; SREBF1; BRIP1; KLF6; WDHD1; RNF10; DMTF1; PIAS3; PBX1; TOX3; ZNF292; UBTF; POLR2A; PKNOX1; FOXE1; NCOR2; TRIB3; DNMT3B; ZNF107; MZF1; PAWR; MED12; TCF7L2; MLLT10; ZNF423; CARM1; CHD8; MAFG; OSR2; RARA; NAB1; TSC22D2; NPAS2; HLTF; REST; MEIS1; HOXA5; CBFA2T3; INSM1; CHD9; ZNF580; NR1H3; SP3; MLXIP; BMI1; ESR1; TRPS1; LIN28A; PLAGL1; EGR3; NR2F2; PSPC1; RUNX3; SATB2; PAX5; PCGF2; NLK; CCNC; IRF8; STAT5A; PTTG1; FUBP1; TCF4; ZNF544; ZNF721; FOSB; WWTR1; ZMYM2; TRIM29; IRX5; JUP; TAF9B; RBPMS; BASP1; SUV39H1; ETS2; NFKBIB; TCFL5; HOXC6; GATA6; IKZF1; GATA3; E2F2; MAGED1