Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79600 Plumbagin GSE92742 FIBRNPC Human 6h 10uM EID0473
Types Number Response transcription factors
Up-regulation 249 TFAP2A; CEBPD; CEBPZ; MYBL2; BNC2; ZNF350; SOX2; SPDEF; ZNF467; HOXB1; ZNF667; DNMT1; SOX3; ZNF141; ZNF257; SALL2; GBX2; FHL5; PBX3; POU6F2; NR2C1; ZNF682; NEUROG2; ILF2; ZNF331; FOXF2; CNOT3; TDP2; JUNB; GMNN; BARX1; ARNT2; TP53; ZNF132; CBX2; ZNF430; LHX3; ZNF816; ZNF749; ZNF112; PRDM14; ZNF334; ID4; HES1; HEY1; ZNF214; MXI1; IRX4; ZNF552; POLR3C; TP63; SOX13; POU1F1; ZNF835; POU4F3; ST18; TSHZ2; NR5A2; IRF9; SOX15; ZFPM2; NKX2-1; ZNF76; THRB; SCRT1; CSDC2; CTBP2; NR1H2; RSF1; TP73; MLLT1; CDIP1; ZNF287; ZNF224; PBX1; PRDM2; VPS72; PSMC3; ZNF274; PFDN5; ZNF695; FOXE1; ZNF85; CHD2; LMCD1; ZNF304; ZNF268; ERBB4; HBP1; IRF6; ZNF43; SOHLH2; WWP1; ZNF74; RORA; FOS; MEF2C; PRDM12; TTF2; ZFHX3; ZNF415; FOXN3; YEATS4; KLF15; E2F8; ZNF444; TCF3; NANOG; ETS1; FLI1; GTF2A2; E2F1; THAP10; E2F2; ZNF492; TBX1; KLF3; SOX18; HOXD1; THAP7; ZNF345; ZNF91; CITED1; ZNF571; ZNF232; PHIP; ZNF136; SOX17; TGFB1; BNC1; ZNF273; MYBL1; CREB1; ATN1; FOXG1; AIP; IFI16; CBX4; ZNF215; ZNF155; ZNF623; PIAS4; COPS2; NR2E1; FOXA1; COPS5; DLX4; CALCOCO1; CREBL2; BRF2; ZHX2; ZNF180; ACTL6A; GATA2; ZNF93; YEATS2; PEG3; GATA6; CDK2; SOX11; ZNF528; ZIC3; ING4; ZNF426; MEIS2; ZNF12; TERF1; WWC1; SIX3; CBX6; TCF21; TGIF1; ZNF394; AES; HMGB1; DLX5; TLE2; DNAJC2; SUPT5H; BLZF1; PIAS1; ZNF551; PRRX1; CEBPG; ELF5; SMAD1; TRPS1; ZNF83; KLF9; LIN28A; TCEA1; NR4A3; ISL1; WNT4; MNDA; HOXB5; SIM2; ZNF219; TCF7L2; HMGB2; PEX14; ZNF665; DMTF1; ZNF419; ZSCAN18; DLX2; INSR; TRIM22; XRCC6; MECOM; CTNNB1; CREM; ZNF264; FOXO1; HDAC9; ZBTB16; SP100; HHEX; CBFA2T3; SMARCB1; MAFF; ZNF544; VDR; KAT2B; ZBTB20; TFAP2C; MITF; TWIST1; ATF3; RBBP8; PAWR; SUV39H1; MEOX2; CSDE1; EMX2; POU2AF1; SNAI2; JUND; DACH1; BCL11A; ZNF586; JUP; NR4A2; TBX3; KDM5D; FOXF1; ASCL1; BHLHE41; ID1
Down-regulation 287 SMARCA4; SLC2A4RG; FOXO3; CCNA2; EDF1; DDX54; NFIL3; RHOA; MED1; HIVEP2; NUP62; ZNF764; ELF1; USP22; HOXC6; ERBB2; KAT7; JARID2; USF2; ING2; TSC22D2; DR1; TLE1; HMG20A; BMI1; ARID4B; TCERG1; SMAD3; TBP; PSMD9; KLF10; TFDP1; ELK1; GABPB1; HSBP1; ATF7IP; PHF2; EP400; CENPF; TRIM32; POLR2A; ZMIZ2; KMT2B; ZBTB14; KDM2A; BIRC2; FOXD1; SCAND1; SMARCD2; TADA3; NR2F2; AGO2; TAF10; PKNOX1; PCGF2; BATF3; KDM4A; RBM14; MAZ; RELB; NELFB; HOXA7; KDM5A; ZNF189; C1D; RFX5; CTR9; YWHAB; MLX; ATF6; IRX5; SIAH2; ZNF384; KLF6; ARID4A; ZBTB24; GMEB1; ATF1; BCL10; TBL1X; PURA; NEDD8; ECD; PSPC1; CARM1; KAT5; HOXC4; SREBF2; HOXC10; ZZZ3; ZNF629; BRD2; NRF1; PDLIM1; GATAD2A; MTDH; ID2; SMARCC1; CARHSP1; MEF2A; TAF4; ADNP2; SERTAD2; RAN; RXRB; TCF7; SFPQ; VEZF1; BAZ1B; LPIN2; TRIM16; HLTF; ZFP64; MED24; HIPK3; NCOR2; HOXB9; MLLT10; SKI; SSRP1; BCLAF1; GMEB2; PRRX2; ZBTB1; GTF2IRD1; SMARCD1; TOPORS; CHD9; BRD8; FOXC1; UBP1; ZNF672; SUPT4H1; SATB1; MLXIPL; HDAC6; NR2F6; STAT5A; ZNF226; NRBF2; UBE2I; BRPF1; BATF; SOX4; FOSL1; MNAT1; KLF12; ASXL1; HSF2; MED23; ORC2; NCOA6; ZBTB18; CRY1; MKL2; TRIB3; ZBTB11; MSX1; REPIN1; GABPA; STAT3; SNW1; NCOA1; TOX3; CREBZF; WHSC1; CBX3; ERG; BACH1; ZNF45; HTATIP2; SUB1; ING1; SIX2; SIN3B; UIMC1; NRIP1; RNF6; NPAT; ZNF267; SAP130; BBX; YBX1; ZNF143; DNMT3B; NAB1; ZNF146; HOXD9; TAF1D; NR1I2; HOXB7; DNAJC1; TERF2; HNRNPD; MAX; MED6; PLAGL2; TULP4; FOXJ3; BRD3; EP300; CCNC; SMAD7; SAFB2; ZNF263; ABL1; ZBTB43; NFAT5; REST; IRF7; BRD7; ALX1; EZH2; PIAS3; NFATC1; BTG1; NFKB1; NR3C1; MKL1; SREBF1; SAP18; SMARCE1; MSC; ZEB2; HMBOX1; ZNF84; SIRT7; CENPB; PMF1; RNF141; MXD4; CBFB; HMG20B; CUX1; NPAS2; CITED2; ZNF443; SSX1; NFE2L3; PITX2; HOXD11; BCL3; ETS2; SF1; IRF8; SIX1; HMGA1; PTTG1; ENO1; ELK3; PHF20; TFEB; HDAC4; IKBKAP; TSC22D1; NFKBIB; RNF14; RUNX3; SP2; PNRC1; MAGED1; SATB2; YAP1; RARA; FOXL2; RCOR1; ARNTL2; FOSL2; STAT5B; EGR3; MAF; FUBP1; RNF4; ZMYM2; CD3D; MYRF; TCFL5; MEIS1; LEF1; GATA3; MAFB; FLNA; ITGB3BP; SOX9; WT1; CRK; IKZF1