Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID79515	Acadesine	GSE92742	FIBRNPC	Human	6h	10uM	EID0473

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	ZNF131; ZNF91; HLF; TFEC; ZNF573; FHL5; BCL6; PRDM4; ELF2; ZNF8; ZNF571; SAP18; CDIP1; E2F2; CREG1; SND1; ESR1; NANOG; IFI16; HDAC7; TEAD3; TBL1X; PIAS1; ZNF148; DDX17; PPARGC1A; TRIM24; RNF111; HIRA; TRIM22; PRDM2; ZNF281; ERG; SOX12; ING4; BRPF1; REL; MED20; ZNF606; EMX2; SMARCA5; SMARCA1; TRIM27; RBPMS; MED14; ZNF667; SMAD1; E2F8; TAF1D; MAFF; TGFB1I1; NR1H4; PCGF3; GLI3; ZNF516; ZNF85; ZNF304; EYA2; ZNF544; ZEB1; CDK8; UBE2I; NR2C1; ZNF23; POU5F1B; PLAGL2; ZNF629; NFKBIA; BASP1; MBD2; MED4; TRIM32; HMBOX1; TSC22D2; ZNF512B; EP300; NEUROD1; SMARCA2; SUPT4H1; ZNF248; NFX1; ZNF83; NKX3-1; NFATC1; MECOM; FOXN3; AR; HOXD1; TCF4; SALL2; JUNB; ZSCAN16; TCF12; TRIB3; ELF3; PRRX1; FOXO1; TFAP2C; IRF6; NFE2L1; NFE2; CREM; ELK3; ZNF117; SMAD6; NR4A1; LIN28A; SUV39H1; BAZ1A; ZBTB20; NR1H3; PBX1; ZBTB38; IKZF1; ZNF551; ATF3; SERTAD2; BCL11A; ID3; NFATC3; HMG20B; MXI1; ID1; NR2F6; CRK; DACH1; ZNF586
Down-regulation	149	DNMT1; SP110; LMCD1; HIPK3; TMF1; HLX; HMGB3; C1D; THAP1; SIX2; MLX; HTATIP2; VDR; AATF; RRN3; ELF4; IRF9; THAP7; GMEB2; PRKDC; HSF1; CHD3; SF1; IKZF5; CENPF; PUF60; ZNF528; MED1; LITAF; GTF2IRD1; MYT1; PIR; ARID4B; PHF2; PBX3; ZBTB1; MNX1; SUZ12; AES; OSR2; AGO2; GABPA; BCL11B; ZNF557; ZNF692; STAT1; SOX13; SNAI2; PCGF2; TFDP2; NR1H2; IRF3; ISL1; MLXIP; RNF138; MYNN; LDB1; ETV5; MTDH; ZNF140; SRCAP; ADNP2; ZNF468; DPF2; ZNF200; RAD21; SATB2; PTTG1; NFKB1; OVOL2; ZNF593; NFE2L2; ZNF266; HOXC6; HSF2; WNT4; ZNF432; ADNP; KLF4; MAF; MAFB; SUPT5H; CERS6; IRF7; MYC; BLZF1; TRIM16; ZNF195; FOXD1; HDAC9; CD3D; C1QBP; NKX2-2; ARNTL2; ZFP36L1; TAF10; ZNF24; CREB1; ENY2; YWHAB; PHF1; PSMC3IP; CRY1; EGR3; ZNF124; CERS4; NFRKB; HEY1; FOXC1; BAZ1B; CCNE1; CNBP; STAT4; POU2AF1; SMARCD3; JUND; DDIT3; ETS2; CTBP1; CHD7; TBX2; STAT5A; FOSL2; RCOR3; MYRF; KLF5; HMGA1; KLF13; VEZF1; SMAD7; ZEB2; ZNF721; ASCL1; BMI1; HOXB7; FOXG1; SSX1; AEBP1; IKBKAP; FOS; KLF2; BRD4; LEF1; TOB1; FLNA; GATA3; TBX3; NFKBIB; TCFL5