Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID79502	Isotretinoin	GSE92742	FIBRNPC	Human	6h	10uM	EID0473

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	ZNF131; FHL5; RORA; KDM5A; CEBPZ; ABT1; MEOX1; ZBTB16; ZNF202; HIRA; ZNF281; CBX6; PIAS1; ZFPM2; TP63; CAPN15; RBPJ; ZNF232; THAP7; ZNF24; ADRB2; CNOT3; NKX2-1; EBF2; SND1; MEF2C; BRCA2; BAZ2A; AIP; CEBPD; USP16; AES; IFI16; HCFC2; CALCOCO1; MED15; SMAD5; MAFG; ST18; DAXX; CSDE1; BATF; UBE2L3; MYBL1; BCL3; BCL6; TAF5; BBX; ID4; VDR; KMT2A; ISL1; TTF2; PCGF3; ZNF467; GFI1; KLF4; ZBTB7A; JAK2; MEIS2; MAF; ARNT2; MLLT10; MXI1; SUPT5H; INSM1; LHX6; LZTR1; ARID5B; HLF; COPS2; HES1; SMARCB1; MAFB; FOXM1; PBX3; MBD2; KLF2; PITX2; RXRA; ZNF580; DNAJC1; PEG3; KLF9; CREB1; PBX1; NEUROD1; TRIM22; ELF5; TCF7L1; ARNTL2; CXXC1; XRCC6; CARM1; SOX11; YEATS2; GTF3A; TCF4; NFATC3; SMAD4; PTTG1; SP100; PAX6; KAT2B; LIN28A; ZEB2; CITED2; ZNF423; SUV39H1; ATF4; HMG20B; GATA3; SNAI2; CREM; ZBTB38; TBX2; MEOX2; TBX3; NR2F6; CRK
Down-regulation	178	ZNF764; ADNP; HIVEP2; KLF1; CNOT6; MYB; TP53; CDK9; SLC2A4RG; BATF3; SSRP1; AGO2; RUVBL2; ZNF512B; HEY2; ZNF350; ARID4B; BIRC2; RELA; ZKSCAN7; AEBP1; HMGA2; ERG; ZMIZ1; ZNF432; PATZ1; PIR; ZNF146; ARID4A; MED1; BASP1; GON4L; CENPF; HLTF; TADA3; GATA1; NFYA; MXD1; NPAS2; HOXA7; ZNF606; ZNF7; SFPQ; GATA2; TLE1; HOXC10; PAX2; CBFB; ZNF177; TRIP6; TAF4; TAL1; ZNF556; ZNF544; ADNP2; HSBP1; ZNF16; ABL1; HOXC6; PRKDC; CUX1; PPARGC1A; PSIP1; RUNX3; PRMT2; MED20; NLK; KLF10; HOXB13; LPIN2; CRY1; ZNF329; AFF1; SP3; BCLAF1; THAP11; CDK8; RAD21; REST; CBX5; DNMT3B; ZNF529; PUF60; PURA; GFI1B; ZNF468; PITX1; NFIX; ZNF302; MTDH; KAT7; PRPF6; MAZ; ELF3; TERF2; BAZ2B; GTF2F1; SMARCA5; TRPS1; SATB1; ZNF629; RRN3; LEF1; ZNF184; NCOA2; ZNF134; MKL2; HDAC5; NRIP1; RCOR1; ZNF43; MYC; TRIM16; MLXIP; ZNF83; TCEA1; JARID2; ZNF443; NKX3-1; SIM2; MECP2; TSC22D2; BHLHE41; HOXA10; EHF; LITAF; ZSCAN18; ZBTB18; C1QBP; CHD7; RYBP; NFKB1; IRX5; ESR1; SMARCA1; ZNF217; ZFP36L2; ZNF266; ZNF44; ZNF226; ELK3; NAB1; CTR9; ATF3; POU4F1; FOXC1; TAF10; CALR; YWHAB; SMAD1; FOXF1; RNF6; FLNA; EN1; NR3C1; MSX1; DDX5; TXNIP; TWIST1; TCFL5; FOS; RUNX1; FOXJ3; MYRF; ID3; STAT5B; SATB2; RBPMS; PAX5; NR4A2; WWTR1; HOXB7; BCL11A; E2F2; ETS2; WT1; ZIC1; ZNF586