Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79498 Diaminoquinazoline GSE92742 FIBRNPC Human 6h 10uM EID0472
Types Number Response transcription factors
Up-regulation 46 NR1H4; FUBP1; TRIM29; TAL1; TGIF2; ZNF654; HOXD1; PROX1; ARNT2; BHLHE41; TFAP2C; MAF; SSX1; CAMTA1; NR5A2; AEBP1; KLF5; ZNF281; TEAD4; TP63; INSR; ATF5; ERG; PITX2; NFAT5; ZNF131; BACH2; YBX3; SPEN; TAF1D; FOXA1; GATA2; TBX3; FOXO1; HEY1; IRF6; KDM5A; SOX2; HHEX; ID1; NKX3-1; MEIS2; NRIP1; HES1; ST18; NR2F6
Down-regulation 59 TSC22D3; ZSCAN18; ERBB2; NUP62; SIAH2; ZNF84; ZNF148; MEF2A; ZNF652; CREB3L1; HOXC10; RNF6; HDAC2; PPARD; ING2; HLTF; SIX1; TSC22D1; ZNF329; ZNF426; ZHX3; RNF4; RBBP7; NRBF2; CBX7; SMAD7; KLF10; ZNF544; ATF1; BIRC2; TCF12; TFEB; PIAS2; SIX2; SMARCA2; TOB1; ARID5B; ZNF430; BMI1; HMGB3; CRY1; ELF5; STAT3; RFX5; KLF6; MEIS1; ZNF91; EMX2; SSBP2; TGIF1; SATB1; ZBTB38; TWIST1; PLAGL1; ETV1; STAT1; KDM5D; ZBTB18; FOXO4