Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79468 Purpurogallin GSE92742 FIBRNPC Human 6h 10uM EID0472
Types Number Response transcription factors
Up-regulation 158 PRDM14; ZNF232; ZNF117; POU2AF1; TFAP2C; NFATC3; DLX2; FOXF2; ZNF345; TFAP2A; ZNF611; ZFP69B; ZNF141; PRDM1; ZNF652; TP73; ZNF573; ZNF180; NR5A2; MYBL2; ZNF224; ZIC3; HOXB5; NR1H4; HEY2; FEZF2; SOX3; ZNF589; ZNF133; SOX18; KLF11; ATOH1; BNC2; SIX3; ZSCAN32; PAX5; ZNF423; POLR3C; LIN28A; DLX5; NANOG; TRIB3; MEIS2; TCF7; ZNF33B; BARX1; TCF7L1; NOC2L; TDP2; ZNF500; ZNF544; IRF6; ZNF85; MYBL1; CERS4; FUBP1; CDIP1; LHX3; PHIP; CHD8; PSMC3; NR2F1; SOHLH2; ZNF235; ZNF93; ZNF665; CXXC1; IRF7; TGIF2; SALL2; HIRA; IRF3; TULP3; ZNF426; ERBB4; ZNF264; BCL11A; CREM; ZNF334; ZNF512B; HBP1; HOXA1; SOX13; ZNF160; GATA6; TEAD4; HOXB6; SOX10; ARNT2; POU5F1B; ID4; SUPT3H; TFDP1; CTBP2; KLF5; ZNF12; ZNF415; SLC2A4RG; HIC2; BHLHE41; ZNF91; FOXO1; ZFPM2; AEBP1; HOXB2; E2F8; RAD21; HOXB7; SOX9; PAXBP1; ZNF124; XRCC6; TCEA1; PAX6; MXI1; HES1; ZNF43; EN1; ID3; SOX11; PBX3; PRPF6; REL; ZNF34; PAWR; NFATC4; FOXG1; SNAI2; NFE2L3; NR2F6; NR1H2; TGFB1; FOXF1; CAPN15; ID1; PBX1; MNDA; SOX17; ECD; FOXE1; OSR2; TWIST1; HEY1; IRF9; HOXD1; MAFB; BACH2; NKX2-1; HHEX; WWC1; ST18; SOX2; MYCN; PEG3; CEBPD; DMTF1; ATF3; DACH1
Down-regulation 220 USP22; HOXA10; NFKBIB; TBPL1; PHF2; LPIN2; ATF1; CBFB; SETD2; TRIM32; NUP62; PRRX2; CCDC59; BRPF1; CREB3L1; UBP1; SIAH2; MAGED1; MEF2A; SMARCA5; YBX1; RBM14; BCLAF1; HSBP1; EP400; IKBKAP; RNF6; SMARCA4; YAF2; VGLL4; DDX54; BMI1; PPARG; ZNF23; PURA; CTR9; E2F3; ZHX3; ING1; ZBTB11; SAP18; HDAC7; BCL10; STAT5B; HOXC6; PKNOX1; BRD2; HABP4; SMARCA2; MGA; TCF12; KAT7; BAZ1B; RELA; CCNT1; PSPC1; ZNF783; ING3; ELK3; SMAD2; ELK1; STAT5A; CBX3; MXD4; BBX; ORC2; NPAS2; TRAK1; FOXJ1; TAF10; FOXD1; ZNF148; BRD8; KDM2A; ATF6; HOXC10; BRD3; TADA3; NAB1; BASP1; MYT1L; ZEB2; BAZ2B; KMT2D; HIVEP2; USF2; HDAC5; ZNF432; TSC22D1; NFYB; ZMYM2; PATZ1; SIX1; SSX1; SP3; SFPQ; ZBTB1; BCL11B; ZMIZ2; TMF1; PHF8; ZNF468; RHOA; DNAJC1; KLF12; MSX1; MAFF; ZBTB38; TRIM28; FLI1; DDX5; KMT2A; ZNF672; ZNF189; ZBTB24; RNF4; NKX3-1; MAX; ELF1; ELF2; CHD3; ZNF281; PCBD1; ZZZ3; ARID4A; MSC; AFF1; IRF2; HDAC6; JARID2; RUNX1; HLTF; ZNF226; NFKB1; RCOR1; IFI16; SMARCD2; PBRM1; ZFP64; ARID4B; NFKBIA; NCOA4; BAZ1A; YWHAB; STAT6; TSC22D2; PIR; RNF10; NFATC1; ITGB3BP; NR1D2; BATF3; FOXJ3; ASH2L; EDF1; FOSB; CRY1; CDK8; MED1; TRIM27; ELK4; REST; NFYC; NELFB; SFMBT1; BATF; CBX5; KLF2; VDR; PIAS2; UBE2B; BRF2; NFIC; KAT5; MED24; HTATIP2; GABPB1; ETS2; NR2F2; MYB; TAF7; SNW1; MED23; HCFC2; LIMD1; RELB; TP53; TSC22D4; PDLIM1; BCL6; HMGA2; ABL1; SAP30; DEAF1; ASCL1; NFIL3; GATA2; HOXA11; OLIG2; KDM5D; ENO1; CITED1; SREBF1; FOSL2; STAT1; FOXA1; CEBPA; ZBTB18; TBL1X; KLF6; MYCBP; HMGB2; HMGB3; HLF; PITX1; NR3C1; EYA1; FOXO4; THAP11; SMAD3