Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79465 Plumbagin GSE92742 FIBRNPC Human 6h 10uM EID0472
Types Number Response transcription factors
Up-regulation 223 NFATC3; ZNF117; ZNF141; ARID3B; PRDM14; FOXF2; EGR2; ZNF232; TFAP2A; ZNF536; TCF3; ZNF195; ZFP69B; HESX1; ZMYM2; ZNF219; ZNF202; TDP2; SALL2; SOX9; CSDC2; E2F5; ZNF345; GATA6; ZNF682; SPIB; SOX3; CREM; TCEA2; MED14; NR5A2; CDIP1; NR3C2; ZNF180; ZNF573; ZKSCAN3; NR4A2; ZNF33B; TP73; HOXA1; CHD2; MKL1; PRKDC; TCF7; LHX3; ZNF623; FOXM1; HOXB13; ZNF589; NRBF2; MYBL2; ZFPM2; ATOH1; CERS4; NANOG; E2F4; ILF2; DLX2; TAF9; MED12; CBX2; WDR77; NR2F1; ZXDC; RAD21; THRB; TERF1; L3MBTL1; TTF2; TFAP2C; SOX13; TCF7L2; ECD; ZNF711; KLF3; DNMT1; TGIF2; MBD1; ACTL6B; CUX2; GTF2I; ZIC3; NFE2L3; YEATS4; LIN28A; ZSCAN9; PEG3; FOXO1; E2F8; ZBED1; PAWR; BCL11A; RARG; HOXB5; HMG20A; ZNF268; TAL1; TRIB3; POU2AF1; DAXX; ZNF415; ZNF75D; ZNF112; TEAD4; JUNB; POLR3C; ARID1A; ZNF93; JAK2; HEY2; CNOT6; TBX3; WNT4; KLF15; HOXD1; GLI1; ZNF43; HIRA; KLF1; TAF1A; SOHLH2; BNC1; XRCC6; RFXANK; FOXF1; ZNF85; RBBP8; SNAPC4; SIN3B; COPS5; ZNF223; ZNF350; ZNF12; ETS1; NR5A1; TCF7L1; TFDP2; TP63; ZNF140; MEIS2; ZHX2; ACTL6A; ZNF235; ZNF200; ZNF334; NR0B1; ZNF516; MNDA; PCGF3; ERBB4; BCOR; IRF6; ATF3; ZNF580; HIC2; TRIM24; ZKSCAN5; HEY1; FUBP1; SMAD4; GMNN; ARNT2; ZNF423; BHLHE41; GFI1B; WWTR1; ID3; SMAD3; HBP1; ZNF331; NPAS2; RNF138; SOX17; PKNOX2; ETV4; ID4; BRIP1; BRWD1; TRIM29; TAF4B; GATAD2A; NR2F6; ARNTL2; DLX5; MBD4; YAP1; NR1H2; FOXE1; STAT4; BACH2; FOXA2; EHF; KLF13; RB1; PHIP; TGIF1; ZNF304; TBX21; TCEA1; THAP10; MYBL1; CITED2; CUX1; FOXA1; HES1; ELF5; LEF1; MXI1; ZNF217; OSR2; TGFB1; DACH1; NKX2-1; MYRF; REL; CD3D; CEBPD; THAP11; HOXB6; ID1; ST18; DMTF1; TOX3
Down-regulation 263 ZMIZ1; HOXA10; TBPL1; ID2; USP22; NFKBIB; FOXO3; KAT6A; NUP62; YBX1; SETD2; FOXD1; TSC22D3; CRK; HOXC10; ELK3; GLI3; BRPF1; RXRB; PRRX2; TRIM32; SMARCE1; NEDD8; HOXC6; MITF; PCBD1; KDM2A; DNAJC1; TBP; MXD4; ING3; PUF60; RHOA; SCMH1; PHF2; KAT5; BMI1; MED24; HSBP1; MLX; NFKBIA; NFIB; SMARCD2; CTR9; ZNF408; ZHX3; PURA; ATF6; ZBTB24; BCLAF1; GTF2A1; PSMD9; NAB1; ARHGAP35; ZNF148; NCOA6; MED1; BRD8; CCNC; SAFB2; BAZ2B; ZNF8; TCERG1; CTBP1; RBPMS; TCF12; USF2; SUV39H1; MAFB; RBM14; KLF11; NFIL3; MAX; MEF2A; BBX; UBE2B; KAT7; MLXIP; CHAF1B; BRD2; GTF3A; DDX54; ZNF652; KLF2; RLF; SSX1; TADA3; PTTG1; SP3; SIX1; BCL3; CBX3; CTNNB1; YWHAB; KLF9; VGLL4; HSF2; SCAND1; AFF1; PBRM1; PMF1; FOSL1; NFX1; EMX2; SREBF1; ING2; ZNF384; MAZ; GMEB2; LHX1; TRIM28; CLOCK; MAGED1; CREB3L1; CCNA2; ZNF337; TCF4; RUVBL2; ALX1; NELFB; CRY1; ZBTB38; BCL10; EED; ORC2; ZNF783; ZNF672; MYCBP; HTATIP2; ZNF473; SNW1; AIP; PCGF2; KMT2A; HOXA11; TAF10; TRAK1; DEAF1; ZNF143; HLTF; NR2F2; JARID2; RBM39; ZFHX4; CERS6; MED6; SLC2A4RG; NFIC; VEZF1; NPM1; PAX8; SFPQ; TFEC; BATF; ATF1; ARNT; NONO; NFIX; RELB; ZBTB1; SMARCA2; FOXJ3; NCOA4; RELA; PIR; ZEB2; ENO1; MYT1L; PITX1; SIAH2; ARID4A; NKX3-1; ING1; SP140L; SUB1; ZNF528; RNF6; LOXL2; BIRC2; AHR; CBX5; SREBF2; TEAD1; YAF2; ITGB3BP; RBBP5; TWIST1; TSC22D1; PHF1; ZMYND11; TMF1; DRAP1; PATZ1; BCL11B; PHF8; HIVEP2; MECOM; KLF6; ZNF410; UBTF; FHL2; NCOR2; LHX6; TRIM16; KAT2B; ETV1; RXRA; SIX2; IRX5; ZBTB18; ETS2; RBL2; BRF2; PIAS2; STAT6; BAZ1A; HCFC2; DPF2; EDF1; BACH1; RNF141; NFATC1; SMAD2; KLF7; SFMBT1; SKI; PREB; ZMIZ2; HMGN3; LMCD1; PSIP1; BASP1; SATB1; KDM5A; MBD2; RYBP; CHD3; SAP18; PLAGL1; ARID5B; HMGB3; TLE4; SMARCA4; PRRX1; NR1D2; TSC22D2; TGFB1I1; KDM5D; ZNF146; HMGA2; STAT1; RBBP4; SAP30; EYA1; MYB; NRIP1; ARID4B; CEBPA; TBL1X; MSX1; FOSL2; CENPF; FOXO4