Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID79440	Tomelukast	GSE92742	FIBRNPC	Human	6h	10uM	EID0472

Response Information :

Types	Number	Response transcription factors
Up-regulation	140	ZNF117; PAX5; TP73; ZNF232; POU2AF1; TCF7; TFAP2C; ZNF219; CBFA2T3; CBX2; MED12; HDAC6; HOXA1; ZNF589; LYL1; PARP1; BHLHE41; CBFA2T2; FOXM1; MYBL2; FUBP1; NR3C2; ZNF160; KLF3; ZNF141; E2F5; CTBP2; TFAP2A; CREM; L3MBTL1; RARG; ERF; MBD1; TLX3; USP21; DLX4; HDGF; DLX2; CREBZF; HOXD3; TRIB3; TERF2; HOXB13; ZXDC; POU4F1; HOXB7; SERTAD2; ZNF580; IRF6; SOX18; WNT4; ECD; ZBED1; MTA1; HOXD1; BNC1; SPIB; ZNF165; CNOT6; TGIF2; MNDA; TFDP2; TULP3; BCL11A; ZBTB20; MEN1; TRIM29; TP63; LHX3; NR5A2; ZBED2; ZSCAN31; GATA6; PEX14; ZNF721; SMARCC2; ZNF467; BACH2; NR4A2; ZNF33B; SUPT3H; ARNT2; ZNF688; ZNF444; NR4A3; ZIC3; ZNF423; ERBB4; PAWR; ZHX2; EHF; AEBP1; HIRA; ELF3; CEBPD; FOXA2; NPAS2; MYBL1; JUP; SMAD1; BCL6; EPAS1; INSR; KLF4; NKX2-1; LMCD1; CBX6; FOXE1; ST18; OVOL2; ZNF331; ID3; MEIS2; FOXO1; KLF5; REL; SOX11; SMARCA1; TOX; IFI16; TAL1; HMGA1; CARHSP1; NFATC4; TBL1XR1; SNAI2; RUNX3; ZFPM2; HHEX; SOX9; TGIF1; ZNF131; CD3D; NR3C1; NR4A1; HES1; NR2F6; HOXB6; ID1; TOX3
Down-regulation	192	HOXA10; ERBB2; BCLAF1; TBPL1; KAT7; ING3; CCDC59; SETD2; MITF; ZIC1; NUP62; CREB3L1; RNF6; TSC22D3; BRPF1; NFKBIB; ZNF468; ZNF23; PHF2; HDAC5; ZHX3; MEF2A; FOXO3; SOX4; IKBKAP; JARID2; NFIX; USP22; VGLL4; CTR9; KLF9; CBX3; ATF6; KDM2A; YBX1; NR2E1; MSC; TBP; RHOA; ZBTB1; PURA; SUB1; ZEB2; CAMTA2; UBP1; PMF1; SALL1; BAZ1B; NEDD8; ZKSCAN1; ZBTB43; ZBTB11; TMF1; ING2; GMEB2; YWHAB; MEIS1; ZNF143; HOXA11; HSF2; BRD2; ARID4A; DDX5; MED1; MSX1; ZNF652; BMI1; HOXC10; ZNF473; PCBD1; ZNF226; MTDH; PSMC3IP; ZNF432; STAT5A; RBPMS; ZNF783; MXD4; HIVEP1; FOXJ3; SP3; RNF4; ARNT; MTF1; BATF3; BLM; SMARCA2; TADA3; SAP18; SMARCD2; HDAC9; NCOA4; SNW1; MYC; BRF2; NR1H2; AFF1; ARID4B; HDAC2; LPIN2; VEZF1; SUV39H1; ZMIZ2; PIR; CRY1; BCL3; MAFF; PHF1; ARID5B; ZNF148; UBE3A; SMARCA4; SSX1; SHOX2; RLF; MYT1L; EZH2; MED24; HTATIP2; TFEC; OLIG2; ZFHX4; ZBTB38; SIX2; ZNF329; TCERG1; PSIP1; MAZ; NFAT5; HIPK2; GATA2; ZNF302; HMGXB4; TCF12; ZNF394; MED6; SMARCE1; HIVEP2; ATF1; BIRC2; NFIL3; ZNF146; MYB; KLF2; FOXD1; REST; ASH2L; RUVBL2; ETV1; CREB3L2; NCOR2; NFKB1; HLTF; CDK8; NFIB; STAT1; HOXC6; FOSL1; WWP1; PHF8; TSC22D2; TRRAP; STAT3; MYCBP; FLNA; EDF1; TRIP6; ELK3; GMNN; SPEN; HMGA2; TP53; TOB1; SCAND1; NR1D2; NR2F2; MAGED1; KAT6B; KDM5D; AHR; NRIP1; PITX1; SMAD3; NCOA2; PLAGL1; FOSL2; ZNF512B; DMTF1; SSBP2; ID4; FOXO4; ZBTB18