Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID79393	Bosutinib	GSE92742	FIBRNPC	Human	6h	10uM	EID0472

Response Information :

Types	Number	Response transcription factors
Up-regulation	151	PRDM14; ZNF117; ZNF232; ZNF611; TSC22D3; ZNF141; TDP2; POU2AF1; FUBP1; ZFP69B; RBFOX2; FOXF2; TRIM29; E2F2; NR2F1; DNMT1; TFAP2A; PBX3; HIRA; ZNF682; ZIC3; SALL2; IRF6; WWTR1; RAD21; ZNF74; ZFPM2; ZBTB20; ATOH1; ZNF589; ZNF500; MYBL2; NR1H4; ZNF44; TRIB3; CSDC2; TP63; DLX2; ZNF580; CTBP2; FOXM1; ZNF345; BCL11A; SRF; MEIS2; MED25; GMNN; CERS4; ZNF652; ZNF573; HOXB5; ZBTB16; TULP3; TCF7L1; MYBL1; ERBB4; TAF9B; MXI1; SOX9; ZNF43; MNDA; LITAF; TCF7; LIN28A; TERF1; ZNF85; NR3C2; HOXB6; NR5A2; SRCAP; SUPT3H; ZNF467; CREM; PSMC3; PBX1; LZTR1; ZNF160; USP21; THAP7; TFAP2C; HOXB2; HOXB13; SLC2A4RG; ARNT2; ZBED2; YAP1; EHMT2; XRCC6; SOX3; ECD; INSR; NR1H2; THAP10; AEBP1; ZNF33B; ZNF12; CRYM; ZHX2; ZNF331; TTF2; TBX3; HES1; MEOX1; DNMT3B; CAPN15; NFE2L3; GATA6; EHF; TCF21; INSM1; SOX11; MDM2; KLF5; HEY1; PAWR; YEATS4; MED14; NANOG; KLF13; HOXD1; AES; RB1; NR4A2; TAF4B; TOX3; ILF2; EGR2; NKX2-1; UBE2I; CUX2; ZNF423; ACTL6A; ZNF512B; PAX6; GRHL2; FOXO1; PHIP; TLE2; NEUROD1; REL; NR2F6; ZNF91; CITED2; BHLHE41; SNAI2; TWIST1; ST18; CEBPD; ID4; SOX2; PEG3
Down-regulation	219	FOS; HOXA10; HOXC10; USP22; SOX4; LPIN2; YBX1; VGLL4; MEF2A; NUP62; PURA; HLTF; SETD2; BRPF1; PRRX2; RNF6; TBPL1; RBM14; FOXD1; BAZ1B; KDM2A; PHF2; STAT5A; TAF10; BCLAF1; GTF3A; ZEB2; BRD2; KAT7; ZBTB1; CRK; IRX5; PSPC1; HSBP1; ATF6; CBFB; CTR9; MSX1; EP400; ZNF23; ING3; ORC2; CBX3; BMI1; CREB3L1; BAZ2B; TBP; NFKBIA; RHOA; SNW1; SMARCA5; STAT5B; MGA; DDX54; ERBB2; FOXO3; KLF2; HDAC7; POLR2A; MLXIPL; ZMYM2; DDX5; TRIM32; ZHX3; MED1; ELK3; IKBKAP; ZBTB38; ADNP; SP3; KLF9; NPM1; HCFC2; USF2; ZNF783; EDF1; ZNF468; CNOT1; ID2; ARID4A; UBP1; SMARCA2; SETD3; NFATC1; NAB1; REST; ZNF148; HTATIP2; HDAC1; ING2; HOXC6; BCL3; BATF; MSC; SKI; ZNF84; TULP4; ENO1; ZNF143; ESR1; ELF1; SMAD2; DPF2; JUNB; RNF14; TSC22D4; SMARCA4; MNAT1; FOSB; TRIM28; MEF2D; NFX1; MAGED1; SALL1; TSC22D1; PHF8; RUNX1; THAP1; SND1; NCOA4; BATF3; GATA3; TFEC; ZNF410; MED6; HOXA11; IRF2; MYT1L; TRIP6; SFPQ; ARID4B; ZNF443; SMARCD2; NFAT5; NCOA6; ZNF266; NR1D2; BCL11B; TMF1; BLM; SMARCE1; RCOR1; BBX; SIAH2; TLE1; MED13; SAP18; ASH2L; ATF1; ZNF432; STAT6; ZZZ3; YWHAB; BIRC2; BCL10; ZFP64; ATF7IP; DNAJC1; RELB; ZFHX4; BAZ1A; MED23; CDK8; GATA2; DNAJC2; SERTAD2; SMAD6; TSC22D2; ZNF146; KDM5A; MYB; PIAS2; STAT3; BRD3; NFKB1; PREB; JARID2; SPEN; TAF1D; NKX3-1; CUX1; ZNF217; FOXJ3; BRF2; NCOA1; VEZF1; SFMBT1; DRAP1; MYC; CRY1; SMAD7; NR1I2; OLIG2; ZNF189; RNF141; EMX2; TRRAP; KLF10; ZNF302; KLF6; PITX1; RFX5; ZFP36L2; TP53; FOSL1; KDM5D; SCAND1; NRIP1; PIR; TOB1; DMTF1; KAT6B; TBL1X; MYCN; ZBTB18; STAT1; FOSL2; FOXO4; SMAD3