Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID79335	Pyrvinium	GSE92742	FIBRNPC	Human	24h	10uM	EID0471

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	SUZ12; EED; BHLHE40; CRY1; KLF4; NR3C1; NFKBIA; TOPORS; FOSL1; CEBPA; ARNTL; ZNF24; CREBZF; HCFC2; DAXX; ZNF131; RYBP; TLE1; MED13; MEIS1; HMGA2; ZEB2; ZNF200; NFIL3; AFF1; ERF; HLX; NFKBIB; BAZ1B; PHF1; RCOR3; COPS2; ETV5; ETS2; BRD2; MECOM; NPAT; JAK2; CIR1; RBPJ; ZNF432; EMX2; BCL10; HIPK3; MED17; LITAF; TOB1; RSF1; ZNF267; NLK; EGR2; NRBF2; MXD1; BBX; SOHLH2; TSC22D4; ZBTB7A; MAFG; NKX3-1; AHR; SMAD5; TFEB; TP63; TMF1; BRPF1; NR1H2; HTATIP2; CREM; CBX7; REPIN1; KLF9; MITF; NFX1; HOXA5; TBP; BMI1; CREB3; IRF8; ZBTB43; IKZF5; BATF3; JARID2; BATF; HDAC9; DACH1; CHD1; NPAS2; TGFB1; SSX1; CD3D; KDM5A; STAT3; PURA; SAP18; DDIT3; ZNF189; BAZ2B; CBX6; ARID4A; SATB1; MDM2; PIAS2; TAF1D; DPF2; MED1; RNF14; TSC22D2; MAF; SMAD7; MEF2A; JUND; NRIP1; MYRF; FOXF1; CTR9; SATB2; TOX; NFATC3; TBX2; NAB1; DMTF1; ZMYM2; NR1D2; TRIP6; TCF4; ZNF331; SNAI2; ING3; ZBTB38; ZMIZ1; BHLHE41; IFI16; ATF3; ABL1; GATA6; SCAND1
Down-regulation	85	CENPF; RUVBL1; HMGB2; LOXL2; VGLL4; ZNF544; SCMH1; CCNA2; ETS1; PTTG1; FOXM1; ERBB2; STAT1; MYC; EN1; STAT6; DEK; MYBL1; TGIF2; RAN; MNAT1; C1QBP; WDR77; SMARCB1; ILF2; DNMT1; E2F5; POU2AF1; AEBP1; RBFOX2; XRCC6; SHOX2; CDK2; RAD21; NEDD8; ZNF33B; CCNC; TRIB3; ZHX2; CEBPD; TCF12; UBE2L3; SUB1; BACH2; SREBF2; CTNNB1; PRKDC; PSMC3; TGFB1I1; MYCBP; MAGED1; YEATS2; FOXF2; ESR1; ENO1; RBBP7; HIRA; NR2F1; MYBL2; HMGB3; EYA1; ZNF239; E2F8; CALR; PAX5; FOXG1; NFYC; WWTR1; TCF7L1; TCF7L2; ID4; MEIS2; HEY1; ZFPM2; JUP; SF1; MED15; OSR2; RBPMS; CITED2; MYCL; MED12; ID3; SMAD1; KAT6B