Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID79331	Plumbagin	GSE92742	FIBRNPC	Human	24h	10uM	EID0471

Response Information :

Types	Number	Response transcription factors
Up-regulation	245	FOS; ZNF415; TERF1; SALL2; WWP1; LIN28A; ZNF141; TCF21; PRDM14; ZNF117; NANOG; ZNF331; ZIC3; TDP2; ZNF682; ZNF250; PEG3; ZNF345; ZNF34; IRF1; ATF3; ZNF623; ZNF43; ZNF350; ENY2; HLX; ZNF195; ZNF93; CERS4; ZNF544; ZBTB3; HDAC9; ZNF394; TAF11; ID3; PNRC1; GLI2; SPDEF; CDIP1; HESX1; NR4A2; ZNF665; FOXF2; TOX4; ZNF232; ZNF573; FEZF2; SUMO1; NR4A1; ZNF571; SOX2; SOX17; FOSB; TFAP2A; RAD21; BARX1; PEX14; JUNB; SKIL; ZSCAN9; PAWR; ERBB4; COPS5; ZNF675; RING1; ZSCAN31; ILF2; ZFPM2; L3MBTL1; ZNF304; ZNF85; TBX1; NCOA2; VDR; SOX13; TOX; NR1H2; ZNF140; HBP1; PIAS4; ZFP69B; E4F1; DACH1; HEY1; ARID3B; CUX2; AEBP1; BNC1; CBFA2T2; ZNF423; EGR3; HOXB5; KLF10; NR4A3; IRF6; SOX18; CTCF; ZNF257; DLX2; ZNF667; IKZF1; PBX3; SOX3; ZNF74; SOHLH2; INSM1; EHF; FOXA1; TGS1; HOXB13; EGR2; GBX2; DDIT3; E2F3; CSDC2; SUPT5H; ZNF3; ZNF589; ZHX2; NR2F1; ZNF273; RORA; RB1; TCEA1; TWIST1; ZNF91; FOXH1; ZNF235; HES1; CREB1; FOXF1; TGIF1; EGR1; NR2F6; E2F5; MAFF; YEATS4; ZNF10; BHLHE41; ID4; CBFA2T3; TRIM24; ZNF611; DAXX; HOXD1; BNC2; BCL11A; LEF1; KLF3; FOXG1; ZNF107; HOXB2; ZNF136; CBX4; SUPT3H; LHX2; TCF7; PRDM1; TBPL1; ID1; ZNF329; CDK2; XRCC6; ST18; PCGF3; ZNF165; CDC5L; CREBL2; PHF1; NR2C1; ZNF239; ZNF217; MED14; ING4; POU2AF1; RYBP; PAX6; ETS2; BANP; PBX2; CCNH; ZNF83; MYRF; NFE2; ZFP36L2; ZNF354A; MXI1; TAF9; MNDA; ZNF557; NFE2L3; ZBED2; ZNF711; NFKBIB; GMNN; MEOX2; BACH2; ARID5A; GATA6; ZNF467; FOXE1; HMGB1; MKL2; WT1; ZNF177; ID2; MYBL2; IRF7; SNAI2; JUN; TTF2; CRYM; MED17; CREM; PHIP; PKNOX2; TBX3; TAF9B; VPS72; CTBP2; KDM5C; MEIS2; TRIB3; HOXB6; CD3D; JUP; AR; NR3C2; MYCL; MYCN; INSR; TRPS1; HIRA; ZSCAN18; ASCL1; IRF9; PBX1; TGFB1; TAL1; ARNT2; SMAD1; IFI16; HIC2; DMTF1; TOX3
Down-regulation	228	FOXO3; ERBB2; CENPF; STAT1; USP22; TP53; HOXC6; NR3C1; TRIM28; NUP62; TCERG1; SMARCD2; ZNF672; UBP1; KAT6A; CCNA2; TBL1XR1; SMARCA4; TCF12; TRIM32; MED1; HDAC6; SMARCC1; ZNF629; DDX54; ASXL1; ERCC2; NR2F2; NFE2L1; IKBKAP; NCOA4; CHD9; RBM14; MMS19; ZZZ3; FOSL1; PLAGL2; NCOA6; SIX2; KMT5A; PCBD1; SMARCE1; TBL1X; ZEB2; PCGF2; PSMD9; BCLAF1; REPIN1; FLNA; ELK1; YWHAB; STAT3; HOXA10; FOXJ3; MITF; BRCA1; ELF1; BRPF1; ATF1; NELFB; NRF1; IRX5; PURA; ALX1; KDM2A; RHOA; RNF111; LPIN2; ZNF783; SETD2; AATF; TADA3; ATF7IP; USF2; MGA; CARM1; MYCBP; CENPB; DRAP1; PSPC1; TRIM16; HOXA11; ZBTB38; PHF2; BMI1; SP3; STAT5B; ZBTB18; HOXC10; SMARCA5; KAT7; PAX8; MLX; NCOA3; GABPB1; ZNF282; ZFP64; SMAD2; HTATIP2; CBX3; CLOCK; SLC2A4RG; HMG20A; MED13; HLTF; CTR9; TSC22D2; PATZ1; ZMIZ2; WIZ; RNF4; EDF1; TAF1D; NFX1; SREBF2; RNF141; MED24; RUVBL2; WHSC1; STAT6; SERTAD2; ATF6; TFEC; MXD4; ZNF226; MBD2; GCFC2; ZNF384; LIMD1; MECP2; BTAF1; KDM4A; PHF20; PMS1; PREB; FOXO4; TRAK1; PTRF; USP21; PITX1; NCOR1; ZBTB14; DNAJC1; E2F6; EZH2; NFKB1; PBRM1; NCOR2; URI1; ENO1; RUNX1; ZHX3; BASP1; HSBP1; BLM; TAF10; MAGED1; HIPK3; RBBP4; POLR2A; TGFB1I1; ZNF532; EN2; HOXC4; ZFHX4; TBP; SAP30; ZNF148; ZNF587; ZNF189; BPTF; BRD3; ADNP; HMBOX1; SMAD6; BBX; SNW1; AFF1; MEF2A; NFAT5; SATB1; PRRX2; ZNF516; NR1H3; HSF2; TULP4; LMCD1; SFPQ; NFIB; CDK8; BAZ2B; FOXC1; SREBF1; ARNTL2; SIAH2; NAB1; KDM5D; TCFL5; SPEN; TMF1; MAZ; ABL1; KAT2B; CTNNB1; XBP1; BATF; ARID4A; BHLHE40; SMARCA2; RBPMS; PHOX2B; KDM5A; TRIP6; HOXB7; EMX2; ZBTB16; FOXD1; FOXL2; ZEB1; TLE4; CBFB; SUV39H1; KAT6B; MSX1; JARID2; CRK; SCAND1; TXNIP