Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79324 Oxamflatin GSE92742 FIBRNPC Human 24h 10uM EID0471
Types Number Response transcription factors
Up-regulation 122 PPARG; ADRB2; NPAT; MYC; ZNF45; EED; ARNTL; NFIL3; MTF2; RUVBL1; ECD; RBBP5; NFIB; SMARCD2; MNAT1; SOX10; TBPL1; CEBPA; EGR3; HEY1; BBX; CCNT1; GATAD2A; JUNB; STAT3; ZBTB44; TOB1; FOSB; SNAI1; CTR9; KDM5B; DLX2; PPARD; PBXIP1; NR3C2; ZNF226; SMAD5; SND1; ZMYM2; ORC2; ZNF160; TCF7; NR2E1; TBP; NLK; RUVBL2; PURA; IRF4; ZNF175; RHOA; ZNF394; MAF; MLX; TRIM32; CCNC; LMCD1; HLTF; NCOA1; PLAG1; HABP4; MEOX1; ZNF14; BCL11B; SAP18; DACH1; SMARCD3; ZNF443; ZNF331; HDAC1; ZNF124; PARP1; PAX5; HSBP1; MYCBP; EPAS1; RBBP4; MKL2; JUN; TERF1; HSF2; CREG1; ETV5; PRKDC; ZNF266; TCEB2; KLF9; CREM; TLE1; PIAS2; FOXC1; CRY1; SSX1; ID2; ZBTB18; ID3; ENO1; ASH2L; JARID2; PHF20; CHD7; CRYM; SMAD7; SOX9; SETD3; SATB2; TBX3; SMAD2; MED1; ASCL1; LEF1; ATF3; TSC22D2; ID1; NFAT5; BMI1; PEG3; NR2F2; SMARCA2; TXNIP; TOX3; NR1D2; CRK
Down-regulation 142 ATF5; ERBB2; FOSL1; CCNA2; CENPF; FOXM1; HMGB2; NFATC4; TP53; PMF1; PCBD1; SCMH1; ZBED1; TFEC; TGFB1I1; HOXB7; CTBP1; HDGF; MBD3; DEK; NCOA2; WIZ; ZNF710; NFKBIA; DNMT1; ZZZ3; STAT6; TCEA1; TFDP1; MED16; CBX5; CAPN15; ZNF219; SP140L; WHSC1; IRX4; HOXB6; ZNF787; ESR1; KLF11; HSF1; ZFP36L2; CTCF; CERS4; NFE2L1; CEBPG; ARL2BP; NFIC; TULP3; OVOL2; KAT8; MTDH; ZNF282; BARX1; NFKB1; PLAGL1; E4F1; TEAD4; HOXB2; ZHX2; MYBL2; ZFHX3; AEBP1; GFI1B; ZNF467; DDX17; CENPB; EN1; TRIM22; CEBPD; XBP1; ATN1; ZNF512B; PTTG1; RBM39; REPIN1; SMARCB1; PHF2; ARNTL2; JAK2; NCOR2; TBL1X; GRHL2; MNDA; IRF1; CARM1; PITX1; MAFB; CSDE1; RBPMS; TTF2; IFI16; CHD9; HOXD3; MEIS1; TCF3; EMX2; NCOR1; ZNF580; ARNT2; RREB1; ZNF33B; TRIB3; TRIM29; CIZ1; NKX2-2; ZSCAN31; PRRX2; PRRX1; ZFP36L1; ST18; PHIP; YBX3; ELF4; BAZ1A; TFAP2C; TCF7L1; SIAH2; HMGB1; HLF; PATZ1; MYBL1; AR; SMAD1; INSR; FOXA1; TFAP2A; SOX17; ARID1A; CTBP2; ARID5B; NFE2; KAT6B; MEIS2; TRIP6; GTF3A; VGLL4; TRPS1; NRIP1; OSR2; SUV39H1; WT1