Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID79166	Hydroxychloroquine	GSE92742	FIBRNPC	Human	24h	10uM	EID0470

Response Information :

Types	Number	Response transcription factors
Up-regulation	104	SPDEF; FOS; E4F1; ABT1; POLR3C; ZNF74; ZNF91; PIAS4; DAXX; ZNF85; PHIP; COPS5; TFAP2A; HOXB5; ZIC3; ELF5; IFI16; CBFA2T3; HOXD1; ZNF43; MYBL2; SOX13; ZNF165; MEIS2; PSMC3; TFAP2C; ZNF354A; HBP1; NR4A3; SPEN; PQBP1; MED17; ZEB1; CDIP1; EPAS1; ZNF273; MYBL1; CTBP2; ARNT2; SALL2; IRF9; ST18; VPS72; APEX1; ZFPM2; BNC2; ZNF232; PEX14; AIP; NANOG; ZFX; IRF6; BCL11A; RBFOX2; SMAD1; EMX2; NKX2-1; ZNF117; NFE2L3; ZNF552; TTF2; LIN28A; CUX2; SOX11; FOXI1; WNT4; WT1; FOXF2; NR3C1; ISL1; ACTL6A; RBPJ; TULP3; SOX17; ZFP36L2; HOXB2; ZHX2; GRHL2; WWC1; JUP; HMGN3; TRIB3; TP63; RBPMS; ZNF611; CD3D; ZNF423; HOXB6; BHLHE41; CERS4; FOXE1; OSR2; TOX; ELF3; BACH2; GATA6; YBX3; PBX1; MEOX2; ZNF652; CDK2; HHEX; FOXF1; ERBB4
Down-regulation	125	PCGF2; ZFP36L1; ZEB2; NFAT5; HLTF; MSC; PURA; MED1; CARM1; BBX; PPARGC1A; MNAT1; BHLHE40; NUP62; KDM5D; SF1; PDLIM1; BAZ1B; MAFB; STAT5B; USF2; SFPQ; HDAC4; ID2; TSC22D2; CHD1; ZNF148; SMAD2; SIAH2; SMARCE1; TAF10; MLXIPL; LMCD1; REST; TRIM32; ZBTB7A; NCOA1; CCNA2; ZBTB43; TSC22D4; NCOA4; KDM2A; ZMIZ2; FOSL2; HOXC6; NR1D2; JUNB; MED4; PHF1; HOXC4; FLNA; BMI1; HCFC2; E2F3; CREB3L1; UBP1; LEF1; ELF1; FOXD1; POLR2A; REPIN1; FOSB; MAGED1; MLX; AATF; SATB2; ZBTB38; KAT7; TP53; NEUROD1; PIAS2; ZMYND8; SKI; HOXC10; STAT3; NRIP1; BRD2; DNAJC1; RBM14; HTATIP2; BATF; NR2F2; KLF5; NFIL3; ING2; TBX3; ZBTB20; CREB3L2; KLF10; NR1I2; BCL3; IRX5; MSX1; VEZF1; MAZ; MBD2; SMAD7; KAT6A; TSC22D3; YWHAB; KLF13; BIRC2; TOB1; KLF9; FOXC1; SATB1; JARID2; ID1; MYCBP; SMARCA2; ZMYM2; KLF2; PIR; SMAD6; BTG1; NAB1; NFKBIB; ID3; MAF; TSC22D1; XBP1; CITED2; RELB; IKZF1; E2F2