Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79074 Pyrvinium GSE92742 FIBRNPC Human 24h 10uM EID0469
Types Number Response transcription factors
Up-regulation 192 BHLHE40; SUZ12; FOSL1; HMGA2; RSF1; ZNF84; KDM5A; SNAI2; EGR2; HCFC2; BTAF1; EED; NFKBIA; TBX2; NFIL3; TBX3; AFF4; ZNF274; NPAS2; ZNF202; IRF8; TLE1; MED17; GATA6; TFEB; MEOX1; TRIM33; ZNF24; SOX10; RCOR3; BAZ1B; TOPORS; PRDM4; ZNF473; KLF4; MDM2; CDC5L; ZNF131; CREB5; ZSCAN9; ZNF562; HLX; FUBP1; COPS2; ZNF432; HOXA5; SOX4; CREBZF; ZNF146; ZMIZ1; RBPJ; ZNF174; FOXF1; DDIT3; TRPS1; ZNF211; NR3C1; HEY1; TCERG1; GON4L; ZNF143; TMF1; TAF9; MED4; CRY1; MEF2A; HES1; ATF2; ZSCAN32; PAXBP1; ZNF222; LITAF; ZNF337; NRBF2; ZNF324; NR1H2; RBBP8; JUND; TFAM; BCL10; ZNF415; SIN3B; WWTR1; HDAC9; ZBTB7A; BHLHE41; TRIM29; TDRD3; YAP1; TWIST1; ZNF611; FOXK2; ETV5; ZKSCAN5; TOB1; TCF21; VGLL4; SMAD7; ZBTB1; MECP2; PPARD; RORA; INSR; IRF4; SMAD3; MEIS1; ZNF195; SATB2; HOXD1; ZNF302; ZNF614; ZNF654; MAF; CREM; SMAD5; ZNF426; ZNF43; HIPK1; ATF3; MED21; MYRF; ZNF557; EGR3; TAF7; HMBOX1; PBX3; SERTAD2; NR2C1; HBP1; ZNF14; ZFP36L2; ZNF189; ZNF200; ABL1; ADNP2; ZNF264; BBX; NFATC3; CBX7; ZNF468; ZNF331; ZNF83; NKX3-1; ZNF304; ZNF267; IFI16; PEG3; ZNF419; HOXD3; ARNTL; AHR; CBX6; BMI1; DMTF1; CBFA2T2; DPF2; ZNF91; NFIB; MECOM; ZNF354A; BAZ2B; JUNB; ZNF136; BNC2; KLF5; ST18; ISL1; CHD1; ZNF165; EHF; BTG1; ZNF134; PIAS1; SOX9; MAFG; ZNF266; HOXA10; FOSB; RARA; SSX1; PHIP; ZNF329; KLF9; ZSCAN18; TP63; MED1; MITF; ZNF232; ZNF586; ZEB2; KLF10; ZIC1
Down-regulation 65 CCNA2; ERBB2; RUVBL1; PTTG1; HMGB3; LOXL2; MNAT1; CENPF; SMARCD2; FOXM1; PSMD9; TGFB1I1; HMGB2; CHAF1B; NFYC; CEBPD; ZNF580; MYC; NR2F1; SMARCB1; EZH2; TRIB3; MED12; MYCL; ZNF32; HDAC6; TCF7L2; TEAD4; MAGED1; PMF1; ERCC2; CCNC; ITGB3BP; NEDD8; MAZ; ENO1; CITED2; MYBL2; TCF25; RNF141; MYCBP; RBBP7; PDLIM1; CALR; HNRNPD; SFPQ; SUB1; NPM1; STAT1; RREB1; STAT6; MYBL1; PAX5; HOXC10; TOX; MYT1L; SREBF2; DEK; CARHSP1; NR2F2; AIP; PIR; AEBP1; IRX5; SUV39H1