Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79064 Oxamflatin GSE92742 FIBRNPC Human 24h 10uM EID0469
Types Number Response transcription factors
Up-regulation 117 RELB; ECD; TAF4B; TBPL1; PKNOX2; CCNC; SPIB; ZNF235; ZNF671; MTF2; SETD3; RHOA; ATF6; MXI1; ADRB2; PBXIP1; ZNF576; CCNE1; HINFP; ZNF224; ZNF223; SOX10; HIVEP2; CHD7; ZNF222; MKL1; MEOX1; SNAI1; ZNF253; ZNF667; HDAC2; CBL; ZNF665; ZNF45; POU2F2; FOXG1; TGIF2; CTR9; MNAT1; ZNF8; PRKDC; ZBTB25; ZBED2; MYT1; ERF; JUNB; RUVBL1; KDM5B; HDAC3; CREB5; ZNF654; ZNF133; THRA; RUVBL2; ZNF544; BCL3; NR2E1; MKL2; PAX5; ZNF211; ILF2; ZNF415; PARP1; BCL11B; SIRT2; JUN; E2F5; MYC; ZNF552; ZNF227; SALL2; ZNF124; ZNF419; BACH2; ENO1; FOXO1; HMBOX1; GTF2A2; IRF4; TBX3; ZNF195; NFATC3; ZMYM2; C1QBP; ZSCAN18; SOX9; ZNF281; SATB2; ZNF606; TGFB1; RFXANK; ID3; ZNF239; ZNF331; NFIL3; TCF7; BBX; HHEX; DLX2; CUX2; MYCBP; ZNF551; NR0B1; PURA; MYRF; YEATS2; MYCN; LEF1; TCF4; NFKBIB; ZNF586; ZNF232; NKX2-1; SOX11; CREB3L2; PEG3; HMG20B
Down-regulation 160 FOSL1; ERBB2; FOXM1; CCNA2; TP53; TGFB1I1; XBP1; TFCP2L1; HMGB2; NCOA2; PCBD1; CENPF; CEBPG; BRD8; TEAD4; CBX5; BCOR; RBPMS; TRIM22; RBM14; RNF138; TULP3; ELF4; KAT8; HMGB3; ING2; FOXF2; SNAI2; NFATC4; ZFX; DNAJC2; WWP1; NUP62; RREB1; YEATS4; SAP30; KAT6B; YBX3; WHSC1; PRRX2; BRCA1; STAT6; PLAGL1; HOXB7; REPIN1; SMAD4; ARL2BP; PTTG1; CHAF1B; HDAC6; DEK; ZZZ3; USP22; PATZ1; TFDP1; MYBL2; BASP1; PHF2; SMARCA4; CARHSP1; CENPB; BHLHE40; TRIP6; EN1; NCOR1; NCOR2; HDGF; TRAK1; KLF4; NFE2L1; KMT2B; BCLAF1; CIZ1; RRN3; HLF; CTBP1; NFYB; SCMH1; ZNF580; INSR; NFKBIA; TBL1X; ESR1; CAPN15; HSF1; FOXA1; SOX17; TGIF1; PMF1; SLC2A4RG; HOXB2; TRIM29; SMARCB1; CBX3; ETS2; ATF1; SFPQ; KAT2B; NCOA4; UBP1; BRD2; ZBTB16; PRMT2; SMAD3; SP140L; ZNF516; RNF6; ELF3; CTNNB1; CREB3L1; HOXA10; FOXD1; ZNF146; EYA2; IRX5; SPEN; REST; TRPS1; TSC22D3; AHR; BRD3; LPIN2; BTG1; KAT7; CTBP2; POLR2A; TFEC; MEIS1; HIPK3; ZFPM2; KLF11; PRRX1; KLF2; HOXB6; MEIS2; ATF5; BAZ2B; TFAP2C; ZBED1; MAZ; SIAH2; ZIC1; HTATIP2; NR1D2; KLF10; IFI16; ZEB2; FOSL2; VGLL4; ARNTL2; OSR2; HOXC6; NRIP1; CITED2; HIC2; SUV39H1; SMARCA2; MAFB; AEBP1; ZBTB20