Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID79037 Hydroxychloroquine GSE92742 FIBRNPC Human 24h 10uM EID0469
Types Number Response transcription factors
Up-regulation 52 NFATC3; KAT6B; EYA1; NFAT5; ARID5B; ZNF423; MECP2; ZNF669; GTF2IRD1; ZNF32; E2F3; LPIN2; RAN; SIX1; TERF2; ZFHX4; MDM2; TWIST1; KLF2; NR2F2; NPM1; REPIN1; CTR9; LEF1; PCGF2; PTTG1; MED6; SALL1; PHF20; ZNF217; ERBB4; ZIC1; SSX1; PURA; SATB2; KLF9; MEIS2; NR3C2; TXNIP; ZEB2; SMAD6; ID3; NRIP1; MAF; MAFB; NFIB; ZKSCAN1; CRY1; YWHAB; MAGED1; KDM5D; ZBTB18
Down-regulation 51 PBXIP1; IRF6; EMX2; ATN1; INSR; PARP1; IRF8; ACTL6A; CDK2; TERF1; NPAS2; IRF1; PAWR; ETS2; TRIB3; ZFP36L2; SMAD1; NR1H3; BASP1; NFKBIA; DNMT3B; BHLHE41; ARID1A; RUNX3; IFI16; ZNF544; ZNF165; ZBTB38; MYRF; EN1; ZSCAN18; PAX5; CRYM; HOXD1; BCL11A; WT1; TOX; FOSB; TFEC; OSR2; SUB1; FOXL2; BCLAF1; ZNF264; ZNF551; PHIP; TFAP2C; KLF10; ZNF586; ZBTB20; SOX9