Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78812 Aminobenztropine GSE92742 NPC Human 6h 10uM EID0467
Types Number Response transcription factors
Up-regulation 63 PPARG; HOXA5; VPS72; ZNF85; TCEA1; BARX1; POLR3C; CREBL2; CDK2; CCNH; TDP2; BNC1; FOXF2; ZNF331; NR1H2; CDIP1; ATF3; ST18; RUNX1; SOX13; MED15; ZNF232; SPDEF; IRF9; PEG3; DDIT3; PFDN5; MEIS2; SPIB; AEBP1; BNC2; IFI16; ELF4; IRF6; FOSB; PRDM2; PBXIP1; TRIB3; NFATC4; JUN; AES; TGFB1I1; KLF9; TRIM29; TFAP2C; CBFA2T3; ERBB4; ZNF415; FOXA1; MYBL1; TULP3; ZNF91; SNAI2; RBPMS; MEOX2; FOXG1; NPM1; LOXL2; ARID5B; ZFPM2; TBX3; GTF3A; WT1
Down-regulation 83 CARM1; NCOA4; RNF10; VEZF1; ZBTB18; BASP1; REPIN1; HSF2; RFX5; BMI1; HOXC6; HDAC1; HDAC4; SP3; BAZ1B; JARID2; RARA; SALL1; CHD1; YWHAB; ZEB1; ZNF146; CTR9; MSX1; ZKSCAN1; TRIM28; ZNF23; MTA1; CRY1; ZNF302; BRD3; MED1; RFX7; ZBTB11; RBM14; FHL2; HAND1; ZKSCAN7; SMARCC2; MAGED1; TBL1X; CREB5; TSC22D2; ETS2; ZNF184; TRRAP; HEY2; MYCN; ZEB2; PCGF2; RCOR1; HLTF; SF1; ENO1; PHF8; BATF3; ZNF217; EDF1; BAZ1A; BRD8; CHD7; TOB1; HSBP1; ARID4B; SMAD6; ZBTB38; PRKDC; NR2F2; TRIP6; CITED2; MAFB; POLR2A; IRX5; SIX1; SIAH2; MYB; ZBTB20; ZNF281; ASCL1; NR1D2; PBX1; TOX3; SUV39H1