Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID78786	Tolcapone	GSE92742	NPC	Human	6h	10uM	EID0466

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	BMI1; ZNF443; MYB; TERF2; SMAD7; ZNF268; CCDC59; MSX1; ZNF302; VDR; TFEB; ABL1; TWIST1; BCL11A; LEF1; ZMIZ2; ZNF423; SPIB; ZBTB18; SLC2A4RG; EMX2; IRX5; PAX5; ING2; CEBPG; SIAH2; RUNX3; ZNF672; ZNF281; PBX1; MED6; PMS1; TGFB1; RORA; MTF2; CBFB; YBX1; RNF4; MYBL1; NEDD8; CUX2; ESR1; ZNF331; CARM1; BCLAF1; BASP1; ESRRG; CRYM; ZNF32; NKX2-1; PRRX1; ZNF131; AR; TCEA1; SAP30; FOXJ3; SMARCA1; BBX; ZNF432; EYA1; CEBPA; HMGA2; CBX5; TAF7; BHLHE41; SALL1; PFDN5; MAGED1; DACH1; POU4F1; KAT6B; MBD2; RUVBL2; DNMT3B; CREB3L1; RBBP7; INSR; EDF1; ZEB1; NKX3-1; NFKBIB; CEBPB; TOX3; ERBB2; ID3; NRIP1; NFKB2; PSIP1; NR2F6; RUVBL1
Down-regulation	55	GRHL2; ZNF224; E2F3; REST; ZNF264; SRCAP; HINFP; RAN; ZNF652; GATA6; FUBP1; DEAF1; SOX10; MEOX2; BCL3; MEOX1; ZNF217; ZNF7; GLI2; HOXD11; HTATIP2; TAL1; ATF3; MEF2D; RAD21; KLF6; TBL1XR1; HHEX; ST18; AHR; MAFB; HOXB5; CDK8; HOXB2; HSF1; CITED1; CDC5L; CSDE1; RSF1; CCNH; NCOA2; CREB3L2; ETS2; AFF1; WT1; MED13; ZMYM2; NFAT5; CD3D; MYC; FOXO1; ZFPM2; EGR2; EGR1; PAX8