Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78714 Sk-383933 GSE92742 NPC Human 6h 10uM EID0466
Types Number Response transcription factors
Up-regulation 87 NFATC4; CREM; FOS; HMGA1; STAT5B; FOSL1; NR1H4; EMX2; WWP1; CHD4; BNC2; TEAD3; ELF3; SPDEF; PBXIP1; STAT6; ZNF654; SMAD7; CRYM; JUN; ZNF331; NR4A3; HLF; TERF2; CAMTA2; PRRX1; NR2E1; RORA; POU4F1; PLAGL1; TWIST1; ESRRG; ENY2; HMGA2; ZNF22; KLF7; MED14; ZNF165; SMARCA1; TGFB1I1; GATA6; ELK3; CCNC; CALR; ZNF623; SNAI2; ARID5B; MECOM; MED21; ISL1; ZNF544; SMARCD2; ERBB4; SOX17; ABL1; MEN1; ERG; LZTS1; MBD2; CBFB; PFDN5; MYB; MEIS2; TRIM28; IRF7; IRF6; KLF10; FOXG1; TLE4; NKX2-1; TRIP6; FOSL2; CREB3L1; CUX1; IFI16; ZHX2; NKX3-1; AHR; MED13; BCL6; TRIM22; INSR; TOX; TRIB3; TBPL1; FOXO1; RUVBL1
Down-regulation 157 BMI1; CRK; HNRNPD; ATF1; THAP3; DEAF1; CDYL; BRD8; E2F3; SIRT2; ZBTB7A; RBM14; RBPJ; BCOR; ZBED4; HMGXB4; CITED1; RXRA; WHSC1; NUP62; MAFG; ZNF337; ZNF143; GTF3A; MYOD1; CHD3; SIX2; NFKB1; MED16; GATAD2A; FOXO3; HIPK1; BRCA1; HOXB13; TAF4; CTBP1; YEATS2; ATF2; PBRM1; NAB2; TOX3; SIX1; SFPQ; AFF1; ZNF84; SMAD5; CTCF; C1D; MSC; PEG3; ZNF189; HOXC10; MEOX1; ZKSCAN1; THAP11; HOXA11; MAML1; NCOR2; NFIB; NFYC; TFDP2; ZBED1; MAFB; CSDE1; ZZZ3; ZNF14; XRCC6; CDK8; MGA; ZMYM2; PCGF3; BRD3; ARID4B; CBX6; ZNF148; TGIF2; NCOA6; PCGF2; BATF3; PAXBP1; TSC22D1; PAX6; ERBB2; SMARCE1; HMBOX1; MSX1; FUBP1; HMG20B; LITAF; NKX2-2; PHF20; ZFP36L1; TRIM16; MYCN; GLI2; FOXF2; HTATIP2; GTF2IRD1; NFE2L1; SMARCD3; MED6; CTNNB1; KAT6B; ZNF7; SAP30; VGLL4; CENPF; ASCL1; TLE2; MYC; OLIG2; HOXB6; RLF; TAL1; HEY1; FOXJ3; BCL10; RCOR1; BANP; BLM; NEUROD1; CBX3; CHD7; PTTG1; NFATC3; NFKBIB; NAB1; ZNF217; MXI1; ENO1; CBFA2T2; ZBTB11; SOX10; DDIT3; PHF8; ELF4; ZNF124; TRIM29; FOXF1; ETS2; HMGB2; NR2F2; MED1; HOXB7; KLF11; PBX3; NR2F1; NFKB2; EGR2; ZNF652; HOXB2; BASP1; PIR; XBP1; CEBPA; EGR1; FOXO4