Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78518 Mk-801 GSE92742 NPC Human 24h 10uM EID0464
Types Number Response transcription factors
Up-regulation 99 NFATC3; MYBL1; ZNF117; PPP1R13L; ST18; PRDM2; ZNF512B; TFEC; TLE2; TCEA1; ERBB4; ZHX2; ZFP69B; TGFB1; RAD21; TRIB3; NR1H4; ZNF532; ZNF354A; ZNF350; AHR; SCAI; BACH1; ZNF623; ZNF91; ZZZ3; FLI1; EN1; NFE2L2; TFAP2C; FOXE1; TBX3; TAL1; ZBED2; HLF; SSX1; TERF1; NRIP1; CBX7; OVOL2; NFKBIB; NKX2-1; HOXD1; BCL6; TTF2; TRPS1; PEG3; NR1D2; COPS5; FOXN3; TFAP2A; JUP; BHLHE41; NR4A2; JUN; ATF2; ATF4; SOX17; RSF1; ZSCAN31; HDAC9; HOXD3; DDIT3; SNAI2; BPTF; IRF8; ZNF165; PTRF; E2F8; REL; UBE2B; CEBPB; HBP1; MNDA; CREBL2; TRIM22; DNAJC2; ZFPM2; TRIM29; HOXB2; IFI16; FOSL2; KLF11; NKX3-1; PSPC1; CREB1; SMAD7; HOXC10; DMTF1; MXI1; TOX; XBP1; PHIP; CTBP2; IRF6; BASP1; ZMYM2; PUF60; CRK
Down-regulation 96 TBP; SCAND1; GLI2; E2F2; MTA2; HEY1; PARP1; TFDP1; PCGF2; BLM; ZNF516; THRAP3; ING3; MYCBP; KDM5A; CCNA2; STAT5B; HMGB3; RUVBL1; POLR2A; NCOA1; SUV39H1; CALR; TP53; ENO1; BMI1; KDM5B; ZMIZ2; BATF; MED1; PSMC3IP; CHAF1B; MSX1; ZBTB24; TSC22D4; GATA4; TBPL1; MYBL2; FOXD1; CREG1; RHOA; BRD3; EDF1; HSF2; NFATC1; KDM2A; CHD8; NFKBIA; SP110; COPS2; GABPB1; FOXO3; NELFB; MYRF; MAX; FHL2; STAT5A; DNAJC1; ELK1; TFDP2; BATF3; ATF6; TGIF2; NAB1; EYA2; ALX1; DNMT3B; ZNF211; RUVBL2; DLX2; PDLIM1; MYCN; ABL1; NR2F2; FLNA; JARID2; BRCA1; TCF21; HLTF; TAF10; ZBTB18; PAX6; RBBP4; ZFHX4; ZBTB1; CRY1; ETS2; ZFP36L2; RBBP7; UBE2I; BNC2; TOB1; MEIS1; SMAD3; HOXC6; ID1