Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78516 (+/-)-7-hydroxy-2-(n,n-di-n-propylamino)tetralin GSE92742 NPC Human 24h 10uM EID0464
Types Number Response transcription factors
Up-regulation 81 CCNH; SPDEF; HOXD13; NFATC4; CEBPB; ZNF215; TCEA1; NR1H4; ARL2BP; CNBP; TRPS1; IRF6; SOX17; PROP1; BNC2; PRDM14; HIC2; SATB2; KLF4; IFI16; NR4A3; TP63; SOX13; NR1H2; GMNN; ING4; XRCC6; ZIC1; ZNF331; MYCL; BTG1; ZFP36L2; ATF3; PBXIP1; CBX7; HLF; LHX6; NR5A2; HBP1; CREBL2; MECOM; SMARCA2; ARID5B; POU5F1B; PBX1; MAFB; PNRC1; KLF11; OVOL2; HIPK2; PBX3; JUN; ACTL6A; MED21; JUP; FOXG1; MYBL1; BCL6; SNAI2; ZNF711; PFDN5; ZBTB16; ELF3; TFAP2C; EYA2; PAX6; ZXDC; TRIB3; BHLHE41; ARNTL2; PRRX1; NANOG; GATA6; KLF6; LIN28A; CTBP2; NR4A2; MXI1; ID4; CDK2; PUF60
Down-regulation 148 ATF5; PCGF2; CITED1; PSMD9; KDM5A; HMGA2; ZFP64; BRD8; TAF4; ZNF45; ZNF23; TRRAP; TGFB1I1; FHL2; TFDP1; CCNA2; ZNF146; TCF12; RFX7; TFEB; SETD3; KDM5B; NEDD8; SMAD6; TRIM24; NCOA6; ERF; MED1; SAP30; BATF3; CTR9; ZKSCAN7; ZSCAN31; UIMC1; WDHD1; CRY1; COPS2; UBP1; SNW1; ZNF292; ELF4; NCOR2; C1D; ADNP; RBM14; MEOX1; NFE2L1; ZNF248; SIX1; NFYC; EP400; NUP62; BAZ1A; KMT2A; SETD2; ZNF587; RNF6; HOXB7; MTDH; CREB3L2; ERBB2; PSMC3IP; SUV39H1; ZNF84; HSF2; SOX4; ETS2; MGA; BAZ1B; RUNX1; BMI1; ORC2; NR1I2; MEF2A; BAZ2B; KAT6A; AFF1; NFAT5; MEN1; MYB; HMG20A; MTF2; RNF10; ID3; MDM4; DNAJC2; CCNE1; PBRM1; CUX1; BCLAF1; MAGED1; PHF8; CCDC59; TSC22D2; HOXC6; FOXJ3; TMF1; HNRNPD; TLE4; ZNF131; ELK1; HOXB6; BBX; ZNF443; DLX2; ARID4B; ASCL1; SMAD2; TBL1X; ZNF184; POU2AF1; PMS1; CHD9; CBFB; RNF111; XBP1; DNAJC1; RBBP8; PATZ1; PHF20; STAT3; TOX3; BCL11B; ZNF12; ZBTB1; E2F3; ZNF217; GTF3A; SERTAD2; BRCA1; RBBP7; HDAC6; NKX3-1; CHD1; ZMYM2; ELK3; MSX1; BASP1; LEF1; CERS6; ZBTB18; PSPC1; FOXD1; ZKSCAN1; TLE1; PEG3; SMAD3; NR3C1