Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78474 Ggti-2133 GSE92742 NPC Human 24h 10uM EID0464
Types Number Response transcription factors
Up-regulation 59 EED; ZNF516; MLLT10; CEBPB; PRKDC; ZNF93; CBFA2T3; ZBTB20; HMGB3; MKL1; INSM1; ENO1; FOXO4; ELF1; NAB2; SOX9; SPDEF; SPIB; MZF1; MNDA; ARID1A; HEY2; SATB2; ZHX2; MAFB; BANP; BCL11A; NEUROD1; KDM5C; BACH2; ZNF500; BTG1; JUN; MED15; EYA2; ENY2; ZFP36L2; ZBTB18; HEY1; PAX5; NR2F2; NKX2-2; PNRC1; PAX6; FLNA; PBX3; HOXB2; TBL1XR1; ID4; JUND; UBE2I; HHEX; MITF; BASP1; FOXG1; CTBP2; ZNF331; HOXC6; PUF60
Down-regulation 74 PSIP1; SUB1; KAT7; TFCP2L1; CNOT2; NR2C1; TGFB1; CD3D; KDM5D; CRY1; TGFB1I1; ING2; ZNF281; BATF3; SAP30; SMAD2; TSG101; DNAJC2; PBX1; PSMC3IP; HMGN3; FHL2; INSR; NFE2L1; ERBB4; NR1I2; HDAC6; ZNF165; PMS1; ZNF652; STAT3; SMAD1; MEOX1; TOB1; ZNF587; ZBTB38; TLE1; ZNF131; CTR9; PPARGC1A; IKBKAP; NUP62; RUNX3; HOXD1; SMAD7; CBFB; EGR2; LMCD1; MECOM; TRIM22; ELF5; TAF10; SIX1; NKX3-1; KLF10; BPTF; NFIB; GTF3A; PHF20; DMTF1; MYC; XBP1; MEIS1; ZBTB1; SMAD3; TOX; PHIP; ZMYM2; NR4A2; IFI16; ZFPM2; PEG3; ASCL1; NR3C1