Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID78439	Tolcapone	GSE92742	NPC	Human	24h	10uM	EID0462

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	TXNIP; GATA3; MYBL1; ZNF768; CCNC; ZNF136; ZNF721; ZNF160; NLK; REL; HIRA; KDM4C; ZNF165; ZNF611; IRX5; PBXIP1; PEG3; ZFP36L2; NR3C1; ZNF133; URI1; LIN28A; KLF11; BTG1; EVX1; IRF1; AES; SHOX; MNDA; BCL11B; ZNF587; RBPJ; ZNF23; PPARD; TCF7; CITED2; ZNF688; ZNF44; TFDP2; CEBPD; ZNF408; CEBPE; DNMT3B; ZNF91; ZNF174; CD3D; KLF2; OVOL1; ZNF117; PRMT2; ASXL1; ZNF10; NFE2; SNAI1; THAP4; VGLL4; HIVEP2; FOXA1; HDAC5; ZSCAN16; CASZ1; CREBZF; ZMYND8; TP53; ELF5; MAX; COPS5; BATF; GATA1; MBD2; JARID2; YBX1; ZNF430; ZNF665; CDIP1; HHEX; HOXD11; HEY2; SAP30; CREB5; DNAJC1; FOXD1; ZNF43; MXI1; NKX2-2; NFKBIB; RLF; TSC22D1; BANP; CITED1; CCNE1; STAT5A; MYB; NFE2L3; ZNF423; KLF6; NCOA1; E2F2; PHIP; KAT6B; SCAND1; ATF3; ZNF394; HMG20B; MYCN; ZNF652; GTF3A; TSC22D2; TOX; ERBB2; DLX2; INSR; TCEB2; ESR1; CTR9
Down-regulation	141	TFDP1; BNC2; AGO2; SF1; ZNF7; TRIP4; SSBP3; ZBTB44; ZFX; HSF1; MTA1; NFIB; HMGB2; TULP3; HLX; TCF12; ARID1A; SMARCD1; ZNF468; MTDH; ZNF16; ZZZ3; TCF21; SMAD9; WWC1; BCL3; PUF60; COPS2; ZNF557; EN1; HCFC2; REST; ZMYND11; STAT6; NR1D2; ZNF580; LIMD1; MED24; ZMIZ2; TRPS1; IL16; MLX; NFYB; ZFPM2; SMARCD3; IRX4; SOX17; CTBP1; ZNF35; PITX2; KLF10; GMNN; ZNF623; PTRF; SMARCA1; CNOT3; TRAK1; ZBTB18; EYA2; EGR3; ATF7IP; SMAD6; ELK4; IRF8; PIAS3; LPIN2; ALX1; ACTL6A; ATF4; PPARGC1A; BCL11A; CENPB; PIR; FOXO1; TRIM28; TEAD1; XRCC6; HMGA1; CALR; THAP10; PRRX1; KAT7; ZNF532; PAWR; KLF13; EGR2; FOXF1; MYRF; ZBTB20; CNOT2; ENY2; RNF111; UBP1; MDM2; ID4; NRIP1; POU2AF1; SKIL; NAB1; BTAF1; NR2C1; ZSCAN31; ELF1; ZFHX4; HEY1; MYNN; MED13; TRIM32; TRIM29; EHF; NPAS2; ID3; HDAC1; SFPQ; TFAP2C; ZNF331; TBL1X; TGFB1I1; TRIM22; RAD21; SUB1; NCOR2; RUNX3; GLI2; ZBTB16; TP63; LOXL2; ARNT2; FOXF2; TBX2; HOXB2; HOXB7; ZFP36L1; XBP1; MAF; SNAI2; BHLHE41; BASP1; NFATC4; SMAD3; RELB