Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID78368	5-hydroxytryptophan	GSE92742	NPC	Human	24h	10uM	EID0462

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	NR1H2; STAT3; IRF7; CDK9; OSR2; ZKSCAN1; TMF1; RYBP; EVX1; CTBP2; CITED2; ZNF329; C1D; HLX; SIRT2; ZNF587; THAP4; STAT1; CHD8; TRIP6; ISL1; TCF25; CXXC1; KLF6; IRX5; ELF1; CDC5L; SP2; USF2; HNRNPD; TCF15; SMAD4; HMGB3; KAT5; NR4A1; NR1I2; BCLAF1; HMGB2; SIAH2; ZNF124; WWTR1; HHEX; ZNF175; BATF; ZNF430; ING3; GATA6; EDF1; RRN3; NKX3-1; SCAND1; FOXL2; ATF5; TSG101; ZNF134; IRF9; RUVBL2; MAF; ETS2; ZSCAN31; FOXJ3; IRF6; PIR; DNMT3B; RNF138; ELK1; YWHAB; TRIM28; PBX3; FOXC1; MYB; PLAGL1; ERBB2; ZNF267; RNF111; SMAD2; ZNF331; AFF1; HTATIP2; TGIF1; ESR1; NR4A2; ZNF91; SERTAD2; FLNA; MAFB; CTR9; NFE2; BASP1; NR2F6; PUF60
Down-regulation	86	SOX2; LEF1; FOXG1; SP140; MYBL1; E2F5; CIITA; NR2E1; DDX17; HEY1; BCL11A; ZNF189; MTA1; POU3F2; CNOT6; ZNF74; ZBTB16; TP63; PRRX1; YBX1; CEBPB; NPM1; GTF3A; RFX5; ZNF107; POU4F1; CALR; TCF3; LHX6; CNBP; ZNF711; THAP11; SOX12; NR0B1; CBX4; SMARCC2; BCL11B; SSX1; ZNF580; PLAGL2; GMNN; ZNF22; TCEA1; TLE1; ZNF195; BACH2; TERF2; TRAK1; ZEB1; MEOX2; ZHX2; ZNF32; ZNF281; NEUROD1; HDAC4; MSX1; LMCD1; ZNF117; PURA; DLX5; TRPS1; SOHLH2; VGLL1; SMARCA1; ATN1; FOSB; POU2AF1; ZFP36L2; MNDA; NANOG; FOXO1; TFEC; USP22; CREBL2; HIC2; SOX9; MECOM; TRIM29; TBX3; HOXC10; MEIS2; HMG20B; TBX2; ID4; E2F2; RELB