Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID78366	Alpha-methylserotonin	GSE92742	NPC	Human	24h	10uM	EID0462

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	GATA3; FOS; TXNIP; LIN28A; ISL1; RXRA; GATA2; BTG1; PBX1; CREB3L2; NFX1; ZNF175; KLF7; PTTG1; HIRA; DDX17; NR2F2; UIMC1; NRF1; HHEX; ZNF211; PHOX2B; DNAJC1; WHSC1; FOXD1; RBFOX2; PPARD; RXRG; ZNF516; ZBTB7A; TBX3; PITX1; SIRT7; JARID2; POU2F2; TBP; CEBPZ; HBP1; TRIM24; CITED1; NFKBIA; RBPMS; ZNF500; BANP; ZNF264; SETD3; NR2F1; CITED2; SAFB2; EDF1; ZNF552; CEBPE; BACH2; IRF4; ESR1; GATA1; BASP1; FOXF1; IRF6; PFDN5; DACH1; TAF12; HOXA1; SPIB; ERG; SALL1; HMGB3; ZNF263; ZFP36L2; VGLL1; MYCN; MAX; CALR; HOXC6; CD3D; MSX1; SOX13; NFE2; EYA1; CARHSP1; TFAP2A; AR; MAFB; MAF; ZBED2; ID1; FLNA; PBX3; GATA6; MXI1; HMG20B; HOXB7; RHOA; NR4A2; SIAH2; ZFP36L1; TBL1X; AFF1; MEIS2; TCEB2; EPAS1; TOB1; SMAD1; NR2F6; MTA1; TRIB3
Down-regulation	152	YEATS4; RELA; ZSCAN18; FOSL2; THAP1; DMTF1; AGO2; EMX2; PRKDC; PLAG1; NCOA2; ZNF7; CRK; PSIP1; NUP62; DEK; POLR3F; ANKRD1; CNBP; EGR3; BBX; PUF60; NFIB; VDR; NR2C2; GCFC2; TTF2; MDM2; NR1D2; FOXJ1; BRCA1; KLF13; MEOX2; PLAGL2; ZNF195; URI1; HSF1; MTDH; USP22; MYBL1; EGR4; RUNX1; HDAC6; PROX1; PEX2; TFCP2L1; E2F5; WT1; ILF2; NFYB; ZNF131; SMAD6; MED7; CEBPG; ACTL6A; FOXN3; COPS5; REST; XBP1; LPIN2; UBE2B; CRY1; ZBED4; POLR3C; RBL1; NR3C2; BATF3; APEX1; SNAI2; SALL2; TAF7; POU4F1; E2F3; BRIP1; ZNF281; NAB1; SAP30; SMARCA2; NFIL3; RBM39; LMCD1; ZFPM2; EED; ATF4; CCNT1; TERF2; GMNN; KLF5; SP3; SFPQ; ZNF623; CREB3; MED6; FOXG1; TCEA1; CBX5; HMG20A; RNF138; ZNF14; TOX; ARID5A; RAD21; HMGB2; PLAGL1; LEF1; TEAD1; ZIC1; HOXD1; ZNF529; E2F8; WWP1; ZNF226; KLF10; NCOR2; YWHAB; ATF2; TOPORS; XRCC6; MEOX1; ZZZ3; CCNE1; HDAC9; SMAD2; ARID5B; SMAD7; BCLAF1; ZNF512B; NRIP1; RNF6; ATF3; TRPS1; ZNF217; SOX17; TFEC; UBP1; RBBP8; TRIM29; SMAD3; ASCL1; TERF1; AHR; MKL2; TBX2; CTNNB1; NPAS2; NKX2-1; EGR2; ETV1; ZBTB38; E2F2; ERBB4; RELB