Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID78364	Mk-801	GSE92742	NPC	Human	24h	10uM	EID0462

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	HES1; BTG1; DDIT3; EZH1; AATF; CITED1; PDLIM1; PBX3; ZNF506; MNDA; GATAD2A; PCGF2; KLF6; ETV4; KDM4C; ZNF587; ZNF562; HINFP; MED1; KLF1; IRF6; FOXD1; NFE2; CITED2; BHLHE41; ZBTB7A; HHEX; AGO2; JAK2; ZNF771; ZNF611; ATF4; TOX3; TRIM27; DACH1; YAP1; HDAC9; ZNF544; TCF21; SIX2; ZNF593; CTBP2; SIX1; SOX13; HOXA11; ZNF160; NFKBIB; GFI1B; HOXB6; RFXANK; RLF; SOX9; TCF7L2; ZHX2; ZNF665; ZNF264; ZNF263; ZNF124; ZNF721; MED13; BRD4; HMGB3; JUP; ENO1; INSR; ZNF117; TFAP2A; SAP30; ERG; ZNF83; EPAS1; PIR; JUN; MYCL; SERTAD2; TRIM29; NR4A2; IRF8; ETV5; HTATIP2; ZBTB20; RERE; MXI1; PEG3; TGIF1; ID4; CEBPD; ZMYM2; WT1; NR2F6; HOXB2; ETV1; ZFPM2; NR2F2; ZNF91; FOXC1; HOXC6; PUF60
Down-regulation	102	PSIP1; HMGN3; NFIB; ZBTB18; BRIP1; PHF20; ZIC1; TRIP6; MED4; ZNF536; MED6; MED21; SETD2; TOPORS; BASP1; EMX2; SREBF1; EGR3; YEATS4; CREBL2; BCL11B; ARNTL2; TRPS1; CREM; FOXN3; ZNF512B; PTTG1; ZNF654; CCNC; DNAJC2; SUMO1; ZNF281; HLTF; REST; ZNF529; ITGB3BP; PATZ1; SPEN; NUP62; NFYB; PLAGL1; WWC1; ATF1; RBPMS; DMTF1; ZNF22; BAZ1B; GMNN; TLE1; MYCBP; TOB1; PFDN5; CNBP; MYT1L; TOX; BCLAF1; BPTF; EED; UBE2B; NEDD8; SP3; ZBTB16; TRIM28; NR1D2; SMARCA1; MTF2; TCEA1; CARHSP1; DEK; CCNE1; RUVBL2; YWHAB; TFDP2; NAB1; ELK3; PHOX2B; NRIP1; ZFHX4; NKX2-1; EZH2; MEOX2; BRD8; HMGB1; NR4A1; UBP1; ID3; JUNB; HLF; SPIB; CD3D; KLF4; MTA1; ZNF226; SHOX2; ZBTB38; FOXF1; CEBPZ; RORA; NFATC4; ETS2; SUV39H1; RELB