Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78198 Aminobenztropine GSE92742 NEU Human 6h 10uM EID0461
Types Number Response transcription factors
Up-regulation 55 BCL11A; MSC; ATF3; FOXD1; CDX2; MED14; JUN; JAK2; TEAD3; KLF6; HOXB7; CDX1; PNRC1; MNDA; PRDM14; CEBPD; HLX; RFXANK; COPS5; HIRA; FOXA2; FOXF2; IRF1; ZNF85; ILF2; IRF6; JUP; KLF4; LHX3; C1QBP; OVOL2; SIAH2; LEF1; TRIM16; TDP2; VDR; GATA6; TBX2; TAL1; HOXA1; SSBP2; TFAP2A; NFE2; SUB1; CDK2; CEBPB; KLF13; STAT1; CBFA2T3; CALR; CREB3L2; SOX9; HDAC9; NANOG; VPS72
Down-regulation 141 TLE1; ZNF532; NUP62; HDAC6; SMARCA1; TSC22D3; CRK; KAT6A; ZNF24; ARID4B; ATF7IP; ZBTB1; MNT; SIX1; CTBP2; BCL10; PHF20; MEOX1; BRD8; MTF2; ZNF419; CHD1; RCOR3; BCOR; SMARCA5; ERBB2; PAX5; SMARCA4; BCLAF1; BAZ1A; SMARCE1; NFIB; HNRNPD; YBX1; RARA; ZMYND8; ZZZ3; PBRM1; MITF; GTF2IRD1; HMGN3; TRIM33; TRAK1; RNF10; CRYM; SNW1; KMT2A; CHD7; SPEN; PAWR; PLAG1; PATZ1; CRY1; DPF2; FOXO1; EZH2; ADNP; TERF2; RERE; PITX1; TCERG1; PBX1; RBM39; MBD2; FOXJ3; MED1; SATB1; RRN3; SETD2; NPAS2; RLF; PSMC3IP; ZBTB18; RUNX3; TP63; BAZ1B; TSG101; NR2F2; SFPQ; BATF; IFI16; ZNF267; CLOCK; SIX2; TCF4; SMAD2; CTR9; BACH2; AFF1; UBE2B; TAF1D; HDAC1; ENY2; NR2C1; TGFB1I1; KAT7; BASP1; RBBP4; ZKSCAN1; CUX2; TRIM28; MKL2; NR4A1; MGA; HSF2; TBL1X; CREM; CNOT2; EDF1; ELK3; ASCL1; BRD3; SMAD1; CBFB; ZNF131; RFX5; BBX; WWTR1; ZHX2; TRIM22; CARHSP1; TULP4; USP22; BIRC2; RBBP8; SALL1; ZKSCAN7; JARID2; FLNA; HMGA1; HLF; ZBTB38; SAP30; OSR2; TGFB1; PBX3; ISL1; AHR; ZMYM2; NFATC3; SUV39H1