Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78099 5-hydroxytryptophan GSE92742 NEU Human 6h 10uM EID0459
Types Number Response transcription factors
Up-regulation 111 ZNF143; SUV39H1; BBX; PCGF2; DNMT3B; DRAP1; NCOR2; KDM5A; ZBTB24; YBX1; SMARCA4; EDF1; RNF4; MSX1; ZNF189; NELFB; CHD7; MYCBP; KDM2A; CRK; ZNF200; TCERG1; HIVEP2; SMARCE1; TRIM28; SMAD2; REPIN1; ING2; TCFL5; PATZ1; NRBF2; TBL1X; DPF2; PIAS2; NFKB1; PQBP1; PHF20; MYCN; TRIM32; MED7; MAGED1; SAFB2; KAT6A; ZFHX4; BRD3; SREBF1; SMARCD3; IRX5; NFATC1; FOXO4; MTF2; ZEB2; SP110; TAF10; PSPC1; BANP; CTR9; SCAND1; MNT; ZNF516; POLR2A; SOX2; RBM14; BMI1; CBX3; TLE1; HTATIP2; BACH2; ZNF443; HNRNPD; DACH1; RBBP4; SMARCA5; NUP62; TBP; ZMYND8; YWHAB; BASP1; FOXO1; CDK8; CBX6; ARID4A; TEAD1; LEF1; EYA1; HDAC6; ENO1; ING3; MED1; KLF2; MEF2A; GATAD2A; FOXO3; HMGN3; MAF; ZMIZ2; MAFG; ELK3; MYB; ZNF281; TSC22D1; BRD4; LPIN2; ERBB2; HMG20B; NR2F1; NFIB; FLNA; ZBTB18; MTA1; SOX9
Down-regulation 65 OVOL2; RBFOX2; HOXC13; NKX2-1; ATF3; MYBL1; NR0B1; PSMC3; JUN; NFE2L2; TBX21; SOX17; ST18; MKL2; JAK2; HOXD1; EPAS1; CDK2; IRF6; E2F8; HOXB6; TAL1; MYCL; NR4A2; AHR; FOXA1; HOXB13; PRDM1; CALR; THAP10; ZNF239; BCL11A; ZNF557; IRF9; FOXL2; IRF8; NR4A1; IRF1; ZNF331; ATF5; POU4F1; KLF10; EN1; JUNB; TWIST1; PHIP; CRYM; ACTL6A; HOXB2; AES; HHEX; LOXL2; ETS1; TFAP2C; FOXF2; MNDA; FOXN3; HDAC9; VPS72; TBX3; ZFPM2; ZNF394; IFI16; ID1; NFATC3