Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78036 Aminobenztropine GSE92742 NEU Human 6h 10uM EID0458
Types Number Response transcription factors
Up-regulation 109 BNC2; HDAC6; BNC1; ZBED2; LZTS1; PLAG1; IRF4; CCNT1; TOB1; ZNF22; IRF1; NLK; RXRA; HES1; GLI2; PARP1; RBPMS; MYCL; CAMTA2; TBX2; GRHL2; KLF6; CHD4; HOXB7; SNAI1; MECOM; PKNOX2; SIX6; EHF; PRPF6; TFAP2A; TEAD1; SSX1; EMX2; NFATC1; ITGB3BP; ATF6; NPAT; RCOR3; ZNF143; SOX17; ZNF354A; CREB1; NKX2-1; TAF10; VPS72; ZNF711; MNT; SPDEF; STAT1; HMGN3; ARNTL; KDM2A; TCF7L2; STAT5A; SSRP1; TULP3; WT1; SMARCA1; MAFF; HOXD1; GATA6; TEAD4; AR; TGIF2; E2F5; SUPT3H; HOXB2; TSG101; NR1H3; FOXA1; STAT4; MKL2; ATF5; CBFA2T3; FOXG1; HOXA1; CEBPD; ZFPM2; HMGB3; CDK2; CDYL; TFAP2C; SOX13; CD3D; BHLHE41; ATF3; NR2F6; IRF9; MYRF; TBL1X; ZNF652; NFE2; TWIST1; CREBL2; RUVBL1; IRF7; TCF7; MEOX2; ELK3; SCAND1; HMBOX1; NKX3-1; ZSCAN18; SNAI2; ABL1; ESR1; HEY1; ZMYM2
Down-regulation 120 CENPB; CASZ1; SP100; CITED2; NR2F1; CTBP1; ZNF669; ZNF189; REPIN1; JUND; MTF2; NEDD8; CNOT3; ELK1; MNDA; ZKSCAN1; ZNF536; EP400; DDX5; ZEB2; SAP30; MED6; GTF2I; ZZZ3; CSDC2; ZNF529; TCERG1; ZIC1; SMARCD3; NCOA4; USF2; UBP1; TCF4; NFKB1; C1D; PRKDC; TGFB1; SMAD4; ZBTB43; ZNF292; SUPT5H; TAF7; HMG20A; FOXM1; NEUROD1; SOX9; ZNF443; DNMT1; PATZ1; CBX3; PAXBP1; HNRNPD; SAFB2; MED1; ZMYND8; MED23; YWHAB; ISL1; YBX1; IKBKAP; ZNF84; RAN; TAF11; IKZF5; JARID2; NR2F2; C1QBP; MGA; FOXN3; NFE2L3; AES; ZNF274; ZNF468; WWC1; ELF1; MED24; NR1D2; DR1; MEIS1; TLE4; BLM; ZBTB18; BRD4; MTDH; TRIM29; NKX2-2; OSR2; BASP1; RB1; TBX3; BCL11A; CALR; TRIM24; TADA3; HIVEP2; PAX5; EYA1; NR1H2; TP63; SOX2; KLF2; ENO1; NFKBIB; URI1; HIRA; NFIB; TBPL1; RUNX1; KAT2B; CEBPA; CITED1; TRIP6; DACH1; ZBTB38; XBP1; NFATC3; FOSB; ASCL1; ETV1; SMARCD2