Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID78007 5-hydroxytryptophan GSE92742 NEU Human 6h 10uM EID0458
Types Number Response transcription factors
Up-regulation 120 CCNT1; EHF; TP63; NFKB2; ZXDC; TFDP2; ETV6; TXNIP; FOXE1; ZIC1; KLF9; NFE2L3; NR3C2; IFNB1; BANP; ZBTB38; PAX8; SOX9; NR4A2; SPDEF; KLF15; TRIM25; LHX3; SOHLH2; MSC; RXRA; STAT2; DDX17; ZKSCAN3; HLF; TCEA1; PRMT2; EZH2; TAF5; ZBTB43; DLX5; ZMIZ2; BHLHE41; ARL2BP; POU4F1; MDM2; SHOX2; BPTF; CNOT2; RUNX1; PBXIP1; DNAJC1; SSX1; ZHX2; MECP2; ZBTB40; PRRX1; HNRNPD; TRIP4; TERF2; SMARCD2; HHEX; CBX7; NFKB1; KLF11; ZNF331; ELK4; TLE2; LMCD1; MED1; CEBPB; IRF6; KDM4C; PURA; CBFA2T3; BBX; CBFB; ZNF589; CREM; JUNB; SNIP1; BAZ1B; TEAD4; ARNTL; SMAD1; KLF4; CERS6; TRPS1; AHR; TAF5L; RBBP7; CCDC59; SNAI2; BCL6; CDK7; SUPT4H1; KLF2; AEBP1; TRIM29; NR1D2; ZFP36L2; FOXN3; MSX1; ING3; ZFPM2; SOX10; FUBP1; RNF138; SP140L; NR0B1; NR2F6; PBX3; OSR2; HLTF; HIRA; HMBOX1; NKX3-1; DDIT3; CRYM; CITED1; TADA3; ATF3; RBPMS; DNMT1; SCAND1
Down-regulation 183 HDAC2; TOX3; TCEB2; TLE4; NEDD8; HOXB6; ZNF711; MNT; LZTS1; RNF141; CARHSP1; HSBP1; ZBED4; HOXB7; ARID3B; TAF1D; NRBF2; NLK; TRIM28; ZNF551; BAZ2B; RORA; RAN; CAMTA1; SMAD6; HDAC5; NUP62; ZNF787; NR2F1; CBX3; MEF2A; PIAS3; ZNF573; MED16; RSF1; ZKSCAN1; GLI3; L3MBTL1; ZNF419; PA2G4; NR1H2; HDAC7; PPRC1; ARRB1; SOX3; MED4; NFATC4; ZNF112; CNOT3; SMARCC2; ALX1; NCOA2; ZNF430; ZNF7; MAZ; FOSL2; SUPT5H; ZNF44; LIN28A; MEF2D; SIX1; ZNF574; SMARCA4; ADNP; E2F5; BRWD1; UBTF; BAZ1A; PSPC1; TFEC; BAZ2A; PBX1; ZNF473; YAP1; ZNF410; IRF3; FOXK2; ZNF813; E2F3; WT1; EHMT2; ZNF22; GATA6; HDAC6; RCOR1; KMT2B; ZNF587; GTF3A; POU2AF1; RB1; PATZ1; RERE; ZNF264; PRKDC; RARA; URI1; HOXC4; PAWR; HDAC4; SMARCA5; C1QBP; TRAK1; DAXX; NHLH2; MECOM; MAGED1; HEY2; EGR3; TULP4; CUX1; CITED2; MYBL1; BCOR; RUVBL2; CREB5; PCGF2; EMX2; ISL1; TBL1XR1; TWIST1; HSF2; ZNF580; HMG20B; MEIS1; ILF2; SP2; POU3F2; BCL11A; SOX2; CBX4; BACH2; VPS72; CARM1; KAT6A; FOXA1; TCF7L1; IKBKAP; DLX2; ARID5B; NFATC3; ZEB1; ZMYM2; FOSB; PLAGL1; FOXO1; ERBB2; DR1; ZNF281; CTR9; HOXB2; CALR; ZNF131; DRAP1; BASP1; ZFHX4; ATF4; ZNF544; ESR1; HMGB3; TSC22D2; PIR; ZNF532; CDK2; STAT6; PITX1; MYRF; RREB1; ZSCAN18; ZSCAN31; PQBP1; TCF7L2; YWHAB; MYCN; PAX5; ERG; ZNF652; TRIM16; LEF1; NFKBIB; CEBPA; XBP1; ID3; ID4