Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77909	Reboxetine	GSE92742	NEU	Human	24h	10uM	EID0457

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	RUVBL1; NR1H2; E2F4; ERBB4; SOX17; ATF5; VPS72; RUNX1; CCNH; SRCAP; RBFOX2; TEAD4; STAT6; TGFB1; TXNIP; ZNF75D; VGLL1; EN1; ZNF444; MED17; NR0B2; PROP1; PRMT2; MYBL2; ATF3; IRF6; ZNF215; CDK7; THAP10; BCL11A; E2F8; ARL2BP; SPDEF; ZNF239; IRF9; HSF1; PSMC3; ATN1; CDK2; HOXC13; MECP2; RBL2; TRIP11; OVOL2; MLXIP; TCF7L2; CNOT3; TAF4B; ZNF235; TRPS1; PGR; HDAC9; EPAS1; NFE2L2; TGFB1I1; SNAI2; IFI16; CBX4; SNAI1; NR0B1; FOXA2; TULP3; NKX2-1; TCFL5; TBX1; JUN; KLF3; NR5A2; SREBF2; SUPT3H; PBXIP1; THRA; TRIM22; GRHL2; POLR3C; ZNF512B; TERF2; MED25; FOXL2; BARX1; TSC22D1; ZNF467; CRYM; FOXJ2; ARID5B; CEBPB; HOXB2; BRD7; CREB3; CBX7; ZNF557; DLX5; ST18; EHF; CUX1; CBX6; MYRF; TAF5L; KAT2A; HOXC10; STAT1; ILF2; KLF10; CBFA2T3; OSR2; ZNF394; TCF7L1; HOXB13; MECOM; FOXM1; TFAP2A; ACTL6A; THAP7; WWTR1; WT1; PAWR; UBE2L3; AEBP1; TFAP2C; MYBL1; CD3D; ESR1; TCF21; TBX21; TCEA1; PRDM1; ELF3; KLF6; ZFPM2; PURA; FOXJ1; KLF13; SOHLH2; PFDN5; FOXF2; PAX5; JUNB; CALR; HOXA5; HIC2; TWIST1; BTG1; VDR; ZFP36L2; KLF5; GATA6; ELF5; JAK2; ETS1; LMCD1; POU2AF1; NR4A1; CREB3L2; HTATIP2; HIRA; JUP; KLF4; ELF4; MXI1; LEF1; FOSB
Down-regulation	202	ZMIZ1; BASP1; MTF2; HMG20B; NRIP1; SCAND1; CITED1; BBX; ZNF23; RBBP5; SMAD2; RBPJ; DR1; DNMT3B; PBRM1; EP400; TCERG1; ZFHX4; JARID2; ZFP64; ING3; MED1; CREB1; PLAGL1; NRBF2; ZNF136; CTR9; SFPQ; BCL10; SAP30; DRAP1; NONO; KDM5A; BRD8; CRK; UBE3A; HSF2; ZMYM2; ZNF84; RNF10; FOXO4; ZNF721; SMARCE1; MYT1L; ZNF614; CCNA2; NCOA6; TLE1; PCGF2; KAT6B; RLF; ENO1; PBX3; MYT1; ARRB1; ZNF292; ING1; TBP; CREB5; PTTG1; TBL1X; ZNF184; KDM4A; BCOR; ZNF189; ZNF302; SNW1; DDX5; ERBB2; RCOR3; MYCBP; EDF1; ZNF529; TLE4; ZNF426; YBX1; C1QBP; MED7; HDAC6; SUV39H1; ZNF268; ZNF160; ZEB2; PRKDC; LPIN2; ZNF672; KAT7; USF2; NFYC; BRPF1; TBL1XR1; EGR3; NFKBIA; PHF8; ADNP; RCOR1; PBX1; GTF2IRD1; PARP1; ZNF587; AFF4; SOX2; ATF2; E2F3; NUP62; TCF7; EBF2; SOX15; EYA1; ZNF177; ZNF468; NEDD8; HLF; TSC22D3; NCOR2; ZBTB1; ZNF593; TMF1; VEZF1; TCF12; PHOX2B; UBE2I; SIX2; RBM14; NHLH2; PIAS2; ZNF93; ZNF44; MAGED1; ZNF562; LZTS1; ZNF611; FLNA; HDAC4; ORC2; ZNF430; EZH2; NFATC4; ASCL1; SMARCA5; PHOX2A; YWHAB; GABPB1; XBP1; MED12; SAFB2; SMAD4; SMARCA4; GATAD2A; PPARGC1A; ZNF148; MED24; ZBTB20; HNRNPD; MAX; MYCN; HMGA1; TAF10; HMGB3; ZNF146; BMI1; HLTF; CARHSP1; CUX2; NANOG; POU3F2; ZBTB38; BAZ1A; CERS6; PRRX2; INSM1; ZFX; MLLT10; BATF; BRD3; KDM2A; NCOA4; ARID4A; MAFB; FUBP1; ZNF131; ZNF432; HIVEP2; ZNF43; ZKSCAN7; TCF4; IRX5; NR1D2; ZNF267; ZNF516; TRIM16; FOXG1; BATF3; TRIM29; BRD2; ZBTB18; PITX1; SATB2; ID3; NFIB; SOX9; HOXC6