Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID77802 Mk-801 GSE92742 NEU Human 24h 10uM EID0455
Types Number Response transcription factors
Up-regulation 96 PAX8; NFKB2; FHL2; NKX2-1; HMGB3; TFCP2L1; POU4F1; MLLT10; EMX2; CREB3L2; TCF4; URI1; MDM4; ZBED2; HIPK3; GTF2I; SMARCA5; MYCL; CNOT1; EPAS1; PBX1; SAP30; MAF; TULP4; NR1D2; TBX2; KDM2A; SMAD1; TCF7L1; USP16; ZNF432; DEAF1; NFKB1; ZNF224; NHLH2; MXD4; BTG1; ZNF165; GTF2IRD1; ING1; TGIF2; DNMT3B; DBP; TRIM24; RBBP4; PHOX2B; ZNF544; ERG; NFATC3; CRYM; TAF9B; LITAF; BHLHE41; ZFHX3; ZBTB38; LOXL2; ESR1; ZNF512B; SIX1; ZNF652; KLF6; PLAGL1; SMARCA1; ZNF551; NPM1; AFF1; ZNF302; NFATC4; WT1; CBFB; JUP; PROX1; ZNF593; WWC1; REL; SALL1; NFKBIB; ZNF587; ABL1; ZNF160; RBBP8; ELF3; MTDH; BASP1; CUX1; IRX5; ELF5; NANOG; YBX1; ZNF423; PAWR; ZNF281; ZNF721; ID3; ASCL1; SCAND1
Down-regulation 76 NCOR1; XRCC6; FOXF2; SIN3B; CBX7; KDM5D; NPAS2; CEBPB; NEUROD1; PCGF1; ZEB2; ACTL6A; ERCC3; HOXB13; HMGXB4; SUPT3H; RCOR1; CDC5L; HDAC9; SNAI2; GATA6; FOXA1; PRDM1; UBE2L3; SOX9; DDIT3; EN2; CBFA2T3; BCL6; MTA1; CDK2; EZH1; GFI1; SIAH2; IRF8; EWSR1; TRIM16; PIAS3; RUNX1; IL16; PIAS1; JAK2; SIRT7; LZTR1; EHF; AR; PLAGL2; NFE2L2; CD3D; ARNTL2; SHOX2; MNDA; HDAC1; NKX2-2; TP63; KLF11; SMARCD3; THAP7; FOXF1; NKX3-1; MYRF; ZIC1; RXRA; BCL3; INSM1; HOXB7; DLX2; OSR2; EGR3; TCF21; MYBL1; NR1H2; AHR; VPS72; HEY1; PPARG