Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77740	Alendronic-acid	GSE92742	NEU	Human	24h	10uM	EID0455

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	RELB; ETV1; NPAS2; ZNF532; MBD1; NFKB1; CDK7; MAF; MAP3K10; IFI16; SMAD9; TUB; CREB3L2; TRIM25; LHX3; TBX5; HOXB13; TFAP2A; AFF4; KLF13; MED20; FLNA; TFDP1; TFE3; ZNF835; NR2F2; TAF5L; SPIB; CSDC2; HDAC11; TRPS1; AGO2; HSF4; AEBP1; TAF4B; SP100; NR4A1; BNC2; SNAI2; ZNF816; TCF21; FOXA2; PAX6; CREB1; ARL2BP; SPDEF; PRDM4; BRD4; SIRT2; ELF4; PRDM14; EGR2; COPS5; HAND2; SOX9; NFE2L3; SMAD4; MEIS1; DNAJC1; ETS1; FOXF1; CSDE1; RAD21; ZNF576; ZNF783; RNF14; RBBP7; CHD7; NFATC3; CBFA2T3; HIRA; HDAC9; ZNF180; TERF2; NFIC; PGR; SHOX2; TBX21; NR4A2; BACH2; SP140L; NEUROD6; ACTL6A; NR2F1; TFEB; NR0B1; TADA3; CBFB; RB1; NKX3-1; CDC5L; DLX2; TRIM29; ZFPM2; PRRX1; WWTR1; JUNB; ZNF589; KLF9; ZNF148; SLC2A4RG; MTDH; TCF7L1; SUMO1; MECP2; TCF12; NCOR2; TGFB1; KLF5; PAX5; CEBPB; MYRF; FOXL2; NAB1; C1QBP; FOXG1; GATA6; TDP2; RYBP; TAF9B; ELF5; INSM1; BCL3; HOXD1; ID4; BLM; HMGB2; ATF5; NKX2-2; IRF6; RBBP8; ASCL1; ZFP36L2; RBPMS; KLF6; ERBB4; ID1
Down-regulation	195	NR2F6; CERS6; RFX5; ZNF292; CDK8; BAZ2B; SUPT7L; BTG1; IRF7; HIC2; SAP30; ARID1A; NCOA4; DRAP1; ZMYM2; TSG101; GTF3A; RUVBL2; NFKBIA; POU5F1B; RCOR1; ZNF443; BRWD1; ZMYND8; SETD3; PHIP; TCERG1; GATAD2A; ZNF184; SCAI; TAF10; NLK; USF2; SSBP3; ZFHX3; ZNF593; MSX1; HMGB3; SIN3B; ZEB2; ZNF165; DDX17; TRIM28; ZNF432; PCGF3; SFPQ; ADNP; PCGF1; LPIN2; EMX2; TP53; HIPK1; NEDD8; MAZ; MXI1; CBX3; HLTF; HDAC6; BRD3; ZNF544; ELF2; PCGF2; MYT1L; EDF1; CAMTA1; NANOG; IKBKAP; ORC2; MGA; HMG20A; ZNF266; ADNP2; PREB; SMARCA4; CALR; ITGB3BP; ZNF14; NUP62; JARID2; CHD1; PSIP1; LIN28A; HOXB7; ZNF175; ENO1; DNMT3B; RORA; BATF; TWIST1; TRAK1; TBL1XR1; ZNF551; ZBTB20; SOX12; AHR; ZNF124; HSF2; ZNF423; USP16; PATZ1; ERG; ZNF44; PHF20; TTF1; SNIP1; ZNF133; CENPF; HDAC5; FUBP1; PHF1; FOXO3; FOXD1; TEAD4; RREB1; PHOX2B; JUP; GLI3; LYL1; CRY1; PA2G4; CTR9; TRIM27; HMGA1; MED6; DNAJC2; RBBP4; PAWR; SNW1; ARID4A; SERTAD2; ZBTB18; TRIM32; KDM2A; IRX5; TRIM22; KDM5A; CHD8; BRD8; AFF1; HSBP1; YWHAB; SMAD6; SETD2; CNOT2; NELFB; TAF1D; HDAC2; ZNF711; DPF2; NPM1; TGIF1; ZNF24; ELK3; REPIN1; ZNF304; TOB1; MNDA; ATF4; TRIM16; TULP4; RBBP5; CUX1; KAT7; NR1H3; ZNF43; CTBP2; TOX; HOXB6; CARHSP1; BASP1; MYCN; REL; TFAP2C; ZNF394; SAP18; RNF6; NR2C1; TSC22D2; ZNF580; BAZ1A; TSC22D1; EZH2; HLF; HMGN3; RUVBL1; ZNF160; NR1H2; ATF3; FOSB; NFKBIB; TRIP6; MEF2C; ZNF586; CEBPA; PPARG