Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID77615 (+/-)-7-hydroxy-2-(n,n-di-n-propylamino)tetralin GSE92742 FIBRNPC Human 6h 10uM EID0453
Types Number Response transcription factors
Up-regulation 67 PIAS4; EGR4; SOX18; ING4; CNOT3; CEBPD; GTF2I; JUP; XBP1; SOX13; PBX2; MXD1; ZSCAN18; ZFHX4; MEOX1; PARP1; TAL1; MED14; CALR; CREB3L2; ARID3B; FUBP1; PAX6; PROX1; ETS1; SOX9; ZNF177; ZNF83; CUX2; TAF9B; ZNF711; INSM1; FOXG1; SOHLH2; ZNF512B; NFE2; DDX5; CBFA2T3; NFKB2; ZNF415; ST18; TOX; KLF6; SOX11; FOXF2; TCF7L1; NKX2-2; EGR2; EGR3; SOX17; RBBP7; ZNF232; FOXF1; IRF1; ZNF589; INSR; FLNA; ATF3; NFATC3; MEIS2; KLF10; ID4; WT1; TCF4; IKBKAP; ETV1; PEG3
Down-regulation 121 ATF1; USP22; RNF6; THAP10; REPIN1; SP3; ING3; ZZZ3; BRD3; USF2; ZNF267; OSR2; HIF1A; AHR; NR2C1; DDIT3; ZNF408; SNAI2; ZNF84; BCL10; HIPK1; JAK2; MED17; GMNN; THAP1; HOXA10; ZNF430; PHF20; RYBP; SETD2; PTTG1; BLM; RREB1; SP140L; SMAD2; CRY1; MITF; SUZ12; BASP1; TTF1; TCEA1; TRIM32; NCOA4; HTATIP2; DEK; CBX3; NRIP1; TGIF1; ZBTB38; HMGN3; CDYL; NFIB; MBD2; TMF1; CENPF; ZNF329; ZNF394; CDK9; CTNNB1; ING2; HOXA5; TRIP6; MNAT1; ITGB3BP; SUB1; SMARCA4; CEBPG; PAX5; ZNF468; GTF2IRD1; MAFB; NFKBIA; BTG1; PEX2; BIRC2; SIAH2; APEX1; TP63; SIX2; CERS6; RNF138; SAP30; FOXN3; HSF2; FOXO1; ID3; ZNF652; RBBP8; SPEN; RLF; MAF; ZBTB16; ELK3; ID2; ETS2; TBX3; SMAD3; DACH1; NR1D2; KLF2; HOXC6; SCAND1; MLXIP; STAT6; PBX3; ZNF146; ZNF721; ZEB2; GTF3A; HOXC10; ZBTB18; NR2F2; SMAD7; KAT6B; AFF1; SOX4; IRF8; TBPL1; ZFPM2; ZIC1; KDM5D