Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77600	Suramin	GSE92742	FIBRNPC	Human	6h	10uM	EID0453

Response Information :

Types	Number	Response transcription factors
Up-regulation	177	GATA3; NR3C1; ZNF215; KDM5C; ZFP36L2; MED12; HOXB5; CDX1; TFDP2; ZNF93; SOX13; KMT2B; ZNF43; PROP1; POU2AF1; SPIB; SMARCA1; NOC2L; MED14; ZNF253; ZNF335; AIRE; PBX2; FOXP3; CEBPE; MED25; NR5A2; TLX1; DLX2; ZNF177; RAD21; MBD4; NAB2; NHLH1; ESR1; PAX1; GABPA; ZNF273; BTG1; HDAC5; IRF6; FOXE1; HCFC1; NR0B1; HMGB3; FLI1; SUPT3H; TCF7L1; CDK2; PBX3; ZSCAN9; KLF15; NFX1; NKX2-1; GATA2; PRDM1; TCF3; HOXA4; ZNF345; PIAS4; CREB3L2; PRDM14; HEY2; HOXA3; ZNF85; SOHLH2; RXRG; EZH1; NR1H2; FOXD1; NFE2; ZKSCAN4; TRPS1; SNAI1; GTF2I; SIX3; MMS19; HMGB2; IRX5; LIN28A; ZIC3; ZNF711; GFI1; CHD7; ZNF350; CD3D; NFKBIA; HBP1; RBBP4; IRF4; TAL1; BTF3; CTBP2; SSBP3; LHX6; MXI1; SAFB; ZNF165; TERF1; TWIST1; ZNF117; HOXC4; EPAS1; TCF7L2; CUX2; ZNF331; XBP1; HOXB6; DNMT3B; ARID3B; MDFI; ZNF611; PRPF6; ZNF544; HIPK2; KLF7; CNBP; SUMO1; INSM1; ZNF665; ALX1; TFAP2A; JUP; PPARD; MYB; PNRC1; ZFX; RUVBL2; INSR; SIM2; STAT4; CARHSP1; NFATC4; TGFB1; ZNF22; BCL11A; DACH1; HSBP1; MNDA; ZNF426; ZNF195; ZNF532; MLXIP; ZNF589; ID4; ZNF516; E2F5; ARID5B; OSR2; NKX2-2; SATB2; WT1; BHLHE41; DMTF1; POU4F1; ELK3; ETS1; CBX5; HIRA; AEBP1; VDR; ERG; HEY1; C1QBP; HOXC6; ID1; TXNIP; DLX5; HOXA11; ZNF91; RB1; MEIS2; PAX6; TCEB2; RUVBL1; RHOA; CITED2
Down-regulation	207	PCBD1; USP22; NUP62; CRK; ZNF267; KDM5D; HLF; UBP1; EED; ATF2; HDAC6; PATZ1; IRF2; HIPK1; HOXD1; ATF1; TSC22D4; ZBTB38; ZFP64; NFIB; ETV5; ZNF358; ZNF12; AHR; RNF6; THAP10; DEK; EHF; RYBP; TFAM; FOXO4; BAZ1B; ZZZ3; SIX1; SP3; PHF20; RXRB; TRIP6; TRIM22; FOXJ3; KLF4; CHD1; REPIN1; SIX2; C1D; SP140L; MITF; CDYL; SREBF1; PBRM1; MEOX1; ZFY; RNF138; KAT2B; CREBL2; HIVEP2; PLAGL1; COPS2; SP110; CREB5; LHX1; SETD2; SMARCD3; USF2; PBX1; PIR; SP100; BBX; ZBED1; CBX7; ERCC3; BCL10; NFE2L1; CBX6; TOB1; GTF2IRD1; ZBTB24; CHD3; BLM; REST; SUB1; ZNF217; MSC; BASP1; CENPB; ID2; MED23; RBBP5; HDAC3; SMAD4; PHF2; ZNF148; NCOR1; SMAD6; SMAD3; ASCL1; RBPMS; HIVEP1; SMAD2; NFIC; VEZF1; CTR9; SAFB2; NFATC1; NPAS2; NFYC; MEIS1; ATF7IP; CSDE1; MAGED1; KLF9; RUNX1; TSC22D2; LPIN2; NR2C1; TFEC; RUNX3; BAZ1A; DNAJC2; NR2F2; CHD9; ING3; TCF12; ZNF24; LDB1; TSC22D1; TRIM32; DPF2; BMI1; FOXN3; CBX3; HOXB13; NFAT5; ARID4B; SPEN; SNAI2; UBE2B; CBFB; SMARCA4; SCAND1; TLE1; BCL6; MAML1; SFPQ; MAF; FOSL2; KLF2; NAB1; DNAJC1; AES; BRPF1; CRY1; BRD8; ZFPM2; ZKSCAN1; RNF4; TOX3; TADA3; CREB3L1; CTBP1; NFIL3; ZFHX3; ELF1; MECOM; KLF5; ERBB2; PHF8; APEX1; SMAD7; NR4A1; FOXJ2; BIRC2; ZEB2; NCOA6; NKX3-1; CERS6; TLE4; ELK1; CLOCK; ZNF576; SIAH2; TRIM16; ZIC1; BATF3; NR1D2; MED13; IKBKAP; NRIP1; HMGN3; IRF8; SMARCA2; PITX1; PQBP1; ZMYM2; ZBTB16; HOXC10; ENO1; FOXC1; TRIM29; RORA; ETV1; GLI2; SOX4; TBL1X; CEBPA; PEG3; SUV39H1