Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID77527 Mk-801 GSE92742 FIBRNPC Human 24h 10uM EID0452
Types Number Response transcription factors
Up-regulation 67 TSC22D1; CBX7; PBX2; PIAS2; TEAD4; ZNF586; BCL11B; ARID5A; KLF5; NR3C1; ID1; NR4A3; CUX1; TRRAP; SMAD6; DNAJC1; SOX9; TBL1XR1; MYCL; CRYM; SP3; TLE2; FOS; NCOR2; IRF9; EGR2; NCOA1; SMAD7; TP63; MNDA; FOSB; FOXF1; MYBL1; MAF; LITAF; PLAGL1; SATB2; SMARCA2; SIX2; RELB; AES; HMGB3; EYA1; SIX1; DACH1; BASP1; NR4A1; EHF; SUV39H1; HOXC10; FOXJ3; ELF5; BHLHE41; TBX2; SNAI2; SMAD4; KLF13; POU2AF1; ATF5; TRIM29; TOX3; HTATIP2; STAT1; ZIC1; TCFL5; GATA3; CRK
Down-regulation 31 PEG3; PHF20; MYCN; PBX1; PRPF6; ELK3; RUVBL1; STAT5A; VGLL4; MEIS2; BRD7; SP110; MYRF; SOX10; HIC2; ERG; KLF11; NR2F6; AEBP1; MKL2; PITX1; HLF; PAX6; HHEX; ZNF652; APEX1; HMG20B; WWTR1; CERS6; ZBTB18; IKZF1