Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77507	Tolcapone	GSE92742	FIBRNPC	Human	24h	10uM	EID0452

Response Information :

Types	Number	Response transcription factors
Up-regulation	194	E2F2; MTF2; MNAT1; THAP1; EGR2; CHD4; NR5A1; CBFA2T3; E2F5; KMT2D; NFE2L3; TERF1; ZNF440; NR3C2; NR4A2; SNAPC4; ELF3; HESX1; NR0B1; GATA6; POU3F4; MED13; DOT1L; EP300; DR1; POU4F1; ZNF235; HOXA3; DNAJC1; CBX2; CEBPE; NR1I2; HMGN3; MLLT10; ASCL2; VHL; TSHZ2; SRF; ZBTB7C; BCOR; CHD7; WDR77; RCOR1; NFATC1; E4F1; ZNF141; RELB; MAFG; PIAS4; TEAD4; SSBP2; BHLHE41; NRBF2; ZNF3; WNT4; ZNF41; OVOL1; IRF7; ZNF764; KLF5; ZSCAN16; HEY2; PBXIP1; ZNF701; CHAF1B; SATB2; MLXIP; FOXO1; PROX1; CDK8; ZNF623; EYA2; ATOH1; MYCL; HOXD9; ZNF212; STAT2; MXD1; TRIM33; SOX3; SOX18; BLZF1; POU2F1; TRIP11; TAF7; PRDM12; WWP1; WT1; CBX7; ZNF112; IFNB1; THAP9; MYBL1; ZBED2; ZNF34; PRDM10; ZNF674; SMARCA5; PAWR; MED14; ZNF248; GCM2; VDR; TBX1; MED7; EN2; CAMTA2; PLAGL2; ZNF573; ZNF254; ATF3; TSC22D1; SPIB; TOX3; ZNF214; CTCF; PKNOX1; REPIN1; CIR1; RBL1; ATF7IP; SAP130; CDIP1; HIC2; MYB; PIAS1; UBE2I; CDX1; RERE; ZNF562; SNAI1; CREB3L2; TRIM24; IRF5; ZMYND8; GFI1; PGR; ZFP69B; ZFP36L2; ZNF682; EGR4; KDM5D; DNMT3B; ZNF117; SERTAD2; ZNF12; JAK2; KLF2; ZNF44; NR4A1; PITX2; ZNF331; FOXL2; HNRNPD; DAXX; HMBOX1; ERF; JARID2; ELF5; HIRA; ZNF136; BCL10; CEBPZ; CCNE1; UBE2B; BTG1; NCOA1; ZNF571; SAP18; RBPJ; CUX1; LIN28A; ZNF165; RLF; SUB1; DACH1; KLF4; HOXD1; ZBED4; REL; NFATC3; INSM1; NANOG; JUNB; TCF7L2; WHSC1; NKX2-1; SOX9; KLF6; SOX17; GATA3; TXNIP; HMGB3; CRK
Down-regulation	258	ID2; SCAND1; CREB1; PHF20; SIN3B; ZNF593; BRD8; CDK9; HOXB6; ZNF688; HOXB5; BRD7; CHD9; FOXF2; TFDP1; TRIP6; KAT6B; ZNF266; DEK; TAF6; ZNF76; PDLIM1; HOXB2; SLC2A4RG; LDB1; MEIS1; HOXB3; ATF2; ZNF580; BASP1; STAT6; RB1; TCF12; ZNF35; MED20; TRIM28; HOXB7; PBX1; FUBP1; PBRM1; HMGA1; UBP1; HOXC10; PHF1; THAP11; RBM39; TRAK1; TAF10; HOXA10; ZNF384; PRRX1; WIZ; JUND; BTAF1; MYRF; ZNF544; ZNF175; ZNF528; GLI3; TRIP4; TBL1X; ZNF432; MDM2; PIAS2; LZTR1; IKZF5; SETD2; ELK4; TAF1C; NR1H2; PAXBP1; ZSCAN18; ZNF646; TBP; RXRB; CTBP1; PMS1; MMS19; USP16; NR2F2; NCOA4; ETS2; SP3; CIZ1; MTDH; TOX4; PCGF1; SMARCA4; MECOM; ZFP30; MYNN; RFXAP; TRAF6; ZNF587; COPS2; CNOT3; NFYB; ELK3; PTRF; SMAD3; THAP4; HOXC6; SHOX2; ASXL1; CBX3; CNOT2; LYL1; TADA3; NPAS2; ZZZ3; PAX8; MEIS2; NELFB; LOXL2; TCF25; ZNF692; SREBF1; ELF4; SOX2; PFDN5; SALL2; TRRAP; HHEX; NFIB; CHD3; ZNF574; ZHX3; ERBB2; BAZ2B; NPM1; ZNF552; TRPS1; TAF9B; SMAD6; MKL2; CENPB; SMAD4; NFYA; ZNF83; TFEB; BCLAF1; ARRB1; ZBED1; AHR; EHMT2; GTF3A; SMARCA1; CREB5; KLF12; ZMYND11; CNBP; RNF10; PSMC3IP; RUVBL2; NR2C1; HDAC9; ZFHX4; HLTF; DNAJC2; ZNF816; ZNF512B; TRIB3; ISL1; ID3; BATF3; ZBTB11; RREB1; ZNF652; ZBTB38; ATF5; SIM2; DMTF1; ZFX; POU2AF1; RYBP; ZNF32; HOXA5; RUNX1; ARID4B; CTNNB1; PRRX2; SIAH2; TLE1; CDC5L; DEAF1; ZNF589; RAD21; HIVEP1; HOXB13; ARID1A; TGFB1I1; SP100; SMAD7; BRD3; ZFP36L1; RNF141; ZNF43; PAX5; ARNTL2; ZMIZ1; KMT2B; MEOX2; PCGF2; SAP30; ZNF672; PAX6; TCF21; PPRC1; RAN; CREB3; ZFHX3; ZNF665; HSBP1; FLNA; WWTR1; CBX6; NKX3-1; STAT4; GTF2I; ABL1; PEG3; SMAD1; SMAD2; FOXF1; HMG20B; RFXANK; ZEB2; DDIT3; ZMYM2; RNF138; HMGB2; HEY1; CTBP2; BIRC2; CRY1; BNC2; POLR2A; AFF1; NKX2-2; SNAI2; MSX1; RORA; ZNF302; SMARCD3; MBD2; MAFB; NFAT5; NR3C1; ID1; EMX2; ZBTB18; SUV39H1; ZIC1; TCFL5; ADRB2; TBX2; IKZF1; PPARG