Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID77459 Aminobenztropine GSE92742 FIBRNPC Human 24h 10uM EID0452
Types Number Response transcription factors
Up-regulation 88 SSBP2; NR2E1; ELF4; TBL1X; MEIS2; EGR2; SUV39H1; BRD4; PBX2; RSF1; LITAF; LPIN2; TEAD4; NRBF2; ZNF263; SOX9; ZZZ3; ZNF202; SOHLH2; TBX21; SUB1; MYNN; ZNF3; PLAGL2; SPDEF; EYA2; ERBB4; TDP2; AR; TAF1D; HEY1; HOXB2; FOXI1; HINFP; FOXG1; STAT4; ZNF12; ZNF500; KDM5D; FOXN3; HMGA1; FOXM1; ZNF350; ZNF232; RBPJ; ZNF512B; DDX17; DLX2; MECOM; CCNE1; MAFB; MYBL1; ZFP36L1; NR2F2; PQBP1; CD3D; RORA; BTF3; TCF21; ZNF239; ZNF217; GTF3A; NR2F1; DDIT3; ATF4; FOXA1; ABL1; FOXF1; MEOX2; ELF3; POU2AF1; ELF5; GATA3; ARNT2; ZNF43; DAXX; SMARCA1; CDK2; JUND; TRPS1; IFI16; YBX3; SMAD7; ZNF91; NKX3-1; SOX11; ESR1; PEG3
Down-regulation 89 CREB1; KLF9; ZSCAN18; KLF11; TULP4; TOB1; BRD7; NR4A2; NFE2L1; BATF; BASP1; ID2; LYL1; SKI; HSBP1; NR1D2; PROX1; ARID4A; ARL2BP; MYCN; KLF2; CHD9; ING3; NR4A3; PDLIM1; PTTG1; SOX4; TMF1; NFATC4; BTG1; TXNIP; ZNF264; NFKBIB; ID3; NR1I2; ASCL1; ZHX3; FOXE1; MXD4; NAB1; ZBED2; ZNF124; ZMYM2; KLF6; EBF2; ZBTB20; TBL1XR1; CDX1; MYB; SPIB; HTATIP2; SFPQ; ZNF665; KLF10; IRX5; NCOA1; IRF4; CHD7; RBBP4; HMGN3; SAP30; ATF5; ERG; ZNF430; MED6; MED1; TSC22D2; RNF141; ZFP36L2; BCLAF1; HDAC4; TFEC; MBD2; ZEB2; ZBTB38; ZNF165; NKX2-1; HMG20B; BIRC2; ST18; ZSCAN31; AEBP1; HLTF; PIR; SMAD2; INSM1; TCFL5; ID4; IKZF1