Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77458	Alendronic-acid	GSE92742	FIBRNPC	Human	24h	10uM	EID0452

Response Information :

Types	Number	Response transcription factors
Up-regulation	238	ZNF586; IKBKAP; ZNF131; SNAPC4; ZNF587; ZNF211; KDM5A; NR2E1; ZNF329; ZNF551; ZMYND8; ZNF324; HOXD1; ZNF419; ZNF134; TAF4B; ELF4; TOB1; HOXD3; PLAGL2; CLOCK; EP300; ZNF440; ZNF671; SSX1; TOX; ZNF45; MBD4; TULP4; ZNF3; NKRF; RBL2; FOXG1; NRBF2; HMBOX1; PIAS3; CXXC1; RFX7; ZNF223; MECOM; ZNF711; ZNF654; TRIM32; HMGN3; POU2F1; ZNF224; NLK; ZNF8; MYBL1; SMARCA2; ZNF160; ZNF721; ZNF227; TTF2; MLLT10; ZNF235; ZNF764; REPIN1; ZNF222; ZBTB44; ZFP36L2; LHX6; KMT2A; MECP2; MEOX2; ZNF550; NFIC; TCF7L1; MXD4; ZXDC; CREM; ZNF778; ZNF84; MBD2; CHD4; HSF2; RBPJ; ZNF354A; MZF1; NR1H4; ZNF701; CAMTA1; ZNF226; SIX3; RBL1; CHD9; NR4A3; NFRKB; ZSCAN9; SUV39H1; GATA6; MLXIP; TRIM24; THAP1; DMRT1; GFI1; HOXA1; ZNF304; IKZF3; IRF3; FOXA2; NSD1; TFAP2C; ZNF444; ISL1; PEX2; ZNF574; ZNF225; ZNF83; SP2; SOHLH2; TWIST1; ZNF493; ZNF787; HDAC4; ZNF44; TMF1; THAP10; ZNF10; ZNF22; ZNF573; ZNF512B; WHSC1; TCF12; ZKSCAN4; MED14; ZNF142; CHD2; TBX2; ZNF536; URI1; ADNP2; HIPK2; SHOX; CUX1; PHIP; BAZ2A; ZNF580; FHL5; MEIS2; BCOR; PCGF1; NFX1; SSBP2; NR2F2; TTF1; ZHX3; ZNF141; KDM5D; SOX17; NCOR1; PIAS4; TAF9B; ZNF529; KLF5; SAP130; DNAJC1; MAFG; ELF3; TRIM33; ZNF611; ARID1A; ZFHX3; ZNF180; MNDA; EYA1; MYT1L; TGFB1; IKZF1; NKX2-1; ZNF492; FOXJ1; ZNF423; BRIP1; RARA; ZNF136; TRIM28; YEATS4; RLF; SCAI; CREB3L1; ELF2; ZNF236; MNT; PIAS1; ZNF652; ZNF93; RNF4; DNMT3B; ARL2BP; RUVBL2; IRF4; WT1; HOXC6; ZFP69B; KLF13; ZNF217; LEF1; INSM1; ERBB4; EN1; BCLAF1; CEBPZ; RNF138; PCGF3; AHR; FOXC1; FOXM1; RUNX3; MITF; BRD4; ZNF107; TOPORS; STAT4; TXNIP; CITED2; FOSL2; ZNF165; WDHD1; ZNF281; NR1D2; KLF6; ZNF331; RBPMS; GATA3; ZNF91; ELF5; ZBTB16; ARNT2; TRPS1; CERS6; TCF7; ATF5; HMG20B; SOX11; NFATC3; MYB; CRK
Down-regulation	243	VGLL4; XRCC6; IRF7; CREB1; TRIM16; BRD8; ZNF532; NEDD8; SREBF2; MAFF; TRIP6; RNF10; ZHX2; MAF; BASP1; PBRM1; EGR3; MDFI; VDR; GTF2IRD1; TAF9; SMARCB1; CARHSP1; ZBED1; RBM39; PSPC1; MLX; MAX; EZH2; HOXB13; ZNF506; LPIN2; HMGB1; TBP; KAT2A; HIF3A; SREBF1; DEK; ZNF148; TERF2; HIPK3; MYCN; SMAD1; CERS4; ZBED2; TRIM22; ARRB1; TBX3; TBPL1; LOXL2; UBE2L3; PTTG1; ENO1; ZNF146; SP110; PARP1; SETD3; ZNF266; MED13; RBBP4; BRCA1; NFYA; SRCAP; GTF3A; ZNF32; TAF5L; IRF6; ETV7; ENY2; RXRB; RB1; IRF9; TEAD3; TSC22D4; PSIP1; DEAF1; BRD7; SF1; RNF14; PRPF6; ALX3; TCF25; RNF141; MXI1; TGIF1; IRF8; YBX3; FOXK2; HOXB3; HBP1; HLX; CDK8; HMGB2; PUF60; CCNA2; ZNF219; BARX1; PHF1; RXRA; THRAP3; ATF1; HMGXB4; ZNF250; CIC; TRIM27; RREB1; NFIL3; NCOR2; TFEB; ID3; SALL2; TRIP4; CDK9; ZFP36L1; TRIP11; PMS1; NFIB; ZNF35; TLE2; PROX1; CNOT2; ZNF528; BTAF1; MDM2; PHF20; CTNNB1; TCF15; MED21; PITX1; TCF3; NAB1; GCFC2; PEG3; PSMC3; ZBTB38; NAB2; MAFB; NRIP1; STAT1; CRTC1; ZFX; FOXN3; ARID5A; MED6; ZNF143; ZEB1; SPI1; PBX1; STAT6; RAN; TULP3; NFKBIA; RUVBL1; ETV1; TFCP2; CREBL2; TAF6; E2F3; BNC2; NFYC; IRX4; SRF; CNBP; BACH2; ZNF16; BATF3; AIP; CDYL; SOX9; ZNF292; ASH2L; RNF111; FOXO1; MED7; ARNTL2; NPM1; ARID4B; BARX2; SMARCD3; PPARD; CTBP2; ZNF589; KLF11; RELA; ELF1; ATF7IP; TAF10; TDP2; BAZ1A; TRIB3; ATN1; RBBP7; HEY1; HMGA1; ZMIZ1; TCEA1; PDLIM1; TRIM29; SALL1; BRD3; PCGF2; NCOA4; SAP30; IRF1; ZNF467; COPS5; EHF; PAX5; MYC; RYBP; HHEX; ZNF24; NFKB1; ZMYM2; COPS2; PURA; ELK3; TGIF2; CBX6; TCF4; ASCL1; HMGB3; ZKSCAN1; SIAH2; TBL1X; ZBTB1; KLF4; MSX1; ZSCAN31; SMARCE1; SAP18; NKX3-1; NR2F1; CBFB; MAGED1; HLTF; HTATIP2; NR3C1; TCFL5; TOX3; ZIC1; PPARG; RELB