Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77430	Reboxetine	GSE92742	FIBRNPC	Human	24h	10uM	EID0451

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	DNMT1; CTBP2; TFAP2A; VPS72; ZNF74; SPDEF; NKX2-1; TFAP2C; ZNF85; SOX11; KDM5C; SRCAP; ZNF331; NR2C1; GRHL2; TFEC; HBP1; ZNF215; LZTR1; GMNN; TP73; BARX1; CCNH; RBPMS; PRDM14; ATN1; THAP7; ARID3A; SOX2; HDGF; MYBL2; ZNF467; ZNF232; ZNF623; IRF6; AR; TAF5L; TRPS1; HOXB5; PIAS4; HOXD1; ST18; TRIB3; HIC2; XRCC6; TTF2; HDAC5; FOXF1; CREM; MED15; FOXF2; GLI3; CDK2; PHIP; ZNF273; PFDN5; RBFOX2; TEAD4; HIPK1; SETDB1; ZNF43; ZNF83; IRF8; RBPJ; ZBTB16; CALR; FOXE1; NANOG; ESR1; IRF9; DLX5; SMARCB1; MYBL1; NR0B1; HHEX; FOXO1; BCL11A; SSBP3; EPAS1; IFI16; NR1H4; HOXB6; TDP2; WWC1; IRF7; SALL2; LIN28A; NFE2; HMGN3; HOXB2; ZBED2; ZFPM2; OSR2; ZNF117; ARNT2; PSMC3; ARID5B; BNC2; ZNF430; CITED2; NKX3-1; LITAF; ELF3; TXNIP; ZFP36L2; EHF; MYRF; MEIS2; ZBTB18; PEG3; HMG20B; CRK
Down-regulation	129	KDM5D; NR1D2; ID2; ELF1; AATF; TLE1; NUP62; KLF6; MBD2; PURA; SMAD2; SP2; HCFC2; TBP; ZFP64; HNRNPD; MED1; RBM14; ATF1; TMF1; SOX4; UIMC1; POLR2A; ASCL1; KAT7; CTR9; CCNA2; MYCN; CBFB; ZBTB43; TSC22D2; C1D; EP400; NFKBIA; MAGED1; ALX1; CRY1; ZNF532; ZFY; CARM1; NCOR2; KLF2; SNW1; NR1I2; NR2F2; ING3; ZBTB11; SERTAD2; BATF3; ZNF226; TRRAP; IRF1; HIVEP2; LEF1; E2F6; NCOA1; SIX1; ZNF148; NCOA6; SF1; REPIN1; WWTR1; ZMYM2; URI1; ZBTB38; EDF1; KLF13; ID3; HOXA1; NFAT5; TEAD1; TSC22D4; ZNF432; PHF8; ELK3; PRRX1; FOSL2; BBX; ZEB2; TFEB; MSC; PCGF2; SUB1; YWHAB; JUNB; RFX5; ZFHX4; SFPQ; RNF10; PIR; SATB2; MEOX1; BCL3; ENO1; CHD7; FLNA; ZMYND8; SMARCA2; MAFB; ZBTB20; NFKB1; FOXJ3; BMI1; HSBP1; TRIM32; KLF4; IRF4; FOXC1; TRIM29; NR2F1; KLF10; BRD2; HLTF; FOXD1; KLF9; SIAH2; KDM5A; BASP1; ETV5; CREB3L2; MSX1; SMAD7; HTATIP2; SUV39H1; ZIC1; NFATC3; IKZF1; RELB; ZNF586