Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID77427 (+/-)-7-hydroxy-2-(n,n-di-n-propylamino)tetralin GSE92742 FIBRNPC Human 24h 10uM EID0451
Types Number Response transcription factors
Up-regulation 73 SOX11; ZNF232; NKX2-1; ZBED4; ZNF112; NFIL3; TTF2; ZNF74; RUNX1; TULP3; CSDE1; NFE2L3; CALCOCO1; CHAF1B; TGFB1I1; MYBL2; SPDEF; CEBPD; ZSCAN16; ZNF623; SOX3; SOX13; CIZ1; WWP1; BRIP1; TBX1; ZNF580; TFAP2C; CERS4; E2F8; PFDN5; RRN3; ZFHX3; TRIM24; CALR; POU2AF1; KAT2B; RBPJ; ATN1; THAP10; SOX10; HMGA1; ZNF107; FOXF2; RSF1; MXI1; INSR; ETV5; RORA; CITED2; HIPK1; LEF1; PBX3; TRIM29; MNDA; MYBL1; TRIB3; LITAF; ZKSCAN1; ESR1; PSMC3; ELF3; BNC2; ISL1; TWIST1; TOX; SMAD1; ZIC1; BHLHE41; PEG3; ARNT2; HMG20B; CRK
Down-regulation 96 SCAND1; NR1D2; SMAD2; SNW1; ING3; NFATC1; AATF; PREB; VEZF1; PAX6; ZBTB38; SNAI1; BCL10; DBP; TAF10; NR4A1; RBM14; KLF9; KLF6; SKI; LMCD1; IKZF5; FOXN3; SMAD5; BBX; CREM; ZNF148; HIVEP2; DNMT3B; ZNF721; CHD1; ZMYM2; HOXC6; ENO1; RFX5; MAFB; ZNF587; JARID2; TOB1; MSX1; CTR9; FOSL2; RNF4; ZNF160; IRF4; SFPQ; NKX2-2; ZNF143; SMARCA1; MAF; TAF1D; NFKB1; BCLAF1; BANP; HSBP1; APEX1; MXD4; OSR2; BCL11B; TXNIP; NFAT5; RBL2; HTATIP2; SAP18; TCF7; SATB2; NR4A3; STAT4; HOXA1; RNF138; ARID4B; TSC22D2; ZMIZ1; IRX5; NAB1; SMAD7; MYCN; MEIS1; TBL1X; ELK3; CREB3L2; FOXG1; ZSCAN18; MYB; ID3; ZBTB20; NFATC3; SUV39H1; ZBTB18; ZNF586; DACH1; EMX2; IKZF1; RELB; GATA6; ADRB2