Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77425	Carbidopa	GSE92742	FIBRNPC	Human	24h	10uM	EID0451

Response Information :

Types	Number	Response transcription factors
Up-regulation	151	RB1; DNMT1; SOX13; VPS72; SPDEF; UTF1; TFAP2A; ATN1; ZNF74; CCNH; TFAP2C; CDK2; TP73; NFE2L3; GMNN; TTF2; TERF1; NANOG; NKX2-1; ZNF232; CTBP2; POLR3C; WT1; CERS4; PRDM14; TCF20; HOXB6; XRCC6; KDM5C; ACTL6A; BARX1; TULP3; CALR; ARID3A; HBP1; SSBP3; HIC2; MKL2; FOXH1; THAP7; ZFHX3; TCEA1; ZNF215; HOXB5; LZTR1; ZNF273; SUPT3H; SP3; ARID1A; ZBTB16; GON4L; SUPT6H; NR5A2; ZNF195; CBX7; PAXBP1; USP16; MED15; TRIB3; FOXO1; PIAS4; MYBL1; JUP; SAP130; MECOM; ZNF423; SETDB1; PRKDC; RRN3; ZNF331; HDAC1; TGS1; ZNF200; LITAF; KLF7; TRIM33; RBPMS; POU5F1B; PHIP; HDAC5; SALL2; TRPS1; CIR1; TFEC; CDK9; CNOT2; CD3D; PIAS3; MED17; FOXF2; PBX1; GRHL2; ILF2; HIPK2; HOXD10; CHD4; CEBPZ; ESR1; IRF3; MED14; TFCP2L1; ELF3; OVOL2; E2F8; IRF6; CITED2; BNC2; ZNF665; ERBB4; CBX6; REL; DLX5; CAPN15; HOXB2; SIX3; EPAS1; IRF9; BCL10; PSMC3; FOXG1; SP140L; DNMT3B; RBBP8; CHD9; HHEX; ARID5B; NR1H3; CBX5; FOXF1; HOXD1; INSR; ID4; BHLHE41; HIPK1; LIN28A; KAT6B; ETV5; ZZZ3; ZNF124; ARNT2; ZNF430; ZMIZ1; ZNF107; MYRF; HMGA1; TOX; EYA2; UBE2I; HOXC6; HMG20B; CRK
Down-regulation	133	PURA; KDM5D; MBD2; HCFC2; BASP1; MTDH; HOXA10; KLF6; MAGED1; AATF; MLXIPL; BAZ1A; NFATC1; SETD2; NR1D2; LMCD1; CRY1; ZEB2; SMAD2; NPM1; DNAJC1; RBM14; SKI; ZKSCAN7; TSC22D2; CBFB; ZFP64; MYOD1; USF2; ZNF536; REPIN1; ELF1; SOX11; PTTG1; NCOA4; HNRNPD; ING3; ZNF410; BBX; PAX6; MSL3; NRIP1; EDF1; ZNF148; FOXN2; HIVEP2; INSM1; ZFY; KLF4; ZBTB38; NFKBIB; CDK8; SMAD5; NEUROD1; TLE1; FOSL2; POU2F2; LIMD1; BRPF1; KLF2; ALX1; YWHAB; IRF8; URI1; ENO1; HMBOX1; NFKB1; DACH1; PIAS2; ZNF529; SAP18; EZH2; TCF4; ELK1; ZMYM2; NCOA1; IRF7; JUNB; HMGB2; SP110; IRX5; NR4A1; TRIM16; RNF10; TAF7; NCOA6; MYCN; ZBTB1; RCOR1; TEAD1; ZIC1; UBP1; BAZ2B; MAF; MEIS1; ZNF24; KLF5; NHLH2; MSC; ING2; RNF6; SMAD4; SIAH2; CCNE1; SFPQ; NFIB; TRIM32; ZBTB20; HEY1; HTATIP2; ZSCAN18; ID3; BCLAF1; SMAD7; PPARGC1A; TRIM29; PAX5; SNAI2; KLF9; CUX1; ELK3; BRD2; SATB2; TRIM22; DAXX; NFATC3; FOXD1; KLF10; EMX2; SUV39H1; ZNF586; RELB; IKZF1