Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID77376 Ciproxifan GSE92742 FIBRNPC Human 24h 10uM EID0451
Types Number Response transcription factors
Up-regulation 145 DNMT1; VPS72; SPDEF; SOX2; THAP7; ZNF232; PRDM14; SOX13; CDK2; TFAP2A; HBP1; PHIP; HLX; CTBP2; ATF3; ZNF467; GMNN; MYCBP; ZNF74; ARID1A; MYBL2; ZNF215; CCNH; HDGF; CEBPD; IRF6; GRHL2; ST18; CSDE1; BARX1; JUP; ZNF273; SETDB1; HMGN3; MED15; ZNF623; ZNF580; ZNF34; TCF7L2; ZNF415; KLF11; AEBP1; CBX7; SOX18; TFEC; TULP3; RBFOX2; NR0B2; CBX4; TRIB3; MXI1; TGFB1I1; OSR2; NFE2L3; MITF; TFAP2C; NCOA2; RING1; PRDM2; CERS4; FOXA1; ZNF512B; SSBP3; MLXIP; ILF2; INSR; FOXO1; HIC2; NKX2-1; ZNF133; ERBB4; HIPK1; GATA2; HOXB2; POLR3C; SHOX2; ZNF141; CBX6; MYCL; E4F1; ZNF195; ZNF331; TAF4B; USP16; TCEA1; SOX17; AR; SMARCB1; ARL2BP; CNOT3; SMAD1; CALR; RBPJ; ZNF652; SALL2; ZBTB16; ZNF835; HIPK2; ZNF711; ZFPM2; PITX1; THRA; CNOT6; ARID5B; LIN28A; THAP10; HOXB6; INSM1; MYBL1; DLX5; HLF; ZIC3; HHEX; REL; HOXD1; ZNF117; ZNF43; ZNF107; NKX2-2; PEG3; IRF9; HSF1; TDP2; BCL11A; MEIS2; ARNT2; ZNF665; HDAC9; TRPS1; MYRF; TCF7L1; TP63; NR2F1; WT1; LITAF; MEIS1; TXNIP; ESR1; ID4; TOX; ISL1; POU2AF1; EHF; HMG20B; CRK
Down-regulation 154 AATF; NR1D2; ID2; PDLIM1; BASP1; MED1; ZBTB43; ATF1; ELF1; KAT7; NR3C1; NUP62; MAGED1; VEZF1; PURA; ZFP64; IRF2; MAX; HMG20A; RBM14; NCOR2; NR1I2; TLE1; STAT1; REST; HCFC2; ZNF783; MNAT1; ING1; SMAD2; CDK8; TFAM; EP400; TADA2A; SIX1; C1D; HNRNPD; ASH2L; KLF12; YAF2; HOXB9; BBX; NPAS2; NRBF2; TMF1; CRY1; SFPQ; ZMIZ1; MEF2A; CTR9; KDM5D; LIMD1; EDF1; SMAD5; ZNF189; DNAJC1; BRPF1; ZEB2; HOXA7; SMAD7; ZNF84; TOPORS; ENO1; ZNF532; TSC22D2; MED27; RNF6; KLF6; ZNF432; ZBTB1; ING3; ING2; ZNF226; PHF2; NFYB; POLR2A; SIAH2; NRIP1; DDX5; NCOA4; TAF10; PIAS2; HTATIP2; RBBP4; BAZ1A; MED7; ZBTB38; BRD3; EGR3; SAP18; TP53; SOX9; ABL1; CREB5; ZFP36L1; RNF111; ETV1; JARID2; HMGB3; SP140; ZMYM2; HOXA1; ATF7IP; LEF1; TCF7; ELK3; CITED1; CREB3L1; RNF14; SATB2; BCL11B; SUB1; MED13; BCL10; NFAT5; PQBP1; KLF1; ZNF587; NR2F2; PPARGC1A; LPIN2; PHF8; KLF2; MSC; ZNF22; SALL1; PCGF2; HSBP1; TRIM22; ZNF217; SNAI2; RBBP5; YWHAB; SERTAD2; TRIM32; FLNA; FOXD1; ZIC1; BMI1; NKX3-1; CHD7; ASCL1; KLF10; SMAD4; HLTF; PITX2; TSC22D1; DACH1; TGIF1; NFATC3; SUV39H1; RELB; IKZF1; ZNF586