Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77328	Ingenol	GSE92742	NKDBA	Human	24h	3.3333uM	EID0450

Response Information :

Types	Number	Response transcription factors
Up-regulation	395	THAP11; SOX2; SSBP2; PRRX1; ZNF107; ZNF253; ADNP; RB1; GABPB1; IKZF1; POU2AF1; KDM5B; PARP1; ADRB2; NFKB2; MBD1; DLX5; ACTL6B; MNX1; GTF2I; EHMT1; NCOA2; SP140; MDM2; ZKSCAN7; TFDP3; ARID1A; LIMD1; LITAF; POU4F1; SALL2; TRRAP; ZNF85; ZNF711; STAT2; TAF4; ZNF512B; TAF1A; ZNF391; ZNF500; URI1; HLX; CDK9; MKL2; TWIST1; FOXF2; CRYM; ZNF692; MYT1L; BMI1; SOX13; MTA1; HEY1; GRIP1; TULP4; CBFA2T3; CENPB; ERBB4; ZNF93; TFAP2C; IRF4; NCOA1; ZNF816; GATA2; SAFB2; DMTF1; CAPN15; PBXIP1; RORA; RARG; SPDEF; SSX7; MYRF; ZHX2; ZNF225; PRDM13; FOXN3; ZNF117; CHD2; ZNF273; GBX1; EYA2; RARB; PAX6; TAF6; SRY; BCOR; KLF3; TTF2; STAT3; CREM; ZFP69B; GABPA; ZNF536; BCL11A; IKZF5; EMX1; ZNF227; FOXE1; IRF3; ZNF701; SKIL; PAX5; FOXA2; PPARD; NOC2L; ZNF343; CBX7; ZNF586; ZNF257; PIAS2; ZNF43; FUBP1; ZBTB25; SUV39H1; CCNE1; MEIS2; CEBPZ; SETD2; WHSC1L1; NRL; BRD7; ZNF195; ZIM2; PRDM1; FOXB1; TLX3; ZNF217; TBX21; THRB; HIVEP1; TXNIP; ATOH1; IRX5; KMT2B; DMRT1; ST18; ZNF695; ZNF202; TBX1; SMARCA1; ZNF175; ARID5B; TRIM16; ZNF286A; ZNF74; SOHLH2; ZKSCAN5; E2F2; TLE4; RERE; PHIP; ZNF556; PRDM5; SOX17; RORC; ZIC1; NR3C2; HOXC11; HTATIP2; IRF9; BNC2; MSC; PAX1; ETV5; LIN28A; SLC2A4RG; HHEX; ADNP2; NFATC4; EYA1; NFRKB; ZNF254; TOX; TULP1; NR0B1; ESR2; SPEN; ZNF768; ZNF665; LHX2; TBX2; NR3C1; HIPK2; TBX10; PTRF; SMAD5; PATZ1; CDIP1; GFI1; IKZF3; TP73; FOXL2; ZNF688; ZNF580; LZTR1; TFCP2; TAF1C; ZNF14; ERCC3; NFYA; RFX1; MYCN; ZNF337; SPIB; TERF1; CDYL; CAMTA2; ZNF45; LHX3; ZNF350; TGIF2; AFF3; GRHL2; SP4; E2F5; ZNF354A; ZNF226; NANOG; ZNF24; STAT5B; HIC2; ZNF446; LHX1; TOX4; ZNF749; WWP1; ZNF287; ARID3B; DDX54; ZKSCAN8; BAZ1B; EPAS1; ZNF778; HIPK3; ARID4B; HIVEP3; TRAK1; ZNF611; BRWD1; WDR77; E2F6; EGR1; DDX17; ZNF415; TAF1; HCFC2; BNC1; GLI2; EHMT2; SHOX2; ELK4; USP21; ZNF141; SIRT7; RBBP4; PRDM10; NFE2L2; STAT4; ZNF157; FOSL1; SAFB; POU1F1; WWC1; PITX1; KDM4C; PPARG; CSDC2; HOXA4; MEF2C; PRDM2; ZNF675; NHLH1; PDLIM1; THAP1; CEBPD; POU2F1; MYBBP1A; ZNF331; PEG3; RFX7; HSF2; AES; HOXC8; TEAD1; SSBP3; ANKRD1; DEAF1; DNAJC1; ZNF764; AEBP1; TFAP2A; TSC22D4; BLM; ZNF211; ZNF652; CITED1; ZNF614; CXXC1; BACH2; ZEB2; WT1; CITED2; ZNF266; PAWR; OLIG2; TRPS1; DLX4; SIX6; SCMH1; E4F1; NR5A2; DNAJC2; ZSCAN18; ZNF292; CHD8; NLK; NR4A2; JUN; CBX6; TP63; SSX3; CNOT3; SOX21; TSC22D2; FOSL2; SP3; TGIF1; KAT2B; SMARCA5; TGFB1; FOXG1; KAT6B; ZFHX4; AR; ELF4; IL16; USP16; RBL2; HDAC4; GATA4; PCGF1; MYBL1; ZNF394; HIPK1; UBP1; MED24; SOX10; ZBTB1; BAZ1A; GATA6; KAT2A; MAFK; NFYC; CREB3L2; SMARCA2; SMARCC1; CIITA; MXD1; HLTF; PLAGL1; OSR2; PKNOX2; ZNF124; HOXB13; E2F8; EGR4; KMT2A; HDAC9; CUX2; SIX2; ZNF468; ISL1; SALL1; HLF; VGLL1; ZBTB16; FOXF1; HOXB7; PHF1; MITF; TCF21; CD3D; ZNF165; KAT6A; TCF4; SSX1; ZNF160; KLF4; TRIM29; HMGN3; TRIM22; BHLHE41; DLX2; SOX9
Down-regulation	345	TLE1; FOXJ3; PUF60; SCAND1; CLOCK; ATF4; CCNA2; NFIL3; DEK; MXI1; MAZ; NFKBIA; CARHSP1; TBP; FOXO3; DAXX; BRD8; RYBP; HOXD9; ESRRA; KAT5; BIRC2; HMGA2; DACH1; CTBP2; TCF25; MSL3; SP110; KLF7; HOXA7; NCOA4; VPS72; RFC1; NFKBIB; ECD; MXD3; ENO1; NFATC3; RBPJ; RELA; HDAC3; FHL2; BRCA1; USF2; ZNF148; ZNF143; ERF; HOXD10; ZNF23; CBFB; ATF3; BRD4; TULP3; MED27; FOXO4; PLAGL2; TFCP2L1; NR1I2; SIRT2; HMGB3; HDAC6; KLF6; HIRA; C1D; RELB; SP100; SOX4; SPI1; MED13; MYCL; VGLL4; CBX5; CCNC; MAFF; SUMO1; YBX1; MNT; CHD9; REST; ITGB3BP; RNF14; NRBF2; RFXANK; HDGF; ELK1; SP140L; ZBTB7A; PHF2; ZNF250; ZNF358; ZNF562; ZNF140; TP53; HOXD11; ORC2; PQBP1; NR1I3; YBX3; ZNF12; ZNF573; MDFI; BATF3; ZBTB11; ZZZ3; KAT8; IRF6; FLNA; SMARCE1; CREB3; NONO; MED12; TAF7; ZNF112; MTF2; SMARCA4; YWHAB; CCDC59; MAX; SND1; CNOT2; GATAD2A; TRIM27; ELF3; SMAD2; NFIC; PHF20; PSPC1; PCGF2; DPF2; ZNF232; ZNF408; PIR; RBM39; RNF10; DDIT3; CDK8; ETS1; NSD1; SIAH2; CENPF; ZFP30; ZNF16; ZNF710; JUND; ATF2; CEBPG; PBRM1; UBE2B; PROX1; NR1H3; RUVBL1; TAF10; LPIN2; PKNOX1; MAFG; PPRC1; CEBPE; TSG101; MLX; TRIM32; CEBPB; HDAC5; ABL1; ZNF426; MED16; KLF13; IRF7; CRY1; ZNF281; RXRB; MED25; BRD2; THAP4; ZNF189; SRF; NFKB1; MEF2A; VSX1; TEAD4; CCNT1; HOXD1; ZNF212; GTF2IRD1; NFIB; CARM1; MZF1; KLF1; MAFB; CNOT1; WWTR1; E2F1; ELF5; PRRX2; MAML1; BCL6; STAT6; HAND1; PRDM4; RCOR1; CIZ1; ZMIZ2; ID2; ZFP64; TRIM28; ELK3; BTAF1; MECP2; CERS6; SUPT4H1; ZNF33B; TAF5L; HOXD3; ZNF263; ZNF274; SSRP1; MED7; BTG1; MAGED1; HOXB9; NFX1; ZNF84; CDX1; ZNF532; ZNF184; SNW1; NRF1; ZNF587; STAT1; IFI16; LDB1; ZNF10; PPP1R13L; TAF1D; PMF1; ING3; PTTG1; BBX; NCOA6; INSR; TCERG1; ZNF131; TAL1; COPS2; ZBTB18; TBPL1; RLF; SATB2; DDX5; ATF1; KLF10; SMAD1; ING4; TBL1X; TAF9; PSMC3; NCOR2; KLF11; TBL1XR1; ARNT; SFPQ; TERF2; EHF; ZBTB20; ETV4; HOXA10; ZMIZ1; IKBKAP; TAF12; NPAS2; YEATS4; TGFB1I1; FOXM1; NPAT; LMCD1; ZNF552; ZBED4; TAF11; TOX3; PURA; CNOT6; KAT7; RING1; MLXIP; FOS; HNRNPD; UBE2I; EMX2; SMAD6; PBX3; RNF6; CERS4; NR2C1; RFX5; CRK; MYCBP; CREB1; TCF12; WHSC1; NR2F2; PRKDC; MEOX1; MEOX2; RNF111; MECOM; MED4; KLF5; PSIP1; TSC22D1; CREG1; MED21; HOXA11; PPARGC1A; ENY2; GTF3A; ZBED1; HIF1A; BAZ2B; SMAD7; RXRA; ELF1; CNBP; ERG; MAF; HDAC1; NFAT5; NR1H2; KDM5D; RHOA; HDAC2; TRIP6; MNAT1; ZNF146; HOXC6; USP22; ZFP36L1; ID3; CBX3; NRIP1; HBP1; HOXA5; NKX2-1; HOXB5; ID1; RBPMS; TCEB2