Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77278	Ingenol	GSE92742	NKDBA	Human	24h	1.1111uM	EID0449

Response Information :

Types	Number	Response transcription factors
Up-regulation	197	EGR1; IKZF1; FOXO4; OVOL2; SETDB1; PAX6; KLF9; GRHL2; SOX2; OSR2; IRF6; MSX1; RXRB; RFXANK; ZNF85; TGIF1; MYCL; HMGB2; TERF1; HDAC4; TCF7L2; PBXIP1; BRD2; DLX5; ZNF500; ETV6; PDX1; ZNF91; SOX13; CTNNB1; TFDP2; TBX21; HDAC9; NRL; ST18; DBP; FOSB; ZNF835; POU4F1; ZNF415; PRDM2; ZSCAN31; GCFC2; POLR3C; ZNF180; ZBTB7B; HMX1; TLE2; INSR; EGR2; LHX3; PEG3; NHLH1; ZNF816; LDB1; CEBPA; RREB1; SOX3; MLLT10; MKL1; NAB2; TAF5; MAZ; TCF15; HOXA3; SIX6; SMARCA2; VPS72; NCOA2; CSDE1; TFDP1; TULP1; SOX17; MLXIPL; HBP1; HIF3A; HOXB13; ZNF131; ARNT; JUN; NR1H2; NR1H3; RING1; ZNF562; DACH1; ARID1A; BARX1; ZNF551; HEY1; ZNF354A; HHEX; SPIB; ZNF544; NR0B2; ZNF74; BCL11A; HLX; ZNF423; ZNF224; ZNF573; BRD4; MYT1L; HSF4; MYOG; MXI1; RNF6; TFAP2A; ERBB4; SATB1; SLC2A4RG; NKX3-1; CDX2; MEIS2; FOS; CALR; MYBL2; EYA2; ZNF264; JUP; MECOM; TAF1; TFAP2C; ZIC1; PHIP; RNF10; SALL2; ZNF43; MYB; ARID5A; KLF13; NR1I2; TOB1; HOXB7; HOXD11; LIN28A; PNRC1; NFATC3; EGR4; EGR3; ZNF3; TRIM33; HOXB6; JUNB; NR4A1; BBX; ZNF646; ZIC3; NFIC; NFATC4; ZNF665; SMAD1; PRRX1; DDIT3; PHF20; SAP30; HOXC4; HMGA1; TP63; IRF9; NCOA3; INSM1; SMAD3; TCF7L1; TOX; TRIM24; TGFB1; KLF11; ZFPM2; REL; TRIM27; ZNF281; CCNT1; CITED1; TRPS1; CAMTA1; BAZ2A; TWIST1; MDM4; KLF5; FOXG1; NR4A2; SOX4; RBBP8; FOXF2; HIPK1; PSMC3; TCEA2; DAXX; MAF; ETS1; SSBP3; ATF5; PBX1; SCAND1; SNAI2; CITED2; ID1
Down-regulation	169	CDK7; NR2F2; SMARCE1; ZFP36L1; HSBP1; NCOR1; ZBTB1; FHL2; HMGB3; TSC22D3; MED6; BACH1; ERBB2; E2F5; MYBL1; MED7; VEZF1; BPTF; BCL6; KAT6A; PATZ1; HNRNPD; FHL5; YAF2; PCGF3; RBM14; FOXJ3; HMGN3; USP22; ZNF14; CHD1; SF1; RARA; GATAD2A; TFEC; BASP1; TFAM; MAGED1; DNAJC1; CEBPG; SP110; SUPT4H1; BCL3; ETS2; FOXC1; SNW1; BLZF1; KAT6B; ZNF770; UBE2B; NRBF2; NCOA4; DDX5; SMARCD2; XBP1; MEN1; MED4; KLF12; TRIM32; SETD2; BAZ1A; CCNH; HOXB9; ZMYM2; RAN; BCLAF1; SFPQ; NPM1; SMAD7; TEAD4; RUVBL2; BRD8; C1QBP; CREB3L2; CTBP1; MAFG; ZKSCAN7; ZNF432; KLF4; JUND; TEAD1; GTF3A; ZFHX3; BAZ1B; FLNA; BACH2; SMARCB1; ZBTB38; SMARCA5; NCOR2; TBP; NLK; CTCF; HIVEP1; CDK8; KLF2; HOXB2; SUB1; SIX2; TGFB1I1; PBRM1; BATF3; PHF2; PCGF2; PAX5; PIAS3; WHSC1; NELFB; CREB1; WWC1; ZBED2; TRRAP; BHLHE40; ID2; TSC22D2; RHOA; CARHSP1; TCF3; PITX2; SREBF1; GTF2I; PUF60; RBPMS; ELK3; HOXC6; KAT2B; CREG1; SIRT7; CBFB; NFYB; SPEN; VGLL4; ZBTB18; E2F6; ELF1; MED24; ZNF226; CEBPB; EYA1; HMGB1; FOXF1; HOXC10; FOSL1; AIP; ENO1; TRIM16; RCOR1; SOX11; LEF1; UBP1; HTATIP2; ARID4B; DNMT1; RFX5; HMG20B; ECD; BAZ2B; RBPJ; MAFB; VDR; POU2AF1; NFKB2; ELF3; ATF3; SSBP2; NR2F1; HMGA2; ZNF274; TP53