Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77276	Ingenol	GSE92742	NKDBA	Human	24h	10uM	EID0449

Response Information :

Types	Number	Response transcription factors
Up-regulation	347	GATA3; HR; KLF3; ETV1; PPARD; ZBED1; STAT5B; XBP1; HEY1; IRX5; TDRD3; LIMD1; HLF; NR1H2; EHMT1; HOXC11; CUX1; GLI1; ASXL1; CENPB; PPARG; ZSCAN32; ABT1; ESRRA; CNOT2; NR3C1; HOXD3; FOXC1; NPM1; MEF2A; NFYA; SPDEF; TRIM29; USP16; HABP4; MBD1; TFAP2C; RNF141; ERCC3; CREM; GABPB1; ZMYM2; ZSCAN31; HES1; HOXC13; SP140; NKX3-2; PRDM1; FOXJ2; AFF4; TOX4; CHD1; ERBB4; FOSL2; RORA; SMARCD1; TRPS1; HMGB2; MAFK; IRF5; GLI3; ZNF536; HMBOX1; ZNF467; ZKSCAN3; ZNF384; DLX4; PBXIP1; ESR1; GRHL2; PML; NCOA2; ZNF556; FOXM1; DEAF1; SNAPC4; PRDM2; CREB1; IRF6; IKZF5; HMX1; ARID3B; ZNF219; POU2F1; DDX54; RREB1; GTF2I; PEG3; RBBP8; BLM; DAXX; ZNF335; CNOT3; EVX1; FOXN1; AIRE; PEX14; KAT7; MAML1; IL16; ZNF211; NFKB1; ZNF446; TGIF2; BARX2; EBF2; DLX2; TRAK1; MYOG; ETV4; PSPC1; EPAS1; ASH1L; HOXC10; MNX1; SSX3; ZNF286A; CBL; ZBTB25; POU3F1; CBX8; ZNF331; RFX2; RARG; NFKB2; PRDM4; SOX10; ZNF778; MYBL2; FOXI1; ATF6; BTF3; BATF; PAX6; TFDP2; STAT2; PHIP; NEUROD6; HOXA4; CHD2; ZNF614; NFX1; NAB2; HIC2; POLR2A; HOXC4; SFMBT1; MXD3; ELK4; ZNF510; SMAD1; TRIM25; CDK9; CBX2; MEN1; SMARCA1; FHL5; NRL; ARNTL; TAF6L; ESRRG; PAX5; TEAD3; EYA3; E2F1; DBP; SMARCD2; ZNF16; ZBTB32; CHAF1B; ZNF835; HIPK3; DNAJC1; ZSCAN5A; CIC; RBBP4; EMX1; ZNF324B; SRF; MECOM; OSR2; RXRA; MXD4; ZXDC; HOXD1; LHX2; HOXC6; FOS; PRDM10; HOXA11; HOXD11; ZBTB7B; KAT6B; PRRX2; NR3C2; KAT6A; NHLH1; SSBP3; SFPQ; NR4A3; EYA2; RNF14; JUP; RELB; CEBPA; POU4F1; CLOCK; ARID1A; HOXA7; SP110; HMGXB3; SLC2A4RG; MED15; IRF4; RUNX3; ZNF512B; RNF10; RBM14; E2F2; ZNF266; HSF4; PITX1; TAF9B; UIMC1; ZNF263; THAP3; OVOL1; AIP; ZZZ3; CAPN15; MTF2; ZNF7; ZIM2; NONO; PCGF3; FEV; GTF2F1; ZMIZ2; SOX21; ZIC1; ZNF75D; TAF4B; SOX4; NEUROG1; ARID5A; CAMTA1; BCL11B; STAT3; SOX18; NOC2L; MEF2D; SIX1; ZNF107; FOXE1; TP73; ZNF33B; TP63; RNF4; FOXA1; JUNB; BRWD1; ZNF444; PIAS2; ELF1; SOHLH2; ZNF44; BHLHE41; TRIM27; HDAC1; ZNF710; NKRF; EGR3; LHX3; MXD1; TEAD1; TFE3; YAP1; FOXJ1; FUBP1; MEOX2; NR0B1; DMTF1; CREB3L2; ZFHX4; MYOD1; KLF4; NR2F2; PBX1; RCOR1; RFX5; PAWR; RBPJ; HDAC4; BCL11A; PHOX2B; FOXG1; CBX7; CREBZF; MED6; SIRT2; ZNF189; RUVBL1; ZNF200; TBX3; BRPF1; NR4A2; ZNF264; IRF7; ZNF652; ZNF117; DDX5; DLX5; CITED1; HOXA5; ZNF304; PUF60; FOXA2; MTA1; PARP1; KLF2; ZNF3; TCEA2; TBL1X; CALR; CNOT6; TCF7; HIVEP1; CREB3L1; SSX1; CD3D; LITAF; LIN28A; ZNF217; KDM5A; SOX17; PAXBP1; ECD; FLNA; TRIM28; PIR; FOXD1; POU2AF1; REL; ELF3; SSBP2; VDR; KDM5D
Down-regulation	327	PDLIM1; TRIB3; CCNA2; BIRC2; ZMIZ1; ATF1; THAP11; PSIP1; MYCBP; PTRF; FHL2; GATAD2A; ACTL6A; VEZF1; CEBPG; THAP1; SUV39H1; YEATS2; TFAM; SPI1; HIRA; ZNF146; ZNF22; BAZ1B; ZBTB38; SUPT7L; TBPL1; NLK; HDAC5; TCF21; CTBP2; SUZ12; TCEA1; PHF8; ZBTB7A; MYC; RRN3; BCL10; ZNF302; MAZ; TOX3; ARL2BP; FOXJ3; HSBP1; MAFF; ZNF768; PRKDC; ZBED4; MITF; TAL1; ZNF148; INSM1; GATA6; ZEB2; VSX1; CDYL; ADNP; UBE2I; ARNT; ZNF770; ENY2; ZBTB1; SMARCE1; FOXO1; FOXO3; CHD8; TLE2; HIF1A; CRY1; GFI1B; HOXB9; ZNF222; NFKBIB; TBP; MED31; BLZF1; CEBPB; COPS5; ATF4; USP22; RORC; CCNC; NUP62; MED23; SUPT4H1; TSC22D1; STAT6; HTATIP2; NFYB; ZNF133; ZNF23; CBFB; BRD4; MTF1; TAF1A; HMG20A; TCF12; L3MBTL1; HDAC9; ZFPM2; TOB1; SATB2; HMG20B; MED24; NR1I2; CHD9; BCL6; ATF5; HOXB6; AR; ZNF334; CEBPZ; PQBP1; MLXIPL; FOXO4; POLR3F; MXI1; RBBP5; HOXB1; ZNF143; TERF2; KLF9; SRCAP; FOSB; TRAF6; MDFI; ZFP30; ZSCAN12; MMS19; MED1; SNAI2; PRMT2; CHD7; SMAD3; KAT2A; ING4; RFXANK; ZNF468; RBFOX2; PMS1; VGLL1; ZNF576; SUB1; PRDM12; BRF2; POU4F3; CHD4; TAF6; PHF2; SAP18; HOXB7; SIX2; ZBTB18; ZNF345; ZNF83; LOXL2; TAF4; PTTG1; ESR2; THAP4; YEATS4; GATA1; TGIF1; BCOR; RBM39; IFI16; WNT4; FOXN2; TBL1XR1; ZNF500; CIZ1; TFCP2; CDK2; NR1H4; HMGB3; PATZ1; FOXN3; SND1; CDK8; ZKSCAN1; ATF3; MED13; HOXB5; TCEB2; ZNF215; ZNF573; ZNF329; ZNF177; MNT; ZNF529; C1D; ZNF432; ZNF551; MYBL1; PBX3; TGFB1I1; IRF8; RLF; CUX2; ATF2; BBX; NPAT; ZBTB24; RB1; ZNF623; PEX2; NRIP1; PSMC3IP; BAZ1A; NFIB; TULP3; NR5A2; FOSL1; ZNF423; ZBED2; PBRM1; UBP1; KLF1; SMARCB1; ALX1; ZEB1; ETS2; ZNF281; HBP1; DEK; ZNF10; ABL1; CERS6; ERCC2; TCF20; THRA; NCOR1; TAF5L; NR1H3; PLAGL1; MSX1; ZNF337; POLR3C; MYRF; NELFB; MED17; ZNF611; ZNF140; IRF9; TADA3; MYT1; JARID2; MYNN; HOXB2; NCOA3; TCERG1; CTNNB1; MED16; YBX1; WWP1; MAFB; SOX11; SPEN; REPIN1; TRIP6; ZKSCAN7; ZNF268; MED14; ZBTB20; SKIL; KLF11; ZFP36L2; NFE2L3; VPS72; SP2; HSF2; WWTR1; EHF; HMGA2; ZFP69B; HDGF; ARNTL2; CREG1; THAP10; ID4; TFEC; AEBP1; ZNF410; YBX3; YWHAB; TCF7L2; BCLAF1; TAF7; GTF2IRD1; SMARCA4; SMARCA2; ZNF274; ZNF667; IRF2; ING2; TTF1; TTF2; TAF10; ZNF12; EYA1; ZNF32; NR4A1; ERG; TLE1; ETV5; BASP1; ID2; ARID4B; TOX; SMAD4; TOPORS; KLF10; BTG1; LEF1; ZNF544; BAZ2B; TP53; ZNF131; ELK3; NR1D2; EMX2; NFAT5; DNMT1; WT1; NR2F1; SOX9; SCAND1