Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID77262	Cgs-15943	GSE92742	NKDBA	Human	24h	20uM	EID0449

Response Information :

Types	Number	Response transcription factors
Up-regulation	318	GATA3; PPARG; MKL2; ERBB4; IKZF1; SOX2; GATA2; HIC2; GLI2; CEBPA; CCNE1; CREM; ETV1; SPDEF; TCFL5; MEF2C; BNC2; TGIF2; ZBED1; SOX5; CNOT3; ASXL1; PLAGL2; NR1H2; NRL; GLI3; ARID3A; BCL11A; RYBP; HOXB2; RARG; KLF3; STAT3; TSG101; PRDM1; NHLH1; KAT6A; TCF7L2; FOXJ1; ATN1; THRB; HLX; STAT2; TFAP2C; WDR77; PAX6; SOX13; ETS2; UBE2B; TRIM25; BARX1; ZBTB7B; JUNB; APBB1; MECOM; PEG3; MYBL1; CREB1; HIVEP1; SATB2; XBP1; TRPS1; TBX1; E2F8; E2F5; FLI1; HOXB1; RXRA; HEYL; ELF4; CDYL; TLE4; ZNF215; E2F1; SOX17; JUN; ESR1; NFE2; ZBTB44; PRDM2; KLF15; UBE2L3; ZKSCAN4; CTBP2; ZNF552; ZNF589; EPAS1; NFX1; TAF5; FUBP1; ESRRG; ZNF771; ZNF536; PAX1; NFATC4; ALX4; ABT1; ARID3B; HDAC11; CREB3L2; DLX2; BARX2; NR4A2; GBX1; HOXC4; TULP3; YAP1; MXD4; PRDM14; ZNF816; BRD7; MYCN; KDM5C; LHX3; ESRRA; BPTF; HIPK2; LHX2; LZTR1; HOXC13; GATA1; MYB; BRCA1; ASCL3; MAK; PROP1; NCOA3; HOXD1; NEUROD2; NR0B2; PLAG1; NFKB2; PML; USP16; ZNF556; HOXC8; LIN28A; NR3C1; EMX1; ZNF253; TTF2; RING1; CHAF1B; PCGF1; GFI1B; BATF; RFX2; ZNF423; SP140; THAP7; IRF6; CBFA2T2; SOX21; AIRE; TAF6L; HOXD3; HHEX; ST18; HOXB6; ZNF764; CALR; TCF4; ELK3; TOB1; EVX1; KAT6B; IRF1; FOXH1; NCOA2; RELA; CBX4; RB1; HOXC11; SOHLH2; MBD1; MED14; MYBL2; RORA; SPI1; NFKBIB; MED25; LYL1; ZNF711; NAB1; SAP130; MXD3; OVOL1; TWIST1; NFYA; SIRT2; POU2F2; SRCAP; TAF4B; HNF1A; OVOL2; IRF4; BRWD1; PRMT2; BNC1; CREB3; ING4; KLF4; CDX1; ATOH1; NPAT; PHIP; E4F1; CEBPD; ZNF668; RUNX3; REL; NKX2-1; SSX1; TRIM29; HOXB5; SNAI1; TSC22D2; GRHL2; SOX18; HSF1; SIN3B; ARID5A; ZNF217; WT1; ZNF248; TP73; HIPK3; SOX4; ZNF131; PAXBP1; KLF7; SSBP3; TUB; ZNF444; DEAF1; YEATS4; TULP4; ZNF665; TAL1; PRRX2; SP2; TAF1A; SOX12; FOXO1; NAB2; RUNX1; ZNF528; FOXG1; NFE2L3; ZNF688; PPP1R13L; CDK9; CTR9; ELK4; ZNF586; PIR; HLF; CBFA2T3; NR4A3; SMARCB1; BACH2; FOXI1; BCOR; ZNF24; FOXO4; VPS72; NEUROD1; ZNF672; NCOA1; SMARCA1; TGFB1; MEIS1; MAP3K10; PRRX1; NFATC3; CDK2; MEIS2; IRF7; NFE2L2; ZNF331; VDR; ZBTB18; HDAC9; TOX; JUP; ETS1; KLF13; TCF7; INSM1; EGR3; IL16; SMAD7; PROX1; EMX2; SMAD1; RFX5; ATF3; PIAS3; E2F3; CITED2; PAWR; ZFP36L2; RUVBL1; TRIM27; PRPF6; PSMC3; SMARCD3; ZNF652; PURA; TCEA2; PLAGL1; KLF2; IRF8; KDM5D; ZIC1; RBPMS; FOXD1; HOXB7
Down-regulation	293	PDLIM1; PTTG1; ABL1; CBX5; ERBB2; PSIP1; ENY2; USP22; UBE3A; SMARCD2; SUV39H1; NR2F2; PTRF; MYCBP; CCNA2; YEATS2; RLF; YBX3; TCEB2; UBE2I; CTBP1; TGFB1I1; HMGB2; ADNP2; REPIN1; FOXJ3; SALL1; HDAC6; BRD2; SRF; YBX1; ATF1; SAP18; HES1; BAZ1B; HOXA5; MTA1; COPS2; ZNF146; MED24; NUP62; PHF8; MED23; HOXA10; TFAM; MITF; ZNF562; CBX3; SMARCE1; FLNA; NELFB; DR1; MNT; NFIL3; WWTR1; CREB5; FOXO3; ITGB3BP; MYC; HIF1A; NR1H3; TBPL1; ZNF148; TLE2; ZBTB24; MED27; BRD4; SMARCC1; HNRNPD; ATF4; ZSCAN18; CBFB; DMRT1; HOXD11; ZNF593; EWSR1; HMGB1; PRKDC; NR1I2; TBL1X; TDRD3; ATF7IP; HMGN3; HSBP1; CCDC59; SIX2; SAP30; USF2; SNW1; C1QBP; SP140L; ZNF334; SMARCA2; KLF6; PCBD1; TAF9; SUPT4H1; RNF10; TAF12; DNAJC1; CRK; ELF5; CARM1; EDF1; ZNF160; WHSC1; APEX1; TBL1XR1; ZNF8; ARL2BP; EGR2; TADA3; ZNF813; NSD1; NR2C1; ZBTB7A; MAGED1; YWHAB; MTDH; FOSL1; ZSCAN12; CNBP; NFKBIA; ARNT; CIZ1; CEBPZ; ZNF23; ZNF571; GTF2IRD1; RFXANK; ZBTB20; PHF2; CHD4; ZMIZ2; CEBPB; SMARCA4; EHMT2; NCOA6; CNOT2; HDAC2; NFYB; CITED1; SPEN; CNOT1; ZNF606; TRIM16; ZNF532; PAX8; HCFC2; INSR; HMGXB4; RUVBL2; ZNF329; HMG20A; SOX11; TFCP2; MED1; ZNF302; TRRAP; TCEA1; ZBTB14; MLXIPL; ZNF573; NFE2L1; HOXA4; TAF11; SMAD3; KLF5; ZNF45; CDC5L; ZNF155; STAT5B; ZNF22; SOX15; HEY2; MGA; MLX; SUB1; C1D; ZNF189; PIAS2; CCNC; DDIT3; SSRP1; JARID2; SCMH1; AATF; ELF3; ZNF770; CENPF; TBP; HDAC1; RNF6; KLF9; TTF1; ZMYM2; ZNF468; ZNF675; ZNF32; GTF3A; RERE; NFIB; ETV6; DNAJC2; ZBTB11; MYBBP1A; ARNTL2; BCL6; AFF1; EGR4; SMARCC2; ZNF529; BRD3; ZNF10; SUMO1; ING2; FOXF1; STAT6; TFEC; PCGF3; BMI1; PBX3; BCLAF1; NKX3-1; ZEB2; LMCD1; TCF12; MBD2; ZNF165; BHLHE41; POLR2A; ZNF12; ELF1; TBX2; DMTF1; TCF3; WWC1; ZZZ3; ID3; TAF10; AHR; NEDD8; ZNF84; SIAH2; PCGF2; HSF2; TOX3; KLF11; SFPQ; DPF2; RBPJ; NRBF2; BRD8; CREG1; MED21; TCF21; CHD7; CREB3L1; MMS19; BAZ1A; EHF; KMT2B; WWP1; ISL1; TP53; ZFP69B; MSX1; AR; TSC22D1; DNMT3B; HMGA2; TERF2; MAF; ID1; PMS1; RNF4; NONO; DEK; TRIP6; ZNF264; ZNF410; RHOA; ZKSCAN1; MAX; STAT4; MXI1; MAFB; SSBP2; NR2F1; ID2; DNMT1; SNAI2; SCAND1